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Displaying results 1 - 10 of 1723 in total
  1. Drug

    Modafinil

    go.drugbank.com/drugs/DB00745
    ApprovedInvestigational

    Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing pe...

    Products: Provigil, PROVIGIL
  2. Drug

    JNJ-27548547

    go.drugbank.com/drugs/DB15372
    Investigational

    JNJ-27548547 is under investigation in clinical trial NCT01705002 (Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.).

    Synonyms: PROMITIL
  3. Drug

    Eplerenone

    go.drugbank.com/drugs/DB00700
    ApprovedInvestigational

    Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone ...

    Products: INSPRA 50MG FTA, EPLERENON AL 25MG FTA
  4. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve e...

    Products: AMBRISENTAN AL 5MG FTA, AMBRISENTAN AL 10MG FTA
  5. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    FDA approved in 2009.

    Products: EFIENT 5MG FTA, EFIENT 10MG FTA
  6. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    [A2278,A2281] It was initially approved by the FDA in 2006.

    Products: DARUNASTA 600MG FTA, DARUNASTA 800MG FTA
  7. Drug

    Febuxostat

    go.drugbank.com/drugs/DB04854
    ApprovedInvestigational

    [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout who have an inadequate response or intolerance to [allopurinol … The manufacturer and the FDA advise health professionals to limit the use of febuxostat to second-line therapy in patients who have inadequate response or intolerance to allopurinol, and to avoid the use

    Products: ADENURIC 80MG FTA, ADENURIC 120MG FTA
  8. Drug

    Agomelatine

    go.drugbank.com/drugs/DB06594
    ApprovedInvestigational

    Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in ...

    Products: AGOMAVAL 25MG FTA, VALDOXAN 25MG FTA
  9. Drug

    Trospium

    go.drugbank.com/drugs/DB00209
    ApprovedInvestigational

    ._ and was granted FDA approval in 2007.[L6211]

    Products: SPASMED 15MG FTA, SPASMOLYT 45MG FTA
  10. Drug

    Ginkgo biloba

    go.drugbank.com/drugs/DB01381
    ApprovedInvestigationalNutraceutical

    _Ginkgo biloba_ is found in a number of homeopathic and over-the-counter herbal products and dietary supplements, but it has no approved therapeutic indications by regulatory bodies, such as the FDA, EMA

    Products: GINKGO AL 40 MG FTA, GINKGO AL 80 MG FTA