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Displaying drugs 4251 - 4275 of 5288 in total
Experimental
Matched Name: … -5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid ... 7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo …
Matched Iupac: … yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetamido]-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5- …
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide ... hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. ... increases the risk of heart attack and stroke in patients with a history of heart disease. …
Matched Salts cas: … 125494-59-9 …
Matched Salts name: … Sibutramine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Serotonin and Noradrenaline Reuptake Inhibitors ... Norepinephrine, Serotonin, and Dopamine Reuptake Inhibitor Anorectic ... Drugs that are Mainly Renally Excreted …
Matched Products: … OBESTOPPOR 5 MG CAPSULAS ... Apo-sibutramine ... MESURA-ABL 10 MG CAPSULAS …
AV-101 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
Matched Synonyms: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid
Matched Name: … AV-101 …
Matched Iupac: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid
Matched Description: … AV-101 has been used in trials studying the treatment of Neuropathic Pain. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Investigational
Matched Synonyms: … Cholest-5-ene-3,7-diol, 3-(9z)-9-octadecenoate, (3.beta.,7.beta.)- …
Matched Iupac: … 11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy …
Matched Description: … DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase. …
Investigational
Matched Synonyms: … Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Synonyms: … 2-hydroxybenzoic acid 2-hydroxyethyl ester …
Matched Description: … Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory ... pains, and stiffness of the muscles, joints, and tendons [L2696]. ... It is found as an active ingredient and topical analgesic in patches used to provide relief for mild …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Investigational
Matched Synonyms: … )-(polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid
Experimental
Matched Name: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid
Matched Iupac: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid
Experimental
Matched Name: … 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID
Matched Iupac: … )acetic acid ... 2-(4-{2-[({[5-(pyridin-2-ylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}amino)methyl]-1H-imidazol-4-yl}phenoxy …
Experimental
Matched Name: … 4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide …
Matched Iupac: … 4-[(4-{imidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]benzene-1-sulfonamide …
Experimental
Matched Name: … 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE …
Matched Iupac: … 2-{[(4-chlorophenyl)methyl]amino}-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile …
Experimental
Matched Name: … 3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine …
Matched Iupac: … 3-methyl-N-[(pyridin-4-yl)methyl]imidazo[1,2-a]pyrazin-8-amine …
Miransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma).
Investigational
Matched Synonyms: … ARQ 092 ... ARQ-092 ... 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridin-2-amine …
Matched Iupac: … 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridin-2-amine …
Matched Description: … 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma). ... Miransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ
Investigational
Matched Synonyms: … hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo(d)(1,3)dioxol-5- …
Matched Iupac: … 3-{6-[(3S)-3-[(morpholin-4-yl)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-2H-1,3-benzodioxol-5- …
Investigational
Matched Synonyms: … 2-Propenamide, N-[4-[4-amino-5-[3-fluoro-4-[(4-methyl-2-pyrimidinyl)oxy]phenyl]-7-methyl-7H-pyrrolo[2,3 ... N-(4-(4-amino-5-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- ... N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2- yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin …
Matched Iupac: … N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
Matched Salts name: … Lirafugratinib hydrochloride
USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma Multiforme (GBM)).
Investigational
Matched Synonyms: … 6-{4-[l-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl}-N-(pyridin-4-yl)pyridine-2-carboxamide …
Matched Iupac: … 6-{4-[1-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl}-N-(pyridin-4-yl)pyridine-2-carboxamide …
Matched Description: … USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in ... Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma …
Investigational
Matched Synonyms: … (1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-((2r)-3-((2-(4-chloro-3-fluorophenyl)-1,1-dimethylethyl ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl(1,1'-biphenyl)-4-carboxylic acid ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl)-3-methyl-1,1'-biphenyl-4-carboxylic acid
Matched Iupac: … fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic acid
Matched Salts cas: … 1214922-52-7 …
Matched Salts name: … Encaleret sulfate
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl ... ]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid
Matched Iupac: … dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Matched Description: … It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and
Matched Salts name: … Mezlocillin sodium ... Mezlocillin sodium monohydrate …
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … gram-negative and gram-positive bacteria. ... A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most …
Matched Categories: … norfloxacin and tinidazole ... norfloxacin and metronidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ava-norfloxacin ... NORFLOXACINA ABC ... NORFLOXACIN AL 400MG …
Experimental
Matched Name: … octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside …
Matched Iupac: … (2S,3S,4S,6S)-6-{[(2R,3R,4S,5R,6R)-4-amino-5-hydroxy-6-(hydroxymethyl)-2-(octyloxy)oxan-3-yl]oxy}-2-methyloxane …
Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Approved
Matched Description: … ovarian cancer), lymphomas and germ cell tumors. ... It was the first member of its class, which now also includes carboplatin and oxaliplatin. ... to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted ... OCT2 Substrates with a Narrow Therapeutic Index …
Matched Products: … Platinol-AQ ... Platinol AQ Inj 1mg/ml ... CISPLATINO 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Experimental
Matched Name: … 5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE …
Matched Iupac: … 5-({4'-amino-1'-ethyl-5',8'-difluoro-1'H-spiro[piperidine-4,2'-quinazolin]-1-yl}carbonyl)-3,4-dihydropyridine …
Experimental
Matched Name: … (2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine …
Matched Iupac: … (2S)-1-(7aH-indol-3-yl)-3-{[5-(2H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
Experimental
Matched Name: … N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine …
Matched Iupac: … N2-(1H-1,3-benzodiazol-5-yl)-N4-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine …
Displaying drugs 4251 - 4275 of 5288 in total