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Displaying drugs 3876 - 3900 of 8657 in total

Navocaftor

Navocaftor is under investigation in clinical trial NCT04853368 (Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/navocaftor/abbv-119 or Galicaftor/navocaftor/abbv-576 Combination Therapies in Adult Participants With Cystic Fibrosis).
Investigational
Matched Synonyms: … (5-(3-amino-5-((4-(trifluoromethoxy)phenyl)sulfonyl)pyridin-2-yl)-1,3,4-oxadiazol-2-yl)methanol ... 1,3,4-oxadiazole-2-methanol, 5-(3-amino-5-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-pyridinyl)- …

Batoprotafib

Batoprotafib is under investigation in clinical trial NCT04330664 (Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)).
Investigational
Matched Synonyms: … (3s,4s)-8-(6-amino-5-((2-amino-3-chloropyridin-4-yl)sulfanyl)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro( …
Matched Description: … in clinical trial NCT04330664 (Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2) …

(5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE

Experimental

1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea

Experimental
Matched Name: … 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino ... ]ethyl]-1,3-thiazol-2-yl]urea …
Matched Iupac: … 3-[5-methyl-2-(trifluoromethyl)furan-3-yl]-1-{5-[2-({6-[(1H-1,2,4-triazol-5-yl)amino]pyrimidin-4-yl}amino ... )ethyl]-1,3-thiazol-2-yl}urea …

N,N-dimethyl-N-(2-(((2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-((acetyloxy)methyl)oxan-2-yl)oxy)ethyl)cyclopropylammonium

Investigational
Matched Name: … N,N-dimethyl-N-(2-(((2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-((acetyloxy)methyl)oxan-2-yl)oxy)ethyl)cyclopropylammonium …
Matched Iupac: … N,N-dimethyl-N-(2-{[(2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-[(acetyloxy)methyl]oxan-2-yl]oxy}ethyl)cyclopropanaminium …

Furazolidone

A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Experimental
Vet approved
Matched Synonyms: … N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone ... 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine ... 3-(5'-Nitrofurfuralamino)-2-oxazolidone …
Matched Iupac: … 3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one …

Carpropamide

Experimental
Matched Synonyms: … (1S,3R)-2,2-dichloro-N-[(1R)-1-(4-chlorophenyl)ethyl]-1-ethyl-3-methylcyclopropanecarboxamide …
Matched Iupac: … (1S,3R)-2,2-dichloro-N-[(1R)-1-(4-chlorophenyl)ethyl]-1-ethyl-3-methylcyclopropane-1-carboximidic acid …

Dihydrouridine

Investigational
Matched Synonyms: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …

(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)]

Experimental
Matched Name: … (1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl …
Matched Iupac: … {[(1R,2S,3R,5S,6R)-2,3,5-trihydroxy-4-{[hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-6-(phosphonooxy …

4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID

Experimental
Matched Name: … 4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID …
Matched Iupac: … (3Z)-4-(2-methoxyphenyl)-2-oxobut-3-enoic acid …

AB-22

Investigational
Matched Synonyms: … (3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)- ... N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1h-pyrazolo(3,4-b)pyridin ... N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin …
Matched Iupac: … 1-(2-chloro-6-propoxypyridin-4-yl)-3-{[1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl](2 …

Bevantolol

Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Experimental
Matched Synonyms: … 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol ... 1-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-ol ... 1-(3,4-dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol …
Matched Iupac: … 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol …

N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine

Experimental
Matched Name: … N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine …
Matched Iupac: … N1-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine …

[(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron

Experimental
Matched Name: … [(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-2-(4-chlorophenyl)-1-acetamidoethyl]dihydroxyboranuide …

2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

Experimental
Matched Name: … 2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE …
Matched Iupac: … 2-cyclopropaneamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …

PD-98059

PD-98059 is an inhibitor of MAP-kinase kinase activation.
Investigational
Matched Synonyms: … 2-(2-amino-3-methoxyphenyl)-4h-1-benzopyran-4-one ... 2-(2'-amino-3'-methoxyphenyl)oxanaphthalen-4-one ... 4h-1-benzopyran-4-one, 2-(2-amino-3-methoxyphenyl)- …
Matched Iupac: … 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

S-23

An androgen receptor modulator.
Experimental
Matched Synonyms: … (2S)-3-(4-Chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide …
Matched Iupac: … (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE

Experimental
Matched Name: … 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE …
Matched Iupac: … 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …

3,4-Dihydro-2h-Pyrrolium-5-Carboxylate

Experimental

Onternabez

Investigational
Matched Synonyms: … [(1S,2S,5S)-2-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol …
Matched Iupac: … [(1S,4S,5S)-4-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methanol …

H3B-6527

H3B-6527 is under investigation in clinical trial NCT03424577 (A Study to Evaluate the Food-Effect of H3B-6527).
Investigational
Matched Synonyms: … -1-yl)phenyl}prop-2-enamide) ... -1-YL)PHENYL)PROP-2-ENAMIDE ... 2-PROPENAMIDE, N-(2-((6-((((2,6-DICHLORO-3,5-DIMETHOXYPHENYL)AMINO)CARBONYL)METHYLAMINO)-4-PYRIMIDINYL …
Matched Iupac: … -1-yl)phenyl}prop-2-enamide ... N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin …

Didesmethylrocaglamide

Didesmethylrocaglamide is a naturally-occurring derivative of rocaglamide and belongs to a class of anti-cancer phytochemicals referred to as "rocaglamides" derived from plants of the genus Aglaia. While traditionally used for their insecticidal benefits, this class of compounds is now being studied for use as chemotherapeutic agents in the treatment of...
Experimental
Matched Iupac: … (2S,3R,4R,5S,6R)-2,3-dihydroxy-10,12-dimethoxy-6-(4-methoxyphenyl)-5-phenyl-7-oxatricyclo[6.4.0.0^{2,6 …

INCB-057643

INCB-057643 is under investigation in clinical trial NCT02959437 (Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)).
Investigational
Matched Iupac: … 6-methanesulfonyl-2,2,4-trimethyl-8-{6-methyl-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-4-yl}-3,4-dihydro- ... 2H-1,4-benzoxazin-3-one …

Piceatannol

Experimental
Matched Synonyms: … 3-hydroxyresveratol ... 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol …
Matched Iupac: … 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol …

AVR-48

Investigational
Matched Synonyms: … N-((2s,3r,4r,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)tetrahydro-2h-pyran-3-yl) acetamide ... N-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)tetrahydro-2H-pyran-3-yl)acetamide ... -d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy- …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)oxan-3-yl]acetamide …
Displaying drugs 3876 - 3900 of 8657 in total