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Displaying drugs 3851 - 3875 of 8977 in total
Setogepram
Setogepram is under investigation in clinical trial NCT03184584 (Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome).
Investigational
Matched Synonyms: … 2-(3-Pentylphenyl)acetic acid ... 3-Pentylbenzenacetic acid …
Matched Iupac: … 2-(3-pentylphenyl)acetic acid …
Matched Salts cas: … 1254472-97-3 …
Matched Iupac: … 2-(3-pentylphenyl)acetic acid …
Matched Salts cas: … 1254472-97-3 …
3-Methylglutamic acid
Experimental
Matched Synonyms: … (2S,3R)-2-azanyl-3-methyl-pentanedioic acid ... (3R)-3-methyl-L-glutamic acid …
Matched Name: … 3-Methylglutamic acid …
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanedioic acid …
Matched Name: … 3-Methylglutamic acid …
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanedioic acid …
Razupenem
Razupenem has been used in trials studying the treatment of Skin Infections.
Investigational
Matched Iupac: … -2-yl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3-({4-[(5S)-5-methyl-2,5-dihydro-1H-pyrrol-3-yl]-1,3-thiazol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sinbaglustat
Investigational
Matched Synonyms: … (2s,3r,4r,5s)-2-(hydroxymethyl)-1-pentyl-3,4,5-piperidinetriol ... (2S,3R,4R,5S)-2-(Hydroxymethyl)-1-Pentylpiperidine-3,4,5-Triol ... 3,4,5-piperidinetriol, 2-(hydroxymethyl)-1-pentyl-, (2s,3r,4r,5s)- …
Matched Iupac: … (2S,3R,4R,5S)-2-(hydroxymethyl)-1-pentylpiperidine-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S)-2-(hydroxymethyl)-1-pentylpiperidine-3,4,5-triol …
LJ-2698
Investigational
Matched Synonyms: … (2r,3r,4s)-2-(2-chloro-6-(3-chlorobenzylamino)-9h-purin-9-yl)tetrahydrothiophene-3,4-diol ... 3,4-thiophenediol, 2-(2-chloro-6-(((3-chlorophenyl)methyl)amino)-9h-purin-9-yl)tetrahydro-, (2r,3r,4s …
Matched Iupac: … (2R,3R,4S)-2-(2-chloro-6-{[(3-chlorophenyl)methyl]amino}-9H-purin-9-yl)thiolane-3,4-diol …
Matched Iupac: … (2R,3R,4S)-2-(2-chloro-6-{[(3-chlorophenyl)methyl]amino}-9H-purin-9-yl)thiolane-3,4-diol …
Murizatoclax
Investigational
Matched Iupac: … (1S,3'R,6'R,7'R,8'E,11'S,12'R)-7'-{[(9aR)-octahydro-1H-pyrido[1,2-a]pyrazin-2-yl]methyl}-6-chloro-7'- ... [14.7.2.0^{3,6}.0^{19,24}]pentacosane]-8',16',18',24'-tetraene-13',13',15'-trione ... methoxy-11',12'-dimethyl-3,4-dihydro-2H-20'-oxa-13'lambda6-thia-1',14'-diazaspiro[naphthalene-1,22'-tetracyclo …
Naringenin
Experimental
Matched Iupac: … (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
RG-7795
Investigational
Matched Iupac: … (2R,3R,5S)-2-{5-amino-2-oxo-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolan-3-yl acetate …
MK-7622
MK-7622 has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]-3H,4H-benzo[h]quinazolin-4-one …
MIV-711
Investigational
Matched Synonyms: … N-[(2S)-1-[(3aS,6R,6aR)-6-Ethynyl-3-oxohexahydro-2H-furo[3,2-b]pyrrol-4-yl]-4-methyl-1-oxopentan-2-yl ... ]-4-[5-fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride …
TAK-715
TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis).
Investigational
Matched Iupac: … N-{4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl}benzamide …
SRA-737
Investigational
Matched Iupac: … 5-{[4-({[(2R)-morpholin-2-yl]methyl}amino)-5-(trifluoromethyl)pyridin-2-yl]amino}pyrazine-2-carbonitrile …
ABT-737
An inhibitor of members of the Bcl‑2 family of apoptosis regulators.
Investigational
Matched Synonyms: … Benzamide, 4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(dimethylamino) ... -1-((phenylthio)methyl)propyl)amino)-3-nitrophenyl)sulfonyl)- …
Matched Iupac: … )butan-2-yl]amino}-3-nitrobenzenesulfonyl)benzamide ... 4-[4-({4'-chloro-[1,1'-biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl …
Matched Description: … An inhibitor of members of the Bcl‑2 family of apoptosis regulators.[A252977] …
Matched Categories: … Proto-Oncogene Proteins c-bcl-2 …
Matched Iupac: … )butan-2-yl]amino}-3-nitrobenzenesulfonyl)benzamide ... 4-[4-({4'-chloro-[1,1'-biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl …
Matched Description: … An inhibitor of members of the Bcl‑2 family of apoptosis regulators.[A252977] …
Matched Categories: … Proto-Oncogene Proteins c-bcl-2 …
F6-734
F6-734 is a bispecific monoclonal antibody with affinity for anticarcinoembryonic antigen (CEA) and anti-diethylenetriamine pentaacetic acid (DTPA) (hMN-14 × m734).[A255217,A255222]
Investigational
INZ-701
INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Investigational
TAK-754
TAK-754 is an adeno-associated virus serotype 8 vector (AAV8) expressing B domain deleted codon optimized factor VIII. Developed by Takeda, it is being investigated for the treatment of hemophilia A.
Investigational
JBI-778
Investigational
DMP-777
DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy …
(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
Experimental
Matched Name: … -yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol ... (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … -yl]cyclopentyl]prop-2-en-1-ylidene]cyclohexane-1,3-diol ... (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … -yl]cyclopentyl]prop-2-en-1-ylidene]cyclohexane-1,3-diol ... (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
(3Z,6S)-6-Chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-2-piperidinyl]ethyl}imino)-2-piperazinol
Experimental
Matched Synonyms: … (3S)-3-Chloro-4-[2-[(5-chloro-1-benzothiophen-3-yl)methylamino]ethyl]-6-[2-[(2R)-piperidin-2-yl]ethylamino …
Matched Name: … (3Z,6S)-6-Chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-2-piperidinyl] ... ethyl}imino)-2-piperazinol …
Matched Iupac: … (3Z,6S)-6-chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-piperidin-2-yl ... ]ethyl}imino)piperazin-2-ol …
Matched Name: … (3Z,6S)-6-Chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-2-piperidinyl] ... ethyl}imino)-2-piperazinol …
Matched Iupac: … (3Z,6S)-6-chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-piperidin-2-yl ... ]ethyl}imino)piperazin-2-ol …
CTA018
CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent activator of vitamin D...
Investigational
AER001
AER001, an IL4/13 receptor antagonist for severe asthma and eczema currently in Phase 2 studies.
Investigational
Matched Description: … AER001, an IL4/13 receptor antagonist for severe asthma and eczema currently in Phase 2 studies. …
trans NV-04
trans NV-04 is a cardiovascular drug which shows a significant reduction in blood pressure and arterial stiffness.
Investigational
Displaying drugs 3851 - 3875 of 8977 in total