Displaying drugs 3876 - 3900 of 5753 in total
Teropavimab
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Lecanemab
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy …
Matched Description: … recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amyloid Beta-directed Antibodies ... Proteins ... Blood Proteins …
Matched Description: … recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amyloid Beta-directed Antibodies ... Proteins ... Blood Proteins …
2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole …
Matched Iupac: … (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(6-methyl-1H-1,3-benzodiazol-2-yl)oxane-3,4,5-triol …
Matched Iupac: … (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(6-methyl-1H-1,3-benzodiazol-2-yl)oxane-3,4,5-triol …
2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(5-methyl-1,3-benzothiazol-2-yl)oxane-3,4,5-triol …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(5-methyl-1,3-benzothiazol-2-yl)oxane-3,4,5-triol …
9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine
Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
AF-710B
Investigational
Matched Synonyms: … 1-(2,8-dimethyl-1-thia-3,8-diazaspiro(4.5)dec-3-yl)-3-(1h-indol-3-yl)propan-1-one ... 1-(2,8-Dimethyl-1-Thia-3,8-Diazaspiro[4.5]Dec-3-yl)-3-(1H-Indol-3-yl)Propan-1-one ... 1-propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro(4.5)dec-3-yl)-3-(1h-indol-3-yl)- …
Matched Iupac: … 1-{2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl}-3-(1H-indol-3-yl)propan-1-one …
Matched Iupac: … 1-{2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl}-3-(1H-indol-3-yl)propan-1-one …
Butylscopolamine
Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. It is not a pain medication in the normal sense, since it...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,4S,5S,7R)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Description: … It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic ... the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and …
Matched Mixtures name: … BUSCOPAN PLUS FILM TABLET, 30 ADET ... MOLIT PLUS 500 MG / 10 MG TABLET, 30 ADET ... HIOSCINAN-BUTIL BROMURO 10 MG + ACETAMINOFEN 325 MG …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... butylscopolamine and analgesics …
Matched Products: … MOLIT 20 MG/ ML ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 3 AMPUL ... BUSCODYN 20MG/ML IM/IV/SC ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,3 AMPUL …
Matched Description: … It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic ... the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and …
Matched Mixtures name: … BUSCOPAN PLUS FILM TABLET, 30 ADET ... MOLIT PLUS 500 MG / 10 MG TABLET, 30 ADET ... HIOSCINAN-BUTIL BROMURO 10 MG + ACETAMINOFEN 325 MG …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... butylscopolamine and analgesics …
Matched Products: … MOLIT 20 MG/ ML ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 3 AMPUL ... BUSCODYN 20MG/ML IM/IV/SC ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,3 AMPUL …
Soquelitinib
Investigational
Matched Synonyms: … Cyclopropanecarboxamide, N-[5-[[5-[[(3R)-hexahydro-3-methyl-4-(1-oxo-2-propen-1-yl)-1H-1,4-diazepin-1 ... N-{5-[(5-{[(3R)-4-(prop-2-enoyl)-3-methyl-1,4-diazepan-1-yl]carbonyl}-4-methoxy-2-methylphenyl)sulfanyl …
Tapentadol
Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596]
Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Salts name: … Tapentadol hydrochloride …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Salts name: … Tapentadol hydrochloride …
Camonsertib
Camonsertib is under investigation in clinical trial NCT04497116 (Study of RP-3500, Camonsertib, in Advanced Solid Tumors).
Investigational
Matched Synonyms: … 1R,3r,5S)-3-{6-[(3R)-3-methylmorpholin-4-yl]-1-(1Hpyrazol-3-yl)-1H-pyrazolo[3,4-b]pyridin-4-yl}-8-oxabicyclo ... 8-Oxabicyclo[3.2.1]octan-3-ol, 3-[6-[(3R)-3-methyl-4-morpholinyl]-1-(1H-pyrazol-3-yl)-1H-pyrazolo[3,4 ... [3.2.1]octan-3-ol …
Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen
Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Name: … Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen …
Matched Description: … (A05 and B01, respectively). ... (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A and one from subfamily B ... Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine …
Matched Description: … (A05 and B01, respectively). ... (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A and one from subfamily B ... Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine …
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Synonyms: … 17-alpha-hydroxy-progesterone caproate …
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H, …
Matched Description: … It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). ... and megestrol acetate. ... Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S. …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Progesterone and Derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H, …
Matched Description: … It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). ... and megestrol acetate. ... Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S. …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Progesterone and Derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
3-isobutyl-1-methyl-7H-xanthine
Experimental
Matched Synonyms: … 3-isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione ... 1-methyl-3-isobutylxanthine ... 3-Isobutyl-1-methyxanthine …
Matched Name: … 3-isobutyl-1-methyl-7H-xanthine …
Matched Iupac: … 1-methyl-3-(2-methylpropyl)-2,3,6,9-tetrahydro-1H-purine-2,6-dione …
Matched Name: … 3-isobutyl-1-methyl-7H-xanthine …
Matched Iupac: … 1-methyl-3-(2-methylpropyl)-2,3,6,9-tetrahydro-1H-purine-2,6-dione …
Fludeoxyglucose (18F)
Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Iupac: … (2R,3S,4R,5R)-2-(¹⁸F)fluoro-3,4,5,6-tetrahydroxyhexanal …
Matched Categories: … Indicators and Reagents …
Matched Products: … STERIFDG 250 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 3 DOZ ... [18F]Fludeoxyglucose Life Radiopharma 300-3100 MBq/ml Injektionslösung …
Matched Categories: … Indicators and Reagents …
Matched Products: … STERIFDG 250 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 3 DOZ ... [18F]Fludeoxyglucose Life Radiopharma 300-3100 MBq/ml Injektionslösung …
TG100-115
An NSAID that inhibits PI-3K gamma and delta.
Investigational
Matched Synonyms: … 3-(2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol ... 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Gadolinium cation (3+)
Experimental
Matched Synonyms: … Gadolinium(3+) ... gadolinium(3+) ion …
Matched Name: … Gadolinium cation (3+) …
Matched Iupac: … gadolinium(3+) ion …
Matched Name: … Gadolinium cation (3+) …
Matched Iupac: … gadolinium(3+) ion …
AUTO3
AUTO3 is bicistronic chimeric antigen receptor T-cell therapy investigated for acute lymphoblastic leukemia (ALL). It is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22.
Investigational
Matched Synonyms: … AUTO 3 …
Matched Description: … It is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22. …
Matched Description: … It is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22. …
Escitalopram
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Iupac: … (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Products: … ESCITALOPRAM BETA 5MG ... ESCITALOPRAM BETA 10MG ... ESCITALOPRAM BETA 15MG …
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Products: … ESCITALOPRAM BETA 5MG ... ESCITALOPRAM BETA 10MG ... ESCITALOPRAM BETA 15MG …
4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID
Experimental
Matched Name: … 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID …
Matched Iupac: … 4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid …
Matched Iupac: … 4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid …
Efavirenz
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … -benzoxazin-2-one4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one ... Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1 …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with …
Matched Mixtures name: … FORSTAVIR-LE ( Efavirenz 600 mg, Lamivudine 300 mg and Tenofovir Disoproxil Fumarate 300 mg ) Film-coated ... EFAVIRENZ 600 MG, EMTRICITABINE 200 MG AND TENOFOVIR DISOPROXIL FUMARATE 300 MG TABLETS ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Matched Products: … SUSTIVA 600MG 3 MON PACK ... STOCRIN 600 MG FILM TABLET, 30 ADET …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with …
Matched Mixtures name: … FORSTAVIR-LE ( Efavirenz 600 mg, Lamivudine 300 mg and Tenofovir Disoproxil Fumarate 300 mg ) Film-coated ... EFAVIRENZ 600 MG, EMTRICITABINE 200 MG AND TENOFOVIR DISOPROXIL FUMARATE 300 MG TABLETS ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Matched Products: … SUSTIVA 600MG 3 MON PACK ... STOCRIN 600 MG FILM TABLET, 30 ADET …
[4-(4-Hydroxy-Benzyl)-2-(2-Hydroxy-1-Methyl-Ethyl)-5-Oxo-Imidazolidin-1-Yl]-Acetic Acid
Experimental
Matched Name: … [4-(4-Hydroxy-Benzyl)-2-(2-Hydroxy-1-Methyl-Ethyl)-5-Oxo-Imidazolidin-1-Yl]-Acetic Acid …
Matched Iupac: … -1-amino-2-hydroxyethyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid …
Matched Iupac: … -1-amino-2-hydroxyethyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid …
2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide
Experimental
Matched Name: … 2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl …
Matched Iupac: … (2R)-N'-hydroxy-N-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide …
Matched Iupac: … (2R)-N'-hydroxy-N-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide …
(S)-Aspartimide
Experimental
Matched Synonyms: … 3-aminosuccinimide …
Matched Iupac: … (3S)-3-aminopyrrolidine-2,5-dione …
Matched Iupac: … (3S)-3-aminopyrrolidine-2,5-dione …
(2S)-2-amino-6-[[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methylsulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl]amino]-6-oxohexanoic acid
Experimental
Matched Name: … ]amino]-6-oxohexanoic acid ... (2S)-2-amino-6-[[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methylsulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Matched Iupac: … ]carbamoyl}pentanoic acid ... (2S)-2-amino-5-{[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methanesulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Matched Iupac: … ]carbamoyl}pentanoic acid ... (2S)-2-amino-5-{[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methanesulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Berotralstat
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Synonyms: … (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3 ... (R)-1-(3-(aminomethyl) phenyl)-N-(5-((3- cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)- ... 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5 …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- ... 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide …
Matched Description: … [L26661] Berotralstat was approved by the European Commission on April 30, 2021 [L41965] and by Health ... therapy to prevent angioedema attacks of HAE in adults and pediatric patients 12 years and older. ... activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and …
Matched Salts cas: … 1809010-52-3 …
Matched Salts name: … Berotralstat hydrochloride …
Matched Categories: … Blood and Blood Forming Organs …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- ... 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide …
Matched Description: … [L26661] Berotralstat was approved by the European Commission on April 30, 2021 [L41965] and by Health ... therapy to prevent angioedema attacks of HAE in adults and pediatric patients 12 years and older. ... activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and …
Matched Salts cas: … 1809010-52-3 …
Matched Salts name: … Berotralstat hydrochloride …
Matched Categories: … Blood and Blood Forming Organs …
Displaying drugs 3876 - 3900 of 5753 in total