Epigallocatechin gallate

DB12116InvestigationalSmall molecule

Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.

Chemical structure of Epigallocatechin gallate
Formula / weight
C22H18O11 · 458.3717 g/mol (avg)
Also known as
(-)-Epigallocatechin 3-gallate · (-)-EPIGALLOCATECHIN GALLATE · (-)-EPIGALLOCATECHIN-3-O-GALLATE · (-)-EPIGALLOCATECHIN-3-O-GALLATE (EGCG) (CONSTITUENT OF POWDERED DECAFFEINATED GREEN TEA EXTRACT) [DSC] · 3-O-GALLOYL-(-)-EPIGALLOCATECHIN
Code names
NVP-XAA 723 · PF-EGCG 90

Resolves to

Compound
UNIIBQM438CTELCAS989-51-5ChEMBLCHEMBL297453ChEBI4806PubChem65064KEGGC09731
Clinical / RWD
RxNorm24246
Structure
InChIKeyWMBWREPUVVBILR-WIYYLYMNSA-NSMILESOC1=CC(O)=C2C[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC2=C1)C1=CC(O)=C(O)C(O)=C1
Targets
P40763STAT3P21980TGM2P08246ELANEQ14534SQLEP08253MMP2P50281MMP14P03366gag-polP49327FASN+3 more

What you can answer from here — as of January 29, 2025

11Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Drug interactionStructured to mechanism, not free text
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36Clinical trialsPhase, status and sponsor resolved per trial
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2Marketed productsAcross 1 country and 2 labellers
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11+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Epigallocatechin gallate, and which of those have an active Phase 3 trial?

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