Displaying drugs 2576 - 2600 of 2973 in total
2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE
Experimental
Matched Name: … 2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE …
Matched Iupac: … 2-(carboxymethyl)-1,3,3-trioxo-1H,2H-3lambda6-naphtho[1,2-d][1,2]thiazole-4-carboxylic acid …
Matched Iupac: … 2-(carboxymethyl)-1,3,3-trioxo-1H,2H-3lambda6-naphtho[1,2-d][1,2]thiazole-4-carboxylic acid …
(8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid
Experimental
Matched Name: … (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid …
Matched Iupac: … ,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7-carboxylic acid …
Matched Iupac: … ,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7-carboxylic acid …
[(2S)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl]acetic acid
Experimental
Matched Name: … [(2S)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl]acetic acid …
Matched Iupac: … 2-[(2S)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl]acetic acid …
Matched Iupac: … 2-[(2S)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl]acetic acid …
Trolamine
Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Synonyms: … nitrilo-2,2',2''-triethanol …
Matched Description: … Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant ... and hair conditioning products. ... It is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin …
Matched Mixtures name: … SUNHEAL Milia Spot Treatment …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Description: … Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant ... and hair conditioning products. ... It is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin …
Matched Mixtures name: … SUNHEAL Milia Spot Treatment …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
SEL-24
Investigational
Matched Synonyms: … 1h-benzimidazole, 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)- ... 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)-1h-benzimidazole ... 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1h-1,3-benzimidazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …
MDX-1303
MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins known as the anthrax protective antigen.
Investigational
Matched Synonyms: … ANTI-(BACILLUS ANTHRACIS ANTHRAX PROTECTIVE ANTIGEN) (HUMAN MONOCLONAL 5E8 HEAVY CHAIN), DISULFIDE WITH …
Matched Description: … inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and …
Matched Description: … inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and …
Ozanezumab
Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH …
Matched Description: … has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lemzoparlimab
Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4(228-proline), anti-(human cd47 antigen) (human monoclonal tj011133 .gamma.4-chain), disulfide with …
Matched Description: … and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without ... Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and ... Venetoclax in Participants With Myelodysplastic Syndrome). …
Matched Description: … and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without ... Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and ... Venetoclax in Participants With Myelodysplastic Syndrome). …
Xeligekimab
Xeligekimab is under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With Uncontrolled Seasonal Allergic Rhinitis.).
Investigational
Matched Synonyms: … g4 (235-proline), anti-(human interleukin 17a) (human monoclonal gr1501 .gamma.4-chain), disulfide with …
Matched Description: … under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With …
Matched Description: … under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With …
Teprotumumab
Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016 and was approved by the FDA...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with …
Matched Description: … disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and ... tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive ... Thyroid eye disease is a potentially debilitating complication of Graves' Disease involving inflammation and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and ... tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive ... Thyroid eye disease is a potentially debilitating complication of Graves' Disease involving inflammation and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and ... Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and ... Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Osemitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN-MUS MUSCULUS MONOCLONAL TST001 .GAMMA.1-CHAIN), DISULFIDE WITH …
Pulocimab
Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).
Investigational
Matched Synonyms: … human vascular endothelial growth factor receptor 2) (human monoclonal ak109 .gamma.1-chain), disulfide with …
Matched Description: … Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and …
Matched Description: … Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and …
Cinrebafusp alfa
Investigational
Matched Synonyms: … ) (HUMAN-MUS MUSCULUS MONOCLONAL PRS-343 .GAMMA.4-CHAIN) FUSION PROTEIN PEPTIDE (SYNTHETIC 15-AMINO ACID ... LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU …
Trimethyllysine
Experimental
Matched Synonyms: … (S)-2-amino-6-(trimethylammonio)hexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Fidrisertib
Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2 …
Ebola Zaire vaccine (live, attenuated)
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) ... Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein …
Matched Description: … [L10866] In 2014, Merck Inc. signed a licensing agreement with NewLink for further development and marketing ... and external bleeding. ... These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal …
Matched Description: … [L10866] In 2014, Merck Inc. signed a licensing agreement with NewLink for further development and marketing ... and external bleeding. ... These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal …
Andarine
Andarine is a non-steroidal selective androgen receptor modulator.
Experimental
Matched Synonyms: … (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Iupac: … (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
SR-9011
SR-9011 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues .
Experimental
Matched Synonyms: … 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Meperidine
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … with morphine and are of shorter duration. ... that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids ... pethidine, combinations with psycholeptics …
Matched Products: … Demerol 50 mg/ml (multiple Dose With Metacresol As Preservative) …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids ... pethidine, combinations with psycholeptics …
Matched Products: … Demerol 50 mg/ml (multiple Dose With Metacresol As Preservative) …
Spesolimab
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain), disulfide with …
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and ... was finally approved in December 2022 for the treatment of flares in adult patients with generalized …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and ... was finally approved in December 2022 for the treatment of flares in adult patients with generalized …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Rinucumab
Rinucumab is under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … (human platelet-derived growth factor receptor~) (human monoclonal regn2176 heavy chain), disulfide with …
Matched Description: … under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants With …
Matched Description: … under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants With …
Ozekibart
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Synonyms: … anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) fusion protein with ... peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor 5) (human-Lama glama …
Budesonide
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532]
Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions ... [L10598] It is also available in a combination product with [formoterol].[L10619] …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … BUDESONID ACIS NASENSPRAY …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … BUDESONID ACIS NASENSPRAY …
Nitenpyram
Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death.
Experimental
Vet approved
Matched Synonyms: … (1E)-N-((6-chloro-3-pyridinyl)methyl)-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine …
Matched Description: … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of ... It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the …
Matched Description: … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of ... It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the …
Displaying drugs 2576 - 2600 of 2973 in total