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Displaying drugs 6451 - 6475 of 7120 in total
Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
Investigational
Matched Iupac: … -3-yl]benzamide ... 3-[(1R,3R,5S)-8-{2-[(2S)-N-(cyclohexylmethyl)-2,3-dihydroxypropanamido]ethyl}-8-azabicyclo[3.2.1]octan …
Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin.
Vet approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... ]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-5-[(propylamino)methyl …
Muraglitazar (Bristol-Myers Squibb/Merck) is a new agent under investigation for the treatment of patients with type 2 diabetes. It belongs to a novel class of drugs that target the peroxisome proliferator-activated receptors, both alpha and gamma subtypes. In addition to improvements in blood glucose and hemoglobin A1c (HbA1c), muraglitazar treatment...
Investigational
Matched Iupac: … 2-{[(4-methoxyphenoxy)carbonyl]({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)amino}acetic …
ADX10061 is a potent, selective antagonist of the dopamine D1 receptor. It is developed by Addex Pharmaceuticals for the treatment of nicotine dependence.
Investigational
Matched Iupac: … (5S)-5-(2,3-dihydro-1-benzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol …
ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … (2S,3S)-3-(methoxymethyl)-3-methyl-17-oxa-7-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),11,13,15 …
Eltanexor is under investigation in clinical trial NCT02649790 (Study of the Safety, Tolerability and Efficacy of KPT-8602 in Patients With Relapsed/refractory Cancer Indications).
Investigational
Matched Iupac: … (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)prop-2-enamide …
Investigational
Matched Iupac: … (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate …
Pafuramidine, a prodrug of furamidine, currently has orphan status for Pneumocystis jiroveci pneumonia.
Investigational
Matched Iupac: … N-methoxy-4-{5-[4-(N-methoxycarbamimidoyl)phenyl]furan-2-yl}benzene-1-carboximidamide …
Matched Salts cas: … 837369-26-3
Mibampator has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … N-[(2R)-2-[4'-(2-methanesulfonamidoethyl)-[1,1'-biphenyl]-4-yl]propyl]propane-2-sulfonamide …
Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Withdrawn
Matched Iupac: … N-(4-ethoxyphenyl)acetamide …
Vanillyl alcohol has been used in trials studying the treatment of Smoking.
Investigational
Matched Iupac: … 4-(hydroxymethyl)-2-methoxyphenol …
Experimental
Vet approved
Matched Iupac: … 4-(dimethylamino)-2,2-diphenylpentanamide …
Matched Salts cas: … 20701-77-3
Sovaprevir has been investigated for the treatment of Hepatitis C, Chronic.
Investigational
Matched Iupac: … ]-2-ethenylcyclopropyl]-4-[(7-methoxy-2-phenylquinolin-4-yl)oxy]pyrrolidine-2-carboxamide ... (2S,4R)-1-[(2S)-2-tert-butyl-4-oxo-4-(piperidin-1-yl)butanoyl]-N-[(1R,2S)-1-[(cyclopropanesulfonyl)carbamoyl …
Investigational
Matched Iupac: … aluminium(3+) N-{3-[(2S,5S,8S,11R,14S,17S)-11-benzyl-5-(carbamoylmethyl)-8-(2-methylpropyl)-14,17-bis ... [3-(N-oxidoacetamido)propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexaazacyclooctadecan-2-yl]propyl} …
Investigational
Matched Iupac: … (2R,3R,5S)-2-{5-amino-2-oxo-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolan-3-yl acetate …
NRX-1074 has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Iupac: … -2-yl]formamido}-3-hydroxybutanamide ... (2S,3R)-2-{[(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-2-benzylpyrrolidin …
Risuteganib is under investigation in clinical trial NCT02348918 (Phase 2 Randomized Clinical Trial of Luminate® as Compared to Avastin® in the Treatment of Diabetic Macular Edema).
Investigational
Matched Iupac: … ]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid ... (2S)-1-[(2S,3R)-2-[(2R)-2-{2-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanamido]acetamido}-3-sulfopropanamido …
Imagabalin has been investigated in Generalized Anxiety Disorder.
Investigational
Matched Iupac: … (3S,5R)-3-amino-5-methyloctanoic acid …
Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.
Investigational
Matched Iupac: … (2R)-2-amino-3-(methylselanyl)propanoic acid …
Investigational
Matched Iupac: … 5-(3-methylphenoxy)-1,2-dihydropyrimidin-2-one …
Experimental
Illicit
Matched Iupac: … ethyl 1-{2-[(oxolan-2-yl)methoxy]ethyl}-4-phenylpiperidine-4-carboxylate …
Naphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO).
Investigational
Matched Iupac: … 2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol …
Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Investigational
Matched Iupac: … [(2R)-3-amino-2-fluoropropyl]phosphinic acid …
Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
Investigational
Matched Iupac: … N-hydroxy-N'-(pyridin-3-yl)octanediamide …
PD-0299685 is under investigation in clinical trial NCT00314964 (Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause).
Investigational
Matched Iupac: … (3S,5R)-3-(aminomethyl)-5-methyloctanoic acid …
Displaying drugs 6451 - 6475 of 7120 in total