Displaying drugs 226 - 250 of 554 in total
Ofranergene obadenovec
Ofranergene obadenovec is under investigation in clinical trial NCT01229865 (Safety and Efficacy of VB-111 in Subjects With Advanced Differentiated Thyroid Cancer).
Investigational
Matched Synonyms: … GENETIC VECTOR CONTAINING TUMOR VASCULAR ENDOTHELIUM-DIRECTED CHIMERIC FAS ANTIGEN GENE …
AGRO100
AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.
Pre-clinical testing demonstrates that...
Investigational
Matched Synonyms: … Nucleic acid aptamer binding to tumor cell nucleon …
Matched Description: … binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor ... Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor …
Matched Description: … binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor ... Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor …
OSE-2101
Investigational
Matched Synonyms: … 10 synthetic peptides targeting 5 tumor associated antigens …
Dapirolizumab pegol
Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … Immunoglobulin fab' g1-kappa pegylated, anti-(homo sapiens cd40lg (cd40 ligand, cd40l, tumor necrosis ... factor ligand superfamily member 5, tnfsf5, tumor necrosis factor related activation protein, trap, …
Boserolimab
Investigational
Matched Synonyms: … Immunoglobulin G1-kappa, anti-(homo sapiens CD27 (TNFRSF7, tumor necrosis factor receptor (TNFR) superfamily …
Myb34.5
Investigational
Matched Synonyms: … Herpes simplex type 1 virus containing cellular B-myb gene as tumor-specific promoter …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily ... Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen …
Axalimogene filolisbac
Axalimogene filolisbac is under investigation in clinical trial NCT02853604 (Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer).
Investigational
Matched Synonyms: … Live, attenuated listeria monocytogenes bacteria, expressing human papilloma virus type 16-e7 tumor antigen …
Telitacicept
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS ... 13-118-tumor necrosis factor receptor superfamily protein tnfrsf13b (human extracellular domain fragment …
Exlinkibart
Investigational
Matched Synonyms: … Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … (human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor …
Quisovalimab
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Tasadenoturev
Investigational
Matched Synonyms: … Tumor-selective delta-24 ,rgd modified adenovirus serotype 5 …
Cinrebafusp alfa
Investigational
Matched Synonyms: … FUSED ON BOTH HEAVY CHAINS (1-447, 1''-447'') VIA A (G4S)3 LINKER (448-462, 448''-462'') TO A CD137 (TUMOR …
Kisspeptin-10
Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men).
Investigational
Matched Categories: … Genes, Tumor Suppressor ... Tumor Suppressor Proteins …
AMGN-0007
Recombinant osteoprotegerin (AMGN-0007) is a recombinant OPG construct developed as a potential therapeutic agent in the treatment of bone disease.
Investigational
Matched Categories: … Tumor Necrosis Factor Decoy Receptors …
Banoxantrone
Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic to, hypoxic cells in tumours. It has been shown to work synergistically with fractionated radiation to significantly delay growth of tumours compared to administration of either banoxantrone or radiation alone. Banoxantrone was also efficacious in...
Investigational
Afelimomab
Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Investigational
Matched Categories: … Tumor Necrosis Factor Blockers ... Tumor necrosis factor alpha (TNF-alpha) inhibitors …
TAK-448
TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Investigational
Matched Categories: … Tumor Suppressor Proteins …
TAK-715
TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis).
Investigational
Matched Categories: … Tumor Necrosis Factor Blockers …
Displaying drugs 226 - 250 of 554 in total