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  1. Target

    Lethal factor

    go.drugbank.com/bio_entities/BE0001363
    TargetBacillus anthracis

    LF is not toxic by itself and only acts as a lethal factor when associated with protective antigen (PA) to form the lethal toxin (LeTx): PA is required for LF translocation into the host cytosol (PubMed … Lethal factor (LF), which constitutes one of the three proteins composing the anthrax toxin, is able to trigger rapid cell death in macrophages (PubMed:10475971, PubMed:11104681, PubMed:3711080, PubMed

    Polypeptides: Lethal factorSynonyms: Anthrax lethal toxin endopeptidase component
  2. Target

    Lethal(3)malignant brain tumor-like protein 1

    go.drugbank.com/bio_entities/BE0003191
    TargetHumans

    Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcript...

    Polypeptides: Lethal(3)malignant brain tumor-like protein 1
  3. Target

    KAT8 regulatory NSL complex subunit 3

    go.drugbank.com/bio_entities/BE0009091
    TargetHumans

    Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiat...

    Synonyms: Non-specific lethal 3 homolog