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TPMPA
go.drugbank.com/drugs/DB16754Experimental[A245303] GABA<sub>C</sub> receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut … [A245308,A245313] TPMPA is used as a pharmacological probe for the investigation of GABA<sub>C</sub> receptor function.[A245313]
Probiorinse
go.drugbank.com/drugs/DB15870Experimental[L16368] This strain of bacteria is said to have salubrious effects on the microbiome of the nasal cavity and sinuses.[A220193] … Probiorinse is an intranasal probiotic treatment composed of a pre-mixed and buffered sinus irrigation solution that contains the probiotic bacteria Lactococcus lactis W136.
Aphidicolin
go.drugbank.com/drugs/DB17742ExperimentalAphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Dithiopyr
go.drugbank.com/drugs/DB15230InvestigationalDithiopyr is under investigation in clinical trial NCT01236781 (Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates).
Verzistobart
go.drugbank.com/drugs/DB18895InvestigationalVerzistobart is under investigation in clinical trial NCT06056895 (Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma).
CFG-920
go.drugbank.com/drugs/DB19193InvestigationalCFG-920 is under investigation in clinical trial NCT04060394 (Dose-escalation and Efficacy Study of Lae001/prednisone Plus Afuresertib Patients With M-crpc).
PF-06821497
go.drugbank.com/drugs/DB14799InvestigationalPF-06821497 is under investigation in clinical trial NCT03460977 (PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma).
AZD-8418
go.drugbank.com/drugs/DB13102InvestigationalAzd8418 is under investigation in clinical trial NCT01027234 (This Study Will Assess the Safety and Tolerability of AZD8418 After Single Increasing Oral Doses).
Dextromoramide
go.drugbank.com/drugs/DB01529ExperimentalIllicitAn opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
Hopantenic acid
go.drugbank.com/drugs/DB14044ExperimentalHopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome. [A33115] … Hopantenic acid (Pantogam) is a central nervous system depressant.
Synonyms: N-pantoyl-GABA