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Displaying drugs 2876 - 2900 of 3123 in total
Ciglitazone
Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to the market....
Experimental
Matched Description: … It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo. …
ADH-1
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Description: … found that N-cadherin is expressed in greater amounts, making it an important target for developing anti-cancer …
Imidocarb
Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
Vet approved
Matched Categories: … Anti-Infective Agents …
Uprifosbuvir
Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and GT2 Infection (MK-3682-011)).
Investigational
Matched Categories: … Anti-Infective Agents …
Radavirsen
Radavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza).
Investigational
Matched Categories: … Anti-Infective Agents …
Donanemab
Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - pyroglutamate Aβ - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD). It works by inducing microglial-mediated clearance of existing Aβ...
Investigational
Matched Categories: … Anti-Dementia Drugs …
Feprazone
Experimental
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Nitroaspirin
Nitroaspirin has been investigated for the treatment of Intermittent Claudication.
Investigational
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Sitafloxacin
Experimental
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Difenpiramide
Experimental
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Evening primrose oil
Evening primrose oil comes from the extraction from Oenothera biennis seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. In its composition it presents some fatty acids such as DB00132 and DB13854. Evening primrose oil has been filled for the FDA by Humanetics Corporation...
Investigational
Nutraceutical
Matched Categories: … Anti-Inflammatory Agents …
Doxofylline
Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … The anti-asthmatic effects of doxophylline are mediated by other mechanisms, primarily through inhibiting …
Matched Categories: … Anti-Asthmatic Agents …
Matched Categories: … Anti-Asthmatic Agents …
Misonidazole
Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Investigational
Matched Categories: … Anti-Infective Agents …
Ingavirin
Ingavirin has been used in trials studying the treatment of Influenza and Common Cold.
Investigational
Matched Categories: … Anti-Infective Agents …
Sinefungin
Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.
Experimental
Matched Categories: … Anti-Infective Agents …
Adipiplon
Adipiplon is an nonbenzodiazepine anxiolytic developed by Neurogen Corporation. It is known by the standardized identifier NG2-73.
Investigational
Matched Categories: … Anti-Anxiety Agents …
Tropatepine
Tropatepine has been used in France for its antiparkinsons activities .
Experimental
Matched Categories: … Anti-Parkinson Drugs …
Fenspiride
Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as...
Experimental
Matched Categories: … Anti-Asthmatic Agents …
Displaying drugs 2876 - 2900 of 3123 in total