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Obexelimab
go.drugbank.com/drugs/DB15032InvestigationalObexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Synonyms: XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO 400-FOLD OVER NATIVE IGG) TO FCGRIIB)Gliquidone
go.drugbank.com/drugs/DB01251ApprovedGliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, an...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: GLURENOR TABLETTEN, GLURENOR 30 MG TABLETTENRice bran oil
go.drugbank.com/drugs/DB11293ApprovedInvestigationalRice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It contains monosaturated fatty acids, polyunsaturated fatty acids,...
Products: Claritying turn over rice perfect oil foam cleanserAvobenzone
go.drugbank.com/drugs/DB09495ApprovedInvestigationalAvobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens.
Mixtures: Bobbi Brown All Over Bronzing Gel SPF 15, Exuviance Optilight All-Over Dark Spot Minimizer SPF 25Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesDoxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigationalDoxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasti...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: CARDULAR PP 4MG, CARDULAR PP 8MGSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalSpironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed pur...
Mixtures: Tabletten, Spirono Genericon comp. forte TablettenCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 InhibitorsLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalA subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also available.
Mixtures: Xyliette 0,1 mg/0,02 mg - überzogene Tabletten, Rigevidon 30 Mikrogramm/150 Mikrogramm überzogene TablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigationalBupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an ai...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: Bupropion Accord 300 mg Tabletten mit veränderter Wirkstofffreisetzung, Bupropion Accord 150 mg Tabletten mit veränderter WirkstofffreisetzungUrtica dioica pollen
go.drugbank.com/drugs/DB10763ApprovedUrtica dioica pollen is the pollen of the Urtica dioica plant. Urtica dioica pollen is mainly used in allergenic testing.
Synonyms: nettle pollen extractProducts: Nettle, Nettle PollenAntithrombin III human
go.drugbank.com/drugs/DB11598ApprovedInvestigationalA plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Products: Kybernin P 500 I.E./1000 I.E. Pulver und Lösungsmittel zur Herstellung einer Injektions- oder Infusionslösung, KYBERNIN P