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Displaying results 1 - 10 of 70 in total
  1. Target

    Voltage-dependent calcium channel

    go.drugbank.com/bio_entities/BE0004902
    TargetHumans

    Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. … Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H

    Polypeptides: Voltage-dependent calcium channel gamma-1 subunit, Voltage-dependent calcium channel gamma-2 subunitSynonyms: Neuronal voltage-gated calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-3 subunit
  2. Target

    Voltage-gated Potassium Channels

    go.drugbank.com/bio_entities/BE0009847
    Target

    Homotetramer channels mediate delayed-rectifier voltage-dependent potassium currents that activate rapidly at high-threshold voltages and inactivate slowly. … Mediates the voltage-dependent potassium ion permeability of excitable membranes.

    Polypeptides: A-type voltage-gated potassium channel KCND1, A-type voltage-gated potassium channel KCND2Synonyms: Voltage-gated K(+) channel HuKI, Voltage-gated K(+) channel HuKIV
  3. Target

    Voltage-gated potassium channel KCNC2

    go.drugbank.com/bio_entities/BE0004724
    TargetHumans

    Homotetramer channels mediate delayed-rectifier voltage-dependent potassium currents that activate rapidly at high-threshold voltages and inactivate slowly. … Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain.

    Polypeptides: Voltage-gated potassium channel KCNC2Synonyms: Voltage-gated potassium channel Kv3.2, Potassium voltage-gated channel subfamily C member 2
  4. Target

    Voltage-gated potassium channel KCNC3

    go.drugbank.com/bio_entities/BE0004725
    TargetHumans

    Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. … The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient.

    Polypeptides: Voltage-gated potassium channel KCNC3Synonyms: Voltage-gated potassium channel subunit Kv3.3, Potassium voltage-gated channel subfamily C member 3
  5. Target

    Voltage-gated potassium channel KCNC4

    go.drugbank.com/bio_entities/BE0003319
    TargetHumans

    Voltage-gated potassium channel that opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical

    Polypeptides: Voltage-gated potassium channel KCNC4Synonyms: Voltage-gated potassium channel subunit Kv3.4, Potassium voltage-gated channel subfamily C member 4
  6. Target

    Voltage-gated potassium channel KCNC1

    go.drugbank.com/bio_entities/BE0004723
    TargetHumans

    Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298

    Polypeptides: Voltage-gated potassium channel KCNC1Synonyms: Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4
  7. Target

    Voltage gated L-type calcium channel

    go.drugbank.com/bio_entities/BE0009739
    TargetHumans

    Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group … The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation

    Polypeptides: Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1DSynonyms: Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-gated calcium channel subunit alpha Cav1.3
  8. Target

    Voltage-gated sodium channel alpha subunit

    go.drugbank.com/bio_entities/BE0009738
    TargetHumans

    Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operate by switching between closed and open conformations depending on the voltage difference across … Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operate by switching between closed and open conformations depending on the voltage difference across

    Synonyms: Voltage-gated sodium channel subunit alpha Nav1.1, Voltage-gated sodium channel subtype IIIFunction: voltage-gated sodium channel activity, voltage-gated sodium channel activity
  9. Target

    Voltage-dependent L-type calcium channel

    go.drugbank.com/bio_entities/BE0008715
    TargetTransporterHumans

    Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group … The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation

    Polypeptides: Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1DSynonyms: Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-gated calcium channel subunit alpha Cav1.3
  10. Target

    Voltage-dependent T-type calcium channel

    go.drugbank.com/bio_entities/BE0008716
    TargetTransporterHumans

    Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. … Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H

    Polypeptides: Voltage-dependent T-type calcium channel subunit alpha-1G, Voltage-dependent T-type calcium channel subunit alpha-1HSynonyms: Voltage-gated calcium channel subunit alpha Cav3.1, Voltage-gated calcium channel subunit alpha Cav3.2