Search

Displaying results 1 - 10 of 5365 in total
  1. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]

    Synonyms: Doxycycline, Anhydrous doxycyclineInternational brands: Nu-Doxycycline
  2. Drug

    Eucommia ulmoides bark

    go.drugbank.com/drugs/DB14259
    Investigational

    Eucommia ulmoides bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Du Zhong, Du Zhong Bark
  3. Drug

    Obexelimab

    go.drugbank.com/drugs/DB15032
    Investigational

    Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

    Synonyms: XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO 400-FOLD OVER NATIVE IGG) TO FCGRIIB)
  4. Pathway

    Doxycycline Action Pathway

    smpdb.ca/view/SMP0000291
    Drug action

    Doxycycline is a long-acting tetracycline derived from oxytetracycline. Like minocycline, it is lipophilic and can diffuse through the lipid bilayer of bacteria. … Doxycycline reversibly binds to the bacterial 30S ribosomal subunit and to a lesser extent the 50S subunit, blocking the binding of aminoacyl tRNA to the A site on the ribosome-RNA complex.

    Drugs: Doxycycline
  5. Pathway

    Doxycycline Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174526
    Metabolic

    Metabolites of Doxycycline are predicted with biotransformer.

    Drugs: Doxycycline · Mesoheme
  6. Drug

    Duvakitug

    go.drugbank.com/drugs/DB19444
    Investigational

    Duvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).

    Synonyms: Du vakitug, Immunoglobulin G1 [de-449-lysine], anti-(human tumor necrosis factor superfamily protein TNFSF15) (human monoclonal TEV-48574 γ1-chain), disulfide with human monoclonal TEV-48574 λ-chain, dimer
  7. Drug

    Coagulation factor VII human

    go.drugbank.com/drugs/DB13150
    ApprovedInvestigational

    Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.

    Synonyms: Factor VII, Factor VII humanMixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET
  8. Drug

    Meropenem

    go.drugbank.com/drugs/DB00760
    ApprovedInvestigational

    Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall ...

    Products: Meropenem Dr. F. Eberth 1 g Pulver zur Herstellung einer Injektionslösung oder Infusionslösung, Meropenem Dr. F. Eberth 500 mg Pulver zur Herstellung einer Injektionslösung oder Infusionslösung
  9. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [A193419] Few other antibiotics have been discovered that work via this alkylating mechanism, making mitomycin relatively unique in the space of microbiota-derived therapies.

    Products: Mutamycin Inj 5mg/vial, Mutamycin Inj 20mg/vial
  10. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Products: Thrombate III Pws IV 500iu/vial, Thrombate III Pws IV 1000iu/vial