Displaying drugs 2901 - 2925 of 7208 in total
Ad-SGE-REIC
Investigational
X-165
Investigational
Matched Synonyms: … (R)-N-(1-(1-(1H-indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4,5]decan-8-yl)-3-methyl-1-oxobutan ... -2-yl)-2-fluoro-5-(trifluoromethyl)benzamide …
2'-deoxyuridine 5'-alpha,beta-imido-diphosphate
Experimental
Matched Synonyms: … 2'-Deoxy-5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]uridine …
Matched Name: … 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate …
Matched Iupac: … [({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Name: … 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate …
Matched Iupac: … [({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
ICG-001
Investigational
Matched Synonyms: … -5-ylmethyl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide ... (6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-4,7-dioxo-2-((3-(pyridin-2-yl)isoxazol-5-yl)methyl)-8-(quinolin …
Recombinant neuroglobin
Investigational
SB-743921
Investigational
Matched Iupac: … N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl]-4-methylbenzamide …
TAK-751S
TAK-751S is a synthetic analog of Shiga toxin (Stx) receptor, Gb3, produced by enterohemorrhagic Escherichia coli.
Investigational
UX701
Investigational
4,5,6,7-Tetrachloro-3h-Isobenzofuran-1-One
Experimental
S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
Experimental
KC706
KC706 is a novel anti-inflammatory drug that works by inhibiting the activity of p38 MAP kinase. KC706 holds potential to treat inflammatory conditions such as rheumatoid arthritis, psoriasis, inflammatory bowel disease and cardiovascular disease.
Investigational
SB-705498
SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
Investigational
Matched Iupac: … 1-(2-bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-3-yl]urea …
CP-724714
CP-724,714 has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasm Metastasis.
Investigational
Aramchol
Aramchol has been used in trials studying the treatment of HIV, Gallstones, Fatty Liver, Metabolic Syndrome, and Nonalcoholic Steatohepatitis, among others.
Investigational
Matched Iupac: … (4R)-4-[(1S,2S,5S,7S,9R,10R,11S,14R,15R,16S)-9,16-dihydroxy-5-icosanamido-2,15-dimethyltetracyclo[8.7.0.0 …
5'-S-methyl-5'-thioadenosine
Experimental
Matched Synonyms: … 5'-Deoxy-5'-(methylthio)adenosine ... 9-(5-S-methyl-5-thio-β-D-ribofuranosyl)-9H-purin-6-amine ... 5-Methylthioadenosine …
Matched Name: … 5'-S-methyl-5'-thioadenosine …
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …
Matched Name: … 5'-S-methyl-5'-thioadenosine …
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …
Nesolicaftor
Nesolicaftor (PTI-428) is under investigation in clinical trial NCT03258424 (Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background Therapy).
Investigational
Matched Synonyms: … N-(trans-3-(5-((R)-1-hydroxyethyl)-1,3,4-oxadiazol-2-yl)cyclobutyl)-3-phenylisoxazole-5-carboxamide …
Matched Iupac: … 3-phenyl-N-[(1r,3r)-3-{5-[(1R)-1-hydroxyethyl]-1,3,4-oxadiazol-2-yl}cyclobutyl]-1,2-oxazole-5-carboxamide …
Matched Iupac: … 3-phenyl-N-[(1r,3r)-3-{5-[(1R)-1-hydroxyethyl]-1,3,4-oxadiazol-2-yl}cyclobutyl]-1,2-oxazole-5-carboxamide …
Hydroxydione
Hydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic.
Investigational
Withdrawn
Matched Iupac: … 3bR,5aR,9aS,9bS,11aS)-1-(2-hydroxyacetyl)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7- …
XL784
XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied...
Investigational
XL765
XL765 is an orally available small molecule that has been shown in preclinical studies to selectively inhibit the activity of phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR). It is being developed by Exelixis, Inc.
Investigational
CP-744809
Experimental
Matched Iupac: … 6-[(5-chloro-3-methyl-1-benzofuran-2-yl)sulfonyl]-2,3-dihydropyridazin-3-one …
SB-773812
SB-773812 is under investigation in clinical trial NCT00259870 (SB-773812 Administered in Adults With Schizophrenia).
Investigational
Matched Iupac: … 7-{4-[(4-chlorophenyl)methoxy]benzenesulfonyl}-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine …
PLN-74809
PLN-74809 is a small-molecule that dually inhibits both αvβ6 and αvβ1 to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) . The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in...
Investigational
BI-765063
BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα).
Investigational
Displaying drugs 2901 - 2925 of 7208 in total