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Displaying drugs 1901 - 1908 of 1908 in total

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … mental health conditions including schizophrenia and bipolar disorder. ... carries lesser activity at several off-targets which may responsible for some of its undesirable effects ... D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical …
Matched Products: … RISPERDAL CONSTA FOR INJECTION 25 mg/vial ... RISPERDAL CONSTA FOR INJECTION 37.5 mg/vial …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Systemic Use ... Antifungals for Dermatological Use …
Matched Products: … Lamisil AT for Jock Itch …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … duration of action and relief from pain or withdrawal symptoms for upwards of 24-36 hours. ... used for the treatment of severe pain. ... who require larger and more frequent doses. …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine HCl and Naloxone HCl …
Matched Products: … TEMGESIC FORTE SUBLI 0.4MG …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … effective treatment for erectile dysfunction and since its formal approval for medical use in the public ... it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth …
Matched Products: … Sildenafil for Oral Suspension …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … , and panic disorder in Canada for many years. ... headaches,[A413,A177229] for reduction of vasomotor symptoms associated with menopause,[A177238] and ... Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Antidepressive Agents Indicated for Depression …
Matched Products: … VENLEX FORTE XR CAPSULES 150MG …

Valsartan

Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... Valsartan is commonly used for the management of hypertension, heart failure, and Type 2 Diabetes-associated ... [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension …
Matched Mixtures name: … CODIOVAN FORTE 160/25MG ... COTAREG FORTE 160MG/25MG ... CODIOVAN FORTE 160MG/25MG …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... valsartan and nebivolol ... valsartan and diuretics ... valsartan and aliskiren ... Angiotensin II Antagonists and Diuretics …
Matched Products: … DIOVAN 320MG FORTE FILMTAB …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea ... can also contribute to dose optimization and reduced adverse effects. ... is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution …
Matched Categories: … Ophthalmological and Otological Preparations ... Protein Synthesis Inhibitors ... Antibiotics for Topical Use ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … BIOGEN FORTE …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility ... and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Olanzapine for Injection …
Displaying drugs 1901 - 1908 of 1908 in total