Displaying drugs 10901 - 10925 of 12071 in total
D-Treitol
A four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem]
Experimental
Matched Description: … A four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem] …
CZEN 002
CZEN-002 is a novel, non-azole anti-fungal synthetic octapeptide, derived from alpha-Melanocyte-Stimulating Hormone (a-MSH). CZEN-002 modulates inflammatory and immune responses. It has also been shown to kill Candida albicans (C. albicans), a single-celled fungal organism that causes a variety of infections, including vaginitis. This organism can invade tissues and produce fatal...
Investigational
Matched Description: … Hormone (a-MSH). ... a variety of infections, including vaginitis. ... It appears that CZEN-002 works on a receptor in yeast that has yet to be identified. …
VSF-173
VSF-173 is an oral small molecule. It is an oral compound that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a stimulant effect. It is developed for the treatment of excessive sleepiness. Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive...
Investigational
Matched Description: … Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive sleepiness. ... that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a …
Brifentanil
Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable...
Illicit
Matched Description: … Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. …
GSK-945237
GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237...
Investigational
Matched Description: … GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy ... Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and …
XL019
XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. An IND for XL019 was filed by Exelixis in May 2007.
Investigational
Matched Description: … XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. …
Succinobucol
AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary artery disease.
Investigational
Matched Description: … AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered …
Merimepodib
Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.
Investigational
Matched Description: … Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. …
LY2181308
LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung,...
Investigational
Matched Description: … LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. …
Erythritol
Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
Experimental
Matched Description: … Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. …
Eritoran
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Description: … Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). …
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. This compound belongs to the isoquinolines and derivatives. These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine. This medication is known to target mitogen-activated protein kinase 10.
Experimental
Matched Description: … ring fused to a pyridine ring and forming benzo[c]pyridine. ... 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. ... These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene …
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Description: … It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. …
IGN301
IGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis Y. Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. lung, intestinal, breast, prostate or ovarian cancers).
Investigational
Matched Description: … IGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis ... Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. …
YKP-1358
YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia. In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects.
Investigational
Matched Description: … YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity ... In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side …
5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole
5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole is a solid. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. This drug is known to target genome polyprotein.
Experimental
Matched Description: … 5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole is a solid. ... These are aromatic compounds containing an ether group substituted with a benzene ring. …
Thalagen
Thalagen is a branded product developed by San Rocco Therapeutics. It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene. It is being investigated for the treatment of beta-thalassemia.
Investigational
Matched Description: … Thalagen is a branded product developed by San Rocco Therapeutics. ... It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral …
DYNE-251
DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1). It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping.
Investigational
Matched Description: … DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that …
Rovazolac
Rovazolac is under investigation in clinical trial NCT03175354 (A Study in Subjects With Moderate Atopic Dermatitis).
Investigational
Matched Description: … Rovazolac is under investigation in clinical trial NCT03175354 (A Study in Subjects With Moderate Atopic …
NKTT-120
NKTT-120 is a recombinant humanized IgG1k monoclonal antibody to human invariant T cell receptor (iTCR).
Investigational
Matched Description: … NKTT-120 is a recombinant humanized IgG1k monoclonal antibody to human invariant T cell receptor (iTCR …
NGGT-002
NGGT-002 is a recombinant adeno-associated virus serotype 8 vector encoding human phenylalanine hydroxylase (PAH).
Investigational
Matched Description: … NGGT-002 is a recombinant adeno-associated virus serotype 8 vector encoding human phenylalanine hydroxylase …
LB-P8
LB-P8 is an investigational live biotherapeutic product consisting of a single bacterial strain (Leuconostoc citreum).
Investigational
Matched Description: … LB-P8 is an investigational live biotherapeutic product consisting of a single bacterial strain (_Leuconostoc …
Leflutrozole
Leflutrozole is under investigation in clinical trial NCT02908074 (A 6 Month Safety Extension Study of MBGS205).
Investigational
Matched Description: … Leflutrozole is under investigation in clinical trial NCT02908074 (A 6 Month Safety Extension Study of …
Oxyphenisatin
A laxative that undergoes enterohepatic circulation. It may cause jaundice.
Investigational
Withdrawn
Matched Description: … A laxative that undergoes enterohepatic circulation. It may cause jaundice. …
Itopride
Itopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.
Investigational
Matched Description: … Itopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions. …
Displaying drugs 10901 - 10925 of 12071 in total