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  1. Target

    Fibrinogen

    go.drugbank.com/bio_entities/BE0009672
    TargetHumans

    Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. … Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.

    Polypeptides: Fibrinogen alpha chain, Fibrinogen beta chain
  2. Target

    Fibrinogen alpha chain

    go.drugbank.com/bio_entities/BE0000538
    TargetHumans

    Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. … May also facilitate the immune response via both innate and T-cell mediated pathways

    Polypeptides: Fibrinogen alpha chain
  3. Target

    Fibrinogen beta chain

    go.drugbank.com/bio_entities/BE0002091
    TargetHumans

    Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. … May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways

    Polypeptides: Fibrinogen beta chain
  4. Target

    Prothrombin

    go.drugbank.com/bio_entities/BE0000048
    TargetEnzymeHumans

    Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. … Functions in blood homeostasis, inflammation and wound healing.