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  1. Target

    Disintegrin and metalloproteinase domain-containing protein 17

    go.drugbank.com/bio_entities/BE0003754
    TargetHumans

    Transmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins including adhesion proteins, growth factor precursors and cytokines important for inflammation and immunity (PubMed:24226769, PubM...

    Synonyms: Snake venom-like protease
  2. Target

    Esterase EstA

    go.drugbank.com/bio_entities/BE0003982
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes is unclear. In vitro, has pronounc...

    Synonyms: papA
  3. Target

    Poly [ADP-ribose] polymerase tankyrase-1

    go.drugbank.com/bio_entities/BE0012352
    TargetHumans

    Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking (PubMed:10988299, PubMed:11739745, PubMed:16076287, PubMed:19759537, PubMed:21478859, PubMed:22864114, PubMe...

    Synonyms: PARPL