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Displaying drugs 3926 - 3950 of 4064 in total
Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Investigational
Matched Synonyms: … Antineoplaston as 2-1 component phenylacetylglutamine ... Antineoplaston as2-1 component phenylacetylglutamine …
Matched Iupac: … (2S)-4-carbamoyl-2-(2-phenylacetamido)butanoic acid …
Investigational
Investigational
A salt of alpha-lipoic acid and tromethamine; may be useful in treating vascular stress in patients with diabetes.
Investigational
Investigational
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Description: … It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct ... It consists of the first three short consensus domains of human complement receptor 1 (CR1), manufactured …
BT200 (Rondoraptivon pegol) is a PEGylated anti-von Willebrand factor (VWF) aptamer targeted against the VWF A1 domain. It is under investigation for the treatment of von Willebrand disease and hemophilia A.
Investigational
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Investigational
Matched Synonyms: … Arsenenous acid, sodium salt (1:1) …
G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG. These viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. MediGene uses these viruses, however, in a modified and "disarmed" form in order to...
Investigational
Matched Synonyms: … HSV-1 G207 …
Investigational
Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation and migration. The integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), as well...
Investigational
Investigational
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Synonyms: … Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen …
Experimental
Illicit
Matched Iupac: … (1S,5R,13S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7,9,11(18)-trien-10- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Experimental
Investigational
Matched Synonyms: … 6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol …
Matched Iupac: … 6,6,9-trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol …
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1- …
Nifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection).
Investigational
Matched Iupac: … 6-({2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl}amino)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … Ethyl (+)-(2s,3s)-2,3-epoxy-n-((s)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate …
Matched Iupac: … ethyl (2S,3S)-3-{[(1S)-3-methyl-1-[(3-methylbutyl)carbamoyl]butyl]carbamoyl}oxirane-2-carboxylate …
Displaying drugs 3926 - 3950 of 4064 in total