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Flavohemoprotein
go.drugbank.com/bio_entities/BE0001704TargetCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various
Synonyms: NO oxygenaseFlavohemoprotein
go.drugbank.com/bio_entities/BE0002917TargetEscherichia coli (strain K12)Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various
Synonyms: NO oxygenaseNitric oxide synthase, inducible
go.drugbank.com/bio_entities/BE0000005TargetEnzymeHumansProduces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7504305, PubMed:7531687, PubMed:7544004, PubMed:7682706). … In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).
Synonyms: Inducible NO synthaseNitric oxide synthase
go.drugbank.com/bio_entities/BE0010197TargetEnzymeProduces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. … Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway (PubMed:1378832).
Synonyms: Inducible NO synthaseInactive phospholipase C-like protein 1
go.drugbank.com/bio_entities/BE0001081TargetHumansShows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity).
Synonyms: Phospholipase C-related but catalytically inactive proteinImmunoglobulin heavy constant alpha 2
go.drugbank.com/bio_entities/BE0004610TargetHumansConstant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglo...
Synonyms: Ig alpha-2 chain C region BUTImmunoglobulin heavy constant alpha 1
go.drugbank.com/bio_entities/BE0005097TargetHumansConstant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglo...
Synonyms: Ig alpha-1 chain C region BURImmunoglobulin heavy variable 3-30
go.drugbank.com/bio_entities/BE0004312TargetHumansV region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Synonyms: Ig heavy chain V-III region BUR