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  1. Pathway

    Tamoxifen Action Pathway

    smpdb.ca/view/SMP0000471
    Drug action

    Tamoxifen is a selective estrogen modulator (SERM) used in the treatment of estrogen-sensitive breast cancer. … Tamoxifen itself only has weak anti-estrogen effects and must be converted into more active metabolites to have therapeutic activity.

    Drugs: Tamoxifen · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · Formaldehyde
  2. Pathway

    Tamoxifen Metabolism Pathway

    smpdb.ca/view/SMP0000606
    Drug metabolism

    Tamoxifen is a selective estrogen modulator (SERM) used in the treatment of estrogen-sensitive breast cancer. … Tamoxifen itself only has weak anti-estrogen effects and must be converted into more active metabolites to have therapeutic activity.

    Drugs: Tamoxifen · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · Formaldehyde
  3. Pathway

    Tamoxifen Anti-Cancer Action Pathway

    smpdb.ca/view/SMP0124698
    Drug action

    Overdose of tamoxifen leads to acute neurotoxicity seen by tremors, hyperreflexia, unsteady gait, and dizziness. Tamoxifen is usually administered in an oral form in a tablet or solution form. … Tamoxifen is an anticancer drug that is a selective estrogen receptor modulator also known as a non-steroidal anti-estrogen.

    Drugs: Tamoxifen · Estradiol · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · Formaldehyde