Displaying drugs 3276 - 3300 of 3947 in total
Nomifensine
Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Synonyms: … 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Description: … Also withdrawn from the Canadian and UK markets. …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Description: … Also withdrawn from the Canadian and UK markets. …
ABT-751
ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
Investigational
Matched Synonyms: … N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide …
Matched Iupac: … N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzene-1-sulfonamide …
Matched Description: … ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell …
Matched Categories: … Amines …
Matched Iupac: … N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzene-1-sulfonamide …
Matched Description: … ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell …
Matched Categories: … Amines …
(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate
Experimental
Matched Name: … (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate …
(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol
Experimental
Matched Name: … (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol …
Matched Iupac: … (2R)-2-{[9-(propan-2-yl)-6-({[4-(pyridin-2-yl)phenyl]methyl}amino)-9H-purin-2-yl]amino}butan-1-ol …
Matched Iupac: … (2R)-2-{[9-(propan-2-yl)-6-({[4-(pyridin-2-yl)phenyl]methyl}amino)-9H-purin-2-yl]amino}butan-1-ol …
4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol
Experimental
Matched Name: … 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol …
Matched Iupac: … 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol …
Matched Iupac: … 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol …
5-phenyl-1H-indazol-3-amine
Experimental
Matched Name: … 5-phenyl-1H-indazol-3-amine …
Matched Iupac: … 5-phenyl-1H-indazol-3-amine …
Matched Iupac: … 5-phenyl-1H-indazol-3-amine …
7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
Experimental
Matched Name: … -5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid ... 7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
7-amino-2-tert-butyl-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidine-6-carboxamide
Experimental
Matched Name: … 7-amino-2-tert-butyl-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidine-6-carboxamide …
Matched Iupac: … 7-amino-2-tert-butyl-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidine-6-carboxamide …
Matched Iupac: … 7-amino-2-tert-butyl-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidine-6-carboxamide …
N-{3-[4-(3-aminopropyl)piperazin-1-yl]propyl}-3-(alpha-D-galactopyranosyloxy)-5-nitrobenzamide
Experimental
Matched Name: … N-{3-[4-(3-aminopropyl)piperazin-1-yl]propyl}-3-(alpha-D-galactopyranosyloxy)-5-nitrobenzamide …
1-Amino-2,3-Dihydroxy-5-Hydroxymethyl Cyclohex-5-Ene
Experimental
Matched Name: … 1-Amino-2,3-Dihydroxy-5-Hydroxymethyl Cyclohex-5-Ene …
Matched Iupac: … (1S,2S,3S)-3-amino-5-(hydroxymethyl)cyclohex-4-ene-1,2-diol …
Matched Iupac: … (1S,2S,3S)-3-amino-5-(hydroxymethyl)cyclohex-4-ene-1,2-diol …
2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol
Experimental
Matched Name: … 2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol …
Matched Iupac: … 2-({pyrido[2,1-h]purin-4-yl}amino)ethan-1-ol …
Matched Iupac: … 2-({pyrido[2,1-h]purin-4-yl}amino)ethan-1-ol …
5-[Bis-2(Chloro-Ethyl)-Amino]-2,4-Dintro-Benzamide
Experimental
Matched Name: … 5-[Bis-2(Chloro-Ethyl)-Amino]-2,4-Dintro-Benzamide …
Matched Iupac: … 5-[bis(2-chloroethyl)amino]-2,4-dinitrobenzamide …
Matched Iupac: … 5-[bis(2-chloroethyl)amino]-2,4-dinitrobenzamide …
Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid
Experimental
Matched Name: … Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid …
Matched Iupac: … 2-[1-carboxy-N-(naphthalen-1-yl)formamido]benzoic acid …
Matched Iupac: … 2-[1-carboxy-N-(naphthalen-1-yl)formamido]benzoic acid …
N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide
Experimental
Matched Name: … N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide …
Matched Iupac: … N-(4-phenoxyphenyl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
Matched Iupac: … N-(4-phenoxyphenyl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
Experimental
Matched Name: … 2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE …
TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL
Experimental
Matched Name: … TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL …
Matched Iupac: … (1S,2S)-2-amino-1,2,3,4-tetrahydronaphthalen-1-ol …
Matched Iupac: … (1S,2S)-2-amino-1,2,3,4-tetrahydronaphthalen-1-ol …
Idarubicin
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Synonyms: … (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside …
Matched Iupac: … (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12 …
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Iupac: … (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12 …
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Ivabradine
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Synonyms: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Description: … Although non-dihydropyridine calcium channel blockers and beta blockers also effectively lower heart ... is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and ... pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and …
Matched Categories: … metoprolol and ivabradine ... carvedilol and ivabradine …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Description: … Although non-dihydropyridine calcium channel blockers and beta blockers also effectively lower heart ... is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and ... pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and …
Matched Categories: … metoprolol and ivabradine ... carvedilol and ivabradine …
(2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL
Experimental
Matched Name: … (2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY …
Matched Iupac: … (2R)-1-(dimethylamino)-3-{4-[(6-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]phenoxy …
Matched Iupac: … (2R)-1-(dimethylamino)-3-{4-[(6-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]phenoxy …
METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE
Experimental
Matched Name: … ]AMINO}BENZOATE ... METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL …
Matched Iupac: … methyl 4-[({[(2R,5S)-5-[(2S)-2-(aminomethyl)pyrrolidine-1-carbonyl]pyrrolidin-2-yl]methyl}carbamoyl)amino …
Matched Iupac: … methyl 4-[({[(2R,5S)-5-[(2S)-2-(aminomethyl)pyrrolidine-1-carbonyl]pyrrolidin-2-yl]methyl}carbamoyl)amino …
6-Amino-4-Hydroxymethyl-Cyclohex-4-Ene-1,2,3-Triol
Experimental
Matched Name: … 6-Amino-4-Hydroxymethyl-Cyclohex-4-Ene-1,2,3-Triol …
Matched Iupac: … (1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol …
Matched Iupac: … (1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol …
N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
Experimental
Matched Name: … N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide …
Matched Iupac: … N-(4-chlorophenyl)-2-{[(pyridin-4-yl)methyl]amino}benzamide …
Matched Iupac: … N-(4-chlorophenyl)-2-{[(pyridin-4-yl)methyl]amino}benzamide …
5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile
Experimental
Matched Name: … 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile …
Matched Iupac: … 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile …
Matched Iupac: … 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile …
CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL
Experimental
Matched Name: … CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL …
Matched Iupac: … (1R,2S)-2-amino-1,2,3,4-tetrahydronaphthalen-1-ol …
Matched Iupac: … (1R,2S)-2-amino-1,2,3,4-tetrahydronaphthalen-1-ol …
3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL
Experimental
Matched Name: … 3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL …
Matched Iupac: … (2S,3S)-3-amino-4-phenylbutan-2-ol …
Matched Iupac: … (2S,3S)-3-amino-4-phenylbutan-2-ol …
Displaying drugs 3276 - 3300 of 3947 in total