Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 2901 - 2925 of 3553 in total
Experimental
Matched Name: … (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID
Matched Iupac: … (2E)-3-[2-(oct-1-yn-1-yl)phenyl]prop-2-enoic acid
Experimental
Matched Synonyms: … (2S)-2-[3-[(2-bromoacetyl)amino]propanoylamino]-3-hydroxypropanoyl]amino]ethyl]anilino]-2-oxoacetic acid
Matched Name: … N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide …
Matched Iupac: … [(4-{2-[(2S)-2-[3-(2-bromoacetamido)propanamido]-3-hydroxypropanamido]ethyl}phenyl)carbamoyl]formic acid
Investigational
Matched Synonyms: … 153sm-1,4,7,10-tetraazacyclododecane-1,4,7,10- tetramethylene-phosphonic acid
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … -1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic acid ... Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' ... oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid
Matched Iupac: … dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornase alpha
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … 1h-pyrazol-4-yl)-1-((6-(1-methyl-1h-pyrazol-4-yl)imidazo(1,2-a)pyridin-3-yl)sulfonyl)-1h-pyrazolo(4,3-b)pyridine
Matched Description: … Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety …
Investigational
Matched Synonyms: … Spiro(cyclohexane-1,5'(7'h)-furo(3,4-b)pyridine)-4-carboxamide, 2'-methoxy-n-methyl-7'-oxo-n-(2-(1-piperidinyl …
Matched Iupac: … 1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-[2-(piperidin-1-yl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances …
Experimental
Matched Synonyms: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Synonyms: … (L)-2-Amino-3-(carboxymethylthio)propionic acid
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid
Matched Description: … Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... viruses and bacteria in thick bronchial mucus. ... by physicians in France and Italy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Investigational
Withdrawn
Matched Synonyms: … Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
Experimental
Matched Name: … 5-(Hydroxy-Methyl-Amino)-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5R)-5-[hydroxy(methyl)amino]-3-methylpyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid
Experimental
Matched Name: … 2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
Matched Iupac: … (3R)-2-{[1,1'-biphenyl]-4-sulfonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Experimental
Matched Name: … L-2-amino-4-methoxy-cis-but-3-enoic acid
Matched Iupac: … (2S,3Z)-2-amino-4-methoxybut-3-enoic acid
Experimental
Matched Name: … 3-[Isopropyl(4-Methylbenzoyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid
Matched Iupac: … 5-phenyl-3-[N-(propan-2-yl)4-methylbenzamido]thiophene-2-carboxylic acid
Experimental
Matched Name: … 3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid
Matched Iupac: … 3-{[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]oxy}propanoic acid
Experimental
Matched Name: … (3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid
Matched Iupac: … (2R,3S)-2-ethyl-3-(4-methylbenzenesulfonamido)butanedioic acid
Experimental
Matched Name: … (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID
Matched Iupac: … 2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}phenoxy)acetic acid
Experimental
Matched Name: … 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID
Matched Iupac: … 2',4'-dichloro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Experimental
Matched Name: … (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
Matched Iupac: … (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
Experimental
Matched Name: … (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
Matched Iupac: … (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
Displaying drugs 2901 - 2925 of 3553 in total