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Displaying drugs 3501 - 3525 of 4257 in total

2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER

Experimental
Matched Name: … 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER …

N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE

Experimental
Matched Name: … N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE …
Matched Iupac: … N-ethyl-3-methyl-N-(propan-2-yl)-5-[(2S)-2-[(pyridin-4-yl)amino]propoxy]benzamide …

N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE

Experimental
Matched Name: … N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE …
Matched Iupac: … benzyl N-[(1S)-1-{[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamoyl}-3-methylbutyl]carbamate …

Lapatinib

Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Synonyms: … N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl …
Matched Iupac: … N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl …
Matched Description: … anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and ... Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

S-23

An androgen receptor modulator.
Experimental
Matched Synonyms: … (2S)-3-(4-Chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide …
Matched Iupac: … (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide …

Sonidegib

Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Synonyms: … N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide …
Matched Iupac: … N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

TAK-075 Free base

Investigational
Matched Synonyms: … Pyrazolo(1,5-a)pyrimidine-3-carboxamide, n-(1-ethyl-1-(4-ethylphenyl)propyl)-4,5,6,7-tetrahydro-2,7,7 …
Matched Iupac: … (5R)-N-[3-(4-ethylphenyl)pentan-3-yl]-2,7,7-trimethyl-5-phenyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine- …

(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate

Experimental
Matched Name: … (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate …
Matched Iupac: … (S)-phenyl[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)carbamoyl]methyl acetate …

4-(Aminosulfonyl)-N-[(4-Fluorophenyl)Methyl]-Benzamide

Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(4-Fluorophenyl)Methyl]-Benzamide …
Matched Iupac: … N-[(4-fluorophenyl)methyl]-4-sulfamoylbenzamide …

N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide

Experimental
Matched Name: … N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide …
Matched Iupac: … N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide …

4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide

Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide …
Matched Iupac: … N-[(2,4-difluorophenyl)methyl]-4-sulfamoylbenzamide …

5-Hydroxy-N-Propargyl-1(R)-Aminoindan

Experimental
Matched Name: … 5-Hydroxy-N-Propargyl-1(R)-Aminoindan …

N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide

Experimental
Matched Name: … N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide …
Matched Iupac: … N-(6-aminohexyl)-5-chloronaphthalene-1-sulfonamide …

ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE

Experimental
Matched Name: … ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE …
Matched Iupac: … {[(Z)-[1-(ethylsulfanyl)-2-phenylethylidene]amino]oxy}sulfonic acid …

(2R)-2-PHENYL-N-PYRIDIN-4-YLBUTANAMIDE

Experimental
Matched Name: … (2R)-2-PHENYL-N-PYRIDIN-4-YLBUTANAMIDE …
Matched Iupac: … (2R)-2-phenyl-N-(pyridin-4-yl)butanamide …

1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide

Experimental
Matched Name: … 1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-butanoyl-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide …

D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide

Experimental
Matched Name: … D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-methylphenyl)methyl]pyrrolidine-2-carboxamide …

2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide

Experimental
Matched Name: … 2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide …
Matched Iupac: … 2-(4-fluorobenzenesulfonamido)-N-oxoacetamide …

N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE

Experimental
Matched Name: … N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE …
Matched Iupac: … N-[2-(4-sulfamoylphenyl)ethyl]acetamide …

N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE

Experimental
Matched Name: … N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE …
Matched Iupac: … 3-oxo-N-[(3S)-2-oxooxolan-3-yl]dodecanamide …

4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN

Experimental
Matched Name: … 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN …

Epigallocatechin gallate

Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Investigational
Matched Synonyms: … BENZOIC ACID, 3,4,5-TRIHYDROXY-, (2R,3R)-3,4-DIHYDRO-5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-2H-1-BENZOPYRAN …
Matched Description: … Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy …

Uracil mustard

Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Approved
Matched Synonyms: … 5-N,N-bis(2-chloroethyl)aminouracil …
Matched Description: … and bone marrow damage. ... It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Fimepinostat

Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and ... NUT midline carcinoma, among others. …

Tuspetinib

Tuspetinib (HM-43239) is under investigation in clinical trial NCT03850574 (Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM43239 in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … 2-Pyrimidinamine, 5-chloro-N-(3-cyclopropyl-5-(((3R,5S)-3,5-dimethyl-1-piperazinyl)methyl)phenyl)-4-( ... 5-Chloro-N-(3-cyclopropyl-5-(((3R,5S)-3,5-dimethylpiperazine-1-yl) methyl) phenyl)-4-(6-methyl-1hindol …
Matched Iupac: … 5-chloro-N-(3-cyclopropyl-5-{[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl}phenyl)-4-(6-methyl-1H-indol- …
Matched Description: … in clinical trial NCT03850574 (Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and …
Displaying drugs 3501 - 3525 of 4257 in total