Displaying drugs 10876 - 10900 of 11635 in total
Volixibat
Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH.
Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Description: … Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... Inhibiting this enzyme results in a decrease of bile acids returning to the liver, which is helpful for ... granted fast track status by the Food and Drug Administration due to promising initial results and a …
Tecadenoson
Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. It is being developed by CV Therapeutics, Inc.
Investigational
Matched Description: … Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for …
LX6171
LX6171 is an oral drug candidate that was generated by Lexicon medicinal chemists and is being developed to treat disorders characterized by cognitive impairment, such as Alzheimer's disease, schizophrenia or vascular dementia.
Investigational
CG7870
CG7870 is an oncolytic virus therapy for prostate cancer. It is a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.
Investigational
Matched Description: … It is a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment …
NAV 1800
RIGScan CR49, a 125I-labelled CR monoclonal antibody directed against the tumour-associated antigen TAG-72, is undergoing development with Neoprobe for the intraoperative detection of metastatic colorectal cancer.
Investigational
Matched Description: … RIGScan CR49, a 125I-labelled CR monoclonal antibody directed against the tumour-associated antigen TAG …
Ponazuril
Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Vet approved
Matched Description: … Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for …
(5E,7E,9)-decatrien-2-one
An compound produced by Fomitopsis betulina, an edible fungus commonly called the birch polypore. Similar to (5Z,7E,9)-decatrien-2-one, it has a strong pineapple aroma.
Experimental
Matched Description: … Similar to [(5Z,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116] …
(5Z,7E,9)-decatrien-2-one
An compound produced by Fomitopsis betulina, an edible fungus commonly called the birch polypore. Similar to (5E,7E,9)-decatrien-2-one, it has a strong pineapple aroma.
Experimental
Matched Description: … Similar to [(5E,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116] …
2'-Fucosyllactose
2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy).
Investigational
Matched Description: … Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a …
HTPEP-001
HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-β). It is being investigated for the treatment of fibrosis.
Investigational
Matched Description: … HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta …
Survodutide
Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)).
Investigational
Matched Description: … Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide …
Mazdutide
Mazdutide is under investigation in clinical trial NCT06143956 (A Chronic Weight Management Master Protocol Study (LY900038) of Multiple Intervention-specific-appendices (Isas) in Adult Participants With Obesity or Overweight).
Investigational
Matched Description: … Mazdutide is under investigation in clinical trial NCT06143956 (A Chronic Weight Management Master Protocol …
Dazostinag
Dazostinag is under investigation in clinical trial NCT04420884 (A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors).
Investigational
Matched Description: … Dazostinag is under investigation in clinical trial NCT04420884 (A Study of Dazostinag as Single Agent …
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K.
Experimental
Matched Description: … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. ... These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group …
Gevokizumab
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. ... It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. …
Corticorelin
Corticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone,...
Investigational
Matched Description: … It is a type of neurohormone, also called hCRF. ... It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory …
Cytidine-5'-Diphosphate
Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate. [PubChem]
Experimental
Matched Description: … A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. …
REP8839
REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Investigational
Matched Description: … REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline …
MAHDL01
MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.
Investigational
Matched Description: … MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio …
Simmondsia chinensis seed
Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. …
Phellinus linteus mycelium
Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. …
Reynoutria multiflora root
Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. …
Indigofera tinctoria leaf
Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Bambusa vulgaris top
Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. …
Salvia miltiorrhiza root
Salvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Salvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 10876 - 10900 of 11635 in total