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Displaying drugs 4026 - 4050 of 9904 in total

5,7,2′-trihydroxy-6,8-dimethoxyflavone

5,7,2′-trihydroxy-6,8-dimethoxyflavone (K36) is a high-affinity, naturally occurring flavonoid derivative isolated from the medicinal herb Scutellaria baicalensis Georgi .
Experimental
Matched Synonyms: … 5,7-Dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one …
Matched Iupac: … 5,7-dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethoxy-4H-chromen-4-one …

4-Deoxy-Alpha-D-Glucose

Experimental
Matched Name: … 4-Deoxy-Alpha-D-Glucose …
Matched Iupac: … (2S,3R,4S,6S)-6-(hydroxymethyl)oxane-2,3,4-triol …

alpha-D-quinovopyranose

The pyranose form of D-quinovose with an α-configuration at the anomeric position .
Experimental
Matched Iupac: … (2S,3R,4S,5S,6R)-6-methyloxane-2,3,4,5-tetrol …

3-{2,6,8-trioxo-9-[(2S,3R,4R)-2,3,4,5-tetrahydroxypentyl]-1,2,3,6,8,9-hexahydro-7H-purin-7-Yl}propyl dihydrogen phosphate

Experimental

Mavodelpar

Investigational
Matched Synonyms: … (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop-1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate …
Matched Iupac: … 2-(4-{[(2E)-3-(4-fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy …

Trehalose

Cabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
Investigational
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …

9-(4-hydroxybutyl)-N2-phenylguanine

9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.
Experimental
Matched Name: … 9-(4-hydroxybutyl)-N2-phenylguanine …
Matched Iupac: … 9-(4-hydroxybutyl)-2-(phenylamino)-6,9-dihydro-1H-purin-6-one …
Matched Description: … These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine ... 9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. …

Isaralgagene civaparvovec

Isaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA for human alpha-galactosidase A (α-Gal A) enzyme. It is developed by Sangamo Therapeutics and investigated in Fabry Disease.
Investigational
Matched Description: … Isaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA …

Pyridoxal

The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine ... 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde ... 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde …
Matched Iupac: … 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme …

O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE

Experimental
Matched Name: … O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE …
Matched Iupac: … 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …

SAR422459

SAR422459 is a Lentiviral Vector Containing The Human Abca4 Gene that is currently being investigated to treat Stargardt disease.
Investigational

VX-702

VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …

(1S,4R,7AR)-4-BUTOXY-1-[(1R)-1-FORMYLPROPYL]-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID

Experimental
Matched Name: … (1S,4R,7AR)-4-BUTOXY-1-[(1R)-1-FORMYLPROPYL]-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID …
Matched Iupac: … (1S,4R,7aR)-4-butoxy-1-[(2R)-1-oxobutan-2-yl]-2,4,5,6,7,7a-hexahydro-1H-isoindole-3-carboxylic acid …

Pocapavir

Investigational
Matched Synonyms: … 1-((2-chloro-4-methoxyphenoxy)methyl)-4-((2,6-dichlorophenoxy)methyl)benzene ... 1-[(2-Chloro-4-methoxyphenoxy)methyl]-4-[(2,6-dichlorophenoxy) methyl]benzene …
Matched Iupac: … 2-chloro-1-({4-[(2,6-dichlorophenoxy)methyl]phenyl}methoxy)-4-methoxybenzene …

Sanfetrinem cilexetil

Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil).
Investigational
Matched Synonyms: … 5s,8as,8br)-1,2,5,6,7,8,8a,8b-octahydro-1-((r)-1-hydroxyethyl)-5-methoxy-2-oxoazeto(2,1-a)isoindole-4- …

MK-4541

MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Description: … MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …

Azafenidin

Azafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).
Investigational

Phytic acid

Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational

Afelimomab

Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Investigational
Matched Description: … Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis. …

Navitoclax

Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of...
Investigational
Matched Synonyms: … (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin ... -4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-trifluoromethanesulfonylbenzenesulfonyl)benzamide …

Sinbaglustat

Investigational

3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL

Experimental
Matched Name: … 3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL …
Matched Iupac: … (2S,3S)-3-amino-4-phenylbutan-2-ol …

Diazepinomicin

Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. Diazepinomicin is a natural product derived from a non-pathogenic micro-organism. Discovered using Thallion’s DECIPHER...
Investigational

Methyl-O3-(Alpha-D-Mannose)-Alpha-D-Mannose

Experimental
Matched Iupac: … (2R,3S,4S,5S,6R)-2-{[(2R,3R,4S,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy}-6-(hydroxymethyl …

2,6-dibromo-4-phenoxyphenol

Experimental
Matched Name: … 2,6-dibromo-4-phenoxyphenol …
Matched Iupac: … 2,6-dibromo-4-phenoxyphenol …
Displaying drugs 4026 - 4050 of 9904 in total