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Displaying results 1 - 10 of 5739 in total
  1. Drug

    Warfarin

    go.drugbank.com/drugs/DB00682
    ApprovedInvestigational

    Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. … Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America.

    Synonyms: Warfarin, WarfarinaSalts: Warfarin sodium, Warfarin potassium
  2. Drug

    (R)-warfarin

    go.drugbank.com/drugs/DB08496
    Experimental

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

    Categories: Warfarin and isomers, Cytochrome P-450 SubstratesSynonyms: (+)-warfarin, (R)-warfarin
  3. Drug

    (S)-Warfarin

    go.drugbank.com/drugs/DB14055
    Investigational

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

    Categories: Warfarin and isomers, Cytochrome P-450 SubstratesSynonyms: (-)-Warfarin, (S)-Warfarin
  4. Drug

    S,R-Warfarin alcohol

    go.drugbank.com/drugs/DB08736
    Experimental

    Categories: Warfarin and isomersSynonyms: S,R-Warfarin alcohol
  5. Drug

    R,S-Warfarin alcohol

    go.drugbank.com/drugs/DB08735
    Experimental

    Categories: Warfarin and isomersSynonyms: R,S-Warfarin alcohol
  6. Drug

    Bisphosphocin Nu-3

    go.drugbank.com/drugs/DB16015
    Investigational

    Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).

    Synonyms: Nu-3, Bisphosphocin Nu-3
  7. Pathway

    Warfarin Action Pathway

    smpdb.ca/view/SMP0000268
    Drug action

    Warfarin is a drug part of the anticoagulant drug class, used to dissolve or break down blood clots. Warfarin inhibits vitamin K epoxide reductase complex subunit 1. … vitamin K epoxide reductase complex subunit 1 to become reduced vitamin K (phylloquinone), and then back to vitamin K1 2,3-epoxide continually through vitamin K-dependent gamma-carboxylase, but as warfarin

    Drugs: Warfarin · Phylloquinone · Calcium
  8. Pathway

    Warfarin Action Pathway (New)

    smpdb.ca/view/SMP0124982
    Drug action

    Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. … Warfarin is a [vitamin K] antagonist which acts to inhibit the production of vitamin K by inhibiting vitamin K epoxide reductase.

    Drugs: Warfarin · Phylloquinone · Calcium
  9. Target

    DNA polymerase nu

    go.drugbank.com/bio_entities/BE0016315
    TargetHumans

    DNA polymerase with very low fidelity that catalyzes considerable misincorporation by inserting dTTP opposite a G template, and dGTP opposite a T template (PubMed:16787914, PubMed:17118716). Is the least accurate of the DNA polymerase A ...

    Polypeptides: DNA polymerase nu
  10. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994.

    Mixtures: All Day Sinus and Cold D, All Day Sinus and Cold DCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates