Axelopran

DB12013InvestigationalSmall molecule

Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.

Mechanism: Pharmacologically active on Mu-type opioid receptor
Curator reviewed
Formula / weight: C₂₆H₃₉N₃O₄ · 457.615 g/mol (avg)
Code names: TD-1211

Resolves to

Compound

Structure

InChIKeyATLYLVPZNWDJBW-KIHHCIJBSA-NSMILESNC(=O)C1=CC=CC(=C1)[C@@H]1C[C@@H]2CC[C@H](C1)N2CCN(CC1CCCCC1)C(=O)[C@@H](O)CO

Targets

What you can answer from here — as of September 21, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

54Drug interactionsStructured to mechanism, not free text

8Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Axelopran, and which of those have an active Phase 3 trial?

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