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Perampanel

go.drugbank.com/drugs/DB08883
ApprovedInvestigational

Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warni...

  1. Pathway

    Perampanel Drug Metabolism

    smpdb.ca/view/SMP0130782
    Metabolic

    Perampanel passes through the liver and is then excreted from the body mainly through the kidney. … Perampanel is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Perampanel
  2. Indication

    Epilepsy, Primary Generalized Tonic-Clonic Seizures

    go.drugbank.com/conditions/DBCOND0054806
    Drugs: Perampanel · Topiramate
  3. Indication

    Partial onset Seizures

    go.drugbank.com/conditions/DBCOND0032900
    Drugs: Brivaracetam · Cenobamate · Clorazepic acid · Eslicarbazepine acetate · Gabapentin · Gamma-amino-beta-hydroxybutyric acid +13 more