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  1. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase … Tenofovir disoproxil was initially approved in 2001 [FDA label].

    Synonyms: Tenofovir bis(isopropyloxycarbonyloxymethyl) esterSalts: Tenofovir disoproxil fumarate, Tenofovir disoproxil maleate
  2. Drug

    Tenofovir alafenamide

    go.drugbank.com/drugs/DB09299
    ApprovedInvestigational

    Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil]. … [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil.

    Synonyms: Tenofovir alafenamideSalts: Tenofovir alafenamide fumarate
  3. Drug

    Emtricitabine

    go.drugbank.com/drugs/DB00879
    ApprovedInvestigational

    Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection

    Mixtures: Emtricitabine and Tenofovir Disoproxil Fumarate, Emtricitabine and Tenofovir Disoproxil FumarateCategories: tenofovir disoproxil and emtricitabine, emtricitabine, tenofovir disoproxil and efavirenz
  4. Drug

    Efavirenz

    go.drugbank.com/drugs/DB00625
    ApprovedInvestigational

    For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen.

    Mixtures: Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate, Efavirenz, Lamivudine and Tenofovir Disoproxil FumarateCategories: lamivudine, tenofovir disoproxil and efavirenz, emtricitabine, tenofovir disoproxil and efavirenz
  5. Drug

    Doravirine

    go.drugbank.com/drugs/DB12301
    ApprovedInvestigational

    [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg).

    Categories: lamivudine, tenofovir disoproxil and doravirine
  6. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

    Mixtures: Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate, Efavirenz, Lamivudine and Tenofovir Disoproxil FumarateCategories: lamivudine and tenofovir disoproxil, lamivudine, tenofovir disoproxil and efavirenz
  7. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent to...

    Mixtures: TELDY (Dolutegravir 50mg/Lamivudine 300mg/Tenofovir Disoproxil Fumarate 300mg) Film-Coated Tablets, ACRIPTEGA DOLUTEGRAVIR/ LAMIVUDINE/TENOFOVIR DISOPROXIL FUMARATE FILM COATED TABLETS (50 MG/300 MG/300 MG)Categories: lamivudine, tenofovir disoproxil and dolutegravir, emtricitabine, tenofovir alafenamide and dolutegravir
  8. Drug

    Rilpivirine

    go.drugbank.com/drugs/DB08864
    ApprovedInvestigational

    Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpiv...

    Mixtures: Emtricitabine, Rilpivirine, Tenofovir Disoproxil Fumarate, Emtricitabine, Rilpivirine and Tenofovir Disoproxil FumarateCategories: emtricitabine, tenofovir disoproxil and rilpivirine, emtricitabine, tenofovir alafenamide and rilpivirine
  9. Drug

    Fosclevudine alafenamide

    go.drugbank.com/drugs/DB19113
    Investigational

    Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With