Displaying drugs 3226 - 3250 of 4000 in total
BI-187004
Investigational
Matched Synonyms: … 1h-indeno(2,1-b)pyridine-6-carbonitrile, 1-(1h-benzimidazol-6-ylcarbonyl)-2,3,4,4a,9,9a-hexahydro-, ( …
Midodrine
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Synonyms: … DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid ... 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide …
Matched Description: … An ethanolamine derivative that is an adrenergic alpha agonist. …
Matched Salts name: … Midodrine hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Midodrine Hydrochloride ... Midodrine hydrochloride …
Matched Description: … An ethanolamine derivative that is an adrenergic alpha agonist. …
Matched Salts name: … Midodrine hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Midodrine Hydrochloride ... Midodrine hydrochloride …
Dextrorphan
Experimental
Matched Synonyms: … Levorphanol D-form ... d-3-hydroxy-N-methylmorphinan …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Salts name: … Naratriptan hydrochloride …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Monoamine Oxidase A Substrates …
Matched Products: … Naratriptan Hydrochloride …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Monoamine Oxidase A Substrates …
Matched Products: … Naratriptan Hydrochloride …
Apramycin
Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans.
Experimental
Vet approved
Matched Synonyms: … 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo ... -1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine ... -(methylamino)pyrano(3,2-b)pyran-2α-yl)-2-deoxy-D-streptamine …
Matched Description: … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria ... Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted …
Matched Description: … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria ... Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted …
Telacebec
Investigational
Matched Synonyms: … 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine …
Fentanyl
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone.
Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like [morphine] and …
Matched Salts name: … Fentanyl hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … FENTANYL BETA 100UG/H MATR ... FENTANYL BETA 12UG/H MATRI ... FENTANYL BETA 25UG/H MATRI …
Matched Salts name: … Fentanyl hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … FENTANYL BETA 100UG/H MATR ... FENTANYL BETA 12UG/H MATRI ... FENTANYL BETA 25UG/H MATRI …
D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide
Experimental
Matched Synonyms: … D-pyridoxyl-N,O-cycloserylamide-5-monophosphate …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … 5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic acid …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … 5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic acid …
S-octylglutathione
Experimental
Matched Synonyms: … L-γ-Glutamyl-S-octyl-D-cysteinylglycine …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(octylsulfanyl)ethyl]carbamoyl}butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(octylsulfanyl)ethyl]carbamoyl}butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nebularine
Experimental
Matched Synonyms: … N-D-Ribosylpurine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
KRN-7000
KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With Hematological Malignancies Undergoing AHSCT.
Investigational
Matched Synonyms: … 1-O-(α-D-galactopyranosyl)-N-hexacosanoylphytosphingosine …
Matched Description: … Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and …
Matched Description: … Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and …
4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide
Experimental
Matched Name: … 4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl …
Matched Iupac: … hex-1-en-3-yl]-2-({hydroxy[4-(morpholin-4-yl)piperidin-1-yl]methylidene}amino)-3-phenylpropanimidic acid …
Matched Iupac: … hex-1-en-3-yl]-2-({hydroxy[4-(morpholin-4-yl)piperidin-1-yl]methylidene}amino)-3-phenylpropanimidic acid …
(2s)-2-[(5-Benzofuran-2-Yl-Thiophen-2-Ylmethyl)-(2,4-Dichloro-Benzoyl)-Amino]-3-Phenyl-Propionic Acid
Experimental
Matched Name: … (2s)-2-[(5-Benzofuran-2-Yl-Thiophen-2-Ylmethyl)-(2,4-Dichloro-Benzoyl)-Amino]-3-Phenyl-Propionic Acid …
Matched Iupac: … -(N-{[5-(1-benzofuran-2-yl)thiophen-2-yl]methyl}-1-(2,4-dichlorophenyl)formamido)-3-phenylpropanoic acid …
Matched Iupac: … -(N-{[5-(1-benzofuran-2-yl)thiophen-2-yl]methyl}-1-(2,4-dichlorophenyl)formamido)-3-phenylpropanoic acid …
1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE
Experimental
Matched Name: … 1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE …
2-[(1R)-1-carboxy-2-naphthalen-1-ylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid
Experimental
Matched Name: … 2-[(1R)-1-carboxy-2-naphthalen-1-ylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
Matched Iupac: … 2-[(1R)-1-carboxy-2-(naphthalen-1-yl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
Matched Iupac: … 2-[(1R)-1-carboxy-2-(naphthalen-1-yl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID
Experimental
Matched Name: … {3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID …
Matched Iupac: … 2-{3-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}acetic acid …
Matched Iupac: … 2-{3-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}acetic acid …
3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID
Experimental
Matched Name: … 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID …
Matched Iupac: … (3S)-3-[(2R)-6-[(8-hydroxyquinolin-2-yl)formamido]-2-(thiophen-2-yl)hexanamido]-4-oxobutanoic acid …
Matched Iupac: … (3S)-3-[(2R)-6-[(8-hydroxyquinolin-2-yl)formamido]-2-(thiophen-2-yl)hexanamido]-4-oxobutanoic acid …
Chlorprothixene
Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
Approved
Experimental
Investigational
Withdrawn
Matched Synonyms: … Alpha-Chlorprothixene …
Matched Description: … and alpha1 adrenergic receptors. ... Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic …
Matched Salts name: … Chlorprothixene hydrochloride …
Matched Categories: … Dopamine D2 Receptor Antagonists …
Matched Description: … and alpha1 adrenergic receptors. ... Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic …
Matched Salts name: … Chlorprothixene hydrochloride …
Matched Categories: … Dopamine D2 Receptor Antagonists …
Lofexidine
Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment...
Approved
Investigational
Matched Synonyms: … 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline …
Matched Description: … Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Salts name: … Lofexidine hydrochloride …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Description: … Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Salts name: … Lofexidine hydrochloride …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Interferon alfa-n1
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Synonyms: … Interferon alpha-n1 (INS) …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Etryptamine
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Synonyms: … alpha-ethyltryptamine …
Matched Description: … In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was ... αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine ... the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and …
Matched Salts name: … Alpha-ethyltryptamine acetate …
Matched Description: … In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was ... αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine ... the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and …
Matched Salts name: … Alpha-ethyltryptamine acetate …
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … alpha-Chymotrypsin …
Matched Description: … Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and ... Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin ... It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and ... Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin ... It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Displaying drugs 3226 - 3250 of 4000 in total