Displaying drugs 1101 - 1125 of 15670 in total
Pinus ponderosa pollen
Pinus ponderosa pollen is the pollen of the Pinus ponderosa plant. Pinus ponderosa pollen is mainly used in allergenic testing.
Approved
Matched Description: … Pinus ponderosa pollen is mainly used in allergenic testing. …
Sarcobatus vermiculatus pollen
Sarcobatus vermiculatus pollen is the pollen of the Sarcobatus vermiculatus plant. Sarcobatus vermiculatus pollen is mainly used in allergenic testing.
Approved
Matched Description: … Sarcobatus vermiculatus pollen is mainly used in allergenic testing. …
Ustilago cynodontis
Ustilago cynodontis is a fungus which can provoke allergic reactions. Ustilago cynodontis extract is used in allergenic testing.
Approved
Matched Description: … Ustilago cynodontis extract is used in allergenic testing. ... Ustilago cynodontis is a fungus which can provoke allergic reactions. …
Rumex obtusifolius pollen
Rumex obtusifolius pollen is the pollen of the Rumex obtusifolius plant. Rumex obtusifolius pollen is mainly used in allergenic testing.
Approved
Matched Description: … Rumex obtusifolius pollen is mainly used in allergenic testing. …
Treprostinil
Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … 2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen- …
Matched Description: … [L41855,L41860] The first agent approved for the treatment of PAH was [epoprostenol], a synthetic prostacyclin ... Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension. ... However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Matched Description: … [L41855,L41860] The first agent approved for the treatment of PAH was [epoprostenol], a synthetic prostacyclin ... Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension. ... However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Mogamulizumab
Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma. Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically...
Approved
Investigational
Matched Description: … [L4168] It was approved for the same indications in Canada in June 2022. ... Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4 ... Approval in Japan was granted on April 30 2012 by the Japanese Ministry of Health, Labour and Welfare …
Crizotinib
Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumor (IMT). By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers...
Approved
Investigational
Matched Iupac: … 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine …
Matched Description: … Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase ... treating NSCLC in patients with this type of rearrangement. ... [A250785] Crizotinib was the first-in-class drug used to treat ALK-positive tumors. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Description: … Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase ... treating NSCLC in patients with this type of rearrangement. ... [A250785] Crizotinib was the first-in-class drug used to treat ALK-positive tumors. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Ambenonium
Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis.
Approved
Matched Iupac: … [(2-chlorophenyl)methyl](2-{[(2-{[(2-chlorophenyl)methyl]diethylazaniumyl}ethyl)carbamoyl]formamido}ethyl …
Matched Description: … Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis. …
Matched Description: … Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis. …
Brigatinib
Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Iupac: … 5-chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl] …
Matched Description: … pivotal player in the transformation of susceptible lung parenchyma. ... Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK ... selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a …
Matched Categories: … MATE 2 Inhibitors ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … pivotal player in the transformation of susceptible lung parenchyma. ... Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK ... selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a …
Matched Categories: … MATE 2 Inhibitors ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Rumex acetosella pollen
Rumex acetosella pollen is the pollen of the Rumex acetosella plant. Rumex acetosella pollen is mainly used in allergenic testing.
Approved
Matched Description: … Rumex acetosella pollen is mainly used in allergenic testing. …
Morus rubra pollen
Morus rubra pollen is the pollen of the Morus rubra plant. Morus rubra pollen is mainly used in allergenic testing.
Approved
Matched Description: … Morus rubra pollen is mainly used in allergenic testing. …
Holcus lanatus pollen
Holcus lanatus pollen is the pollen of the Holcus lanatus plant. Holcus lanatus pollen is mainly used in allergenic testing.
Approved
Matched Description: … Holcus lanatus pollen is mainly used in allergenic testing. …
Juglans nigra pollen
Juglans nigra pollen is the pollen of the Juglans nigra plant. Juglans nigra pollen is mainly used in allergenic testing.
Approved
Matched Description: … Juglans nigra pollen is mainly used in allergenic testing. …
Chloroquine
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Iupac: … 7-chloro-N-[5-(diethylamino)pentan-2-yl]quinolin-4-amine …
Matched Description: … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria ... [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Salts cas: … 3545-67-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Experimental Unapproved Treatments for COVID-19 …
Matched Description: … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria ... [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Salts cas: … 3545-67-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Experimental Unapproved Treatments for COVID-19 …
Glycerol phenylbutyrate
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Approved
Matched Iupac: … 1,3-bis[(4-phenylbutanoyl)oxy]propan-2-yl 4-phenylbutanoate …
Matched Description: … Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol ... Glycerol phenylbutyrate is a nitrogen-binding agent. …
Matched Description: … Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol ... Glycerol phenylbutyrate is a nitrogen-binding agent. …
Atoltivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … All three mAbs bind to a distinct portion of the GP1,2 glycoprotein and collectively provide ... of antibodies were important for therapeutic benefit in animal models of EBOV infection. ... role in combatting EBOV infection. …
Matched Categories: … Treatments for Ebola Virus Disease …
Matched Categories: … Treatments for Ebola Virus Disease …
Maftivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … All three mAbs bind to a distinct portion of the GP1,2 glycoprotein and collectively provide ... of antibodies were important for therapeutic benefit in animal models of EBOV infection. ... role in combatting EBOV infection. …
Matched Categories: … Treatments for Ebola Virus Disease …
Matched Categories: … Treatments for Ebola Virus Disease …
Dostarlimab
Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Description: … resulted in all twelve patients exhibiting a complete clinical response. ... A prospective phase II study in patients with mismatch repair-deficient locally advanced rectal cancer ... in the same month. …
Baricitinib
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Description: … [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with ... JAK inhibitor used for this indication in Europe. ... Baricitinib is a Janus kinase (JAK) inhibitor. …
Matched Categories: … MATE 2 Substrates with a Narrow Therapeutic Index ... Experimental Unapproved Treatments for COVID-19 ... MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …
Matched Description: … [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with ... JAK inhibitor used for this indication in Europe. ... Baricitinib is a Janus kinase (JAK) inhibitor. …
Matched Categories: … MATE 2 Substrates with a Narrow Therapeutic Index ... Experimental Unapproved Treatments for COVID-19 ... MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …
Opium
Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years ... Morphine is the most prevalent and principal alkaloid in opium, and it is responsible for most of the ... There is some legal production of opium in different countries for the obtention of alkaloids by extraction …
Sorghum halepense pollen
Sorghum halepense pollen is the pollen of the Sorghum halepense plant. Sorghum halepense pollen is mainly used in allergenic testing.
Approved
Matched Description: … Sorghum halepense pollen is mainly used in allergenic testing. …
Matched Mixtures name: … 3 Grass Mix …
Matched Mixtures name: … 3 Grass Mix …
Artemisia absinthium pollen
Artemisia absinthium pollen is the pollen of the Artemisia absinthium plant. Artemisia absinthium pollen is mainly used in allergenic testing.
Approved
Matched Description: … Artemisia absinthium pollen is mainly used in allergenic testing. …
Chenopodium botrys pollen
Chenopodium botrys pollen is the pollen of the Chenopodium botrys plant. Chenopodium botrys pollen is mainly used in allergenic testing.
Approved
Matched Description: … Chenopodium botrys pollen is mainly used in allergenic testing. …
Loxoprofen
Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. A transdermal preparation was approved for use in Japan in January 2006.
Approved
Matched Iupac: … 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid …
Matched Description: … A transdermal preparation was approved for use in Japan in January 2006. ... Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. ... , and as Oxeno in Argentina. …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Description: … A transdermal preparation was approved for use in Japan in January 2006. ... Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. ... , and as Oxeno in Argentina. …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Populus nigra pollen
Populus nigra pollen is the pollen of the Populus nigra plant. Populus nigra pollen is mainly used in allergenic testing.
Approved
Matched Description: … Populus nigra pollen is mainly used in allergenic testing. …
Displaying drugs 1101 - 1125 of 15670 in total