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Displaying drugs 4051 - 4075 of 10054 in total

2-Butyl-5,6-Dihydro-1h-Imidazo[4,5-D]Pyridazine-4,7-Dione

Experimental
Matched Name: … 2-Butyl-5,6-Dihydro-1h-Imidazo[4,5-D]Pyridazine-4,7-Dione …
Matched Iupac: … 2-butyl-1H,4H,5H,6H,7H-imidazo[4,5-d]pyridazine-4,7-dione …

Simpinicline

Investigational
Matched Synonyms: … Pyrimidine, 5-((1e)-2-(3r)-3-pyrrolidinylethenyl)- …
Matched Iupac: … 5-[(1E)-2-[(3R)-pyrrolidin-3-yl]ethenyl]pyrimidine …

JNJ-39758979

JNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).
Investigational
Matched Synonyms: … 2-PYRIMIDINAMINE, 4-((3R)-3-AMINO-1-PYRROLIDINYL)-6-(1-METHYLETHYL)- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(1s,3r,4r,6s)-1,3,4,6-Tetrapkisphosphate

Experimental

4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL

Experimental
Matched Name: … 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL …
Matched Iupac: … 4-(1,3-benzoxazol-2-yl)-2,6-dibromophenol …

4-(3-ethylthiophen-2-yl)benzene-1,2-diol

Experimental
Matched Name: … 4-(3-ethylthiophen-2-yl)benzene-1,2-diol …
Matched Iupac: … 4-(3-ethylthiophen-2-yl)benzene-1,2-diol …

SP2456

Experimental
Matched Synonyms: … -1-yl]-2-oxoethyl]acetamide ... (2R)-2-Cyclohexyl-2-(diaminomethylideneamino)-N-[2-[4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …
Matched Iupac: … -1-yl}-2-oxoethyl)acetamide ... (2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]-N-(2-{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …

LH-708

Investigational
Matched Synonyms: … 1-propanone, 3,3'-dithiobis(2-amino-1-(4-methyl-1-piperazinyl)-, (2r,2'r)- …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-3-(4-methylpiperazin-1-yl)-3-oxopropyl]disulfanyl}-1-(4-methylpiperazin ... -1-yl)propan-1-one …

Benazeprilat

Experimental
Matched Synonyms: … (3S)-3-(((1S)-1-Carboxy-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid …
Matched Iupac: … (2S)-2-{[(3S)-1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino}-4-phenylbutanoic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione

Experimental

2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione

Experimental
Matched Name: … 2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione …
Matched Iupac: … 2-{4-[4-hydroxy-3-(propan-2-yl)phenoxy]-3,5-dimethylphenyl}-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione …

N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE

Experimental
Matched Name: … N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE …
Matched Iupac: … N-{[(2S)-1-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]pyrrolidin-2-yl]methyl}benzamide …

Tideglusib

Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia...
Investigational
Withdrawn
Matched Synonyms: … 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione ... 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … (GSK-3). ... anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …

5-Nitro-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione

Experimental

4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid

Experimental
Matched Name: … 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid …
Matched Iupac: … 4-{5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acid …

5-AMINO-2-{4-[(4-AMINOPHENYL)SULFANYL]PHENYL}-1H-ISOINDOLE-1,3(2H)-DIONE

Experimental
Matched Name: … 5-AMINO-2-{4-[(4-AMINOPHENYL)SULFANYL]PHENYL}-1H-ISOINDOLE-1,3(2H)-DIONE …
Matched Iupac: … 5-amino-2-{4-[(4-aminophenyl)sulfanyl]phenyl}-2,3-dihydro-1H-isoindole-1,3-dione …

Zilebesiran

Zilebesiran is under investigation in clinical trial NCT06272487 (Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)).
Investigational
Matched Synonyms: … (2S,4R)-1-{1-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2- acetamido-2-deoxy-β-D-galactopyranosyl ... )oxy]pentanamido}propyl)amino]-3-oxopropoxy}methyl)-5,11,18-trioxo-14-oxa-6,10,17- triazanonacosan-29 …
Matched Description: … and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) …

Glycerol Tribenzoate

Investigational

Dibromothymoquinone

At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]
Experimental
Matched Synonyms: … 2,5-dibromo-3-methyl-6-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione ... 2,5-dibromo-3-methyl-6-(1-methylethyl)cyclohexa-2,5-diene-1,4-dione ... 2,5-dibromo-3-isopropyl-6-methylbenzoquinone …
Matched Iupac: … 2,5-dibromo-3-methyl-6-(propan-2-yl)cyclohexa-2,5-diene-1,4-dione …

1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine

Experimental
Matched Name: … 1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine …
Matched Iupac: … 1-[(2S)-4-{5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl}morpholin-2-yl]methanamine …

3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol

Experimental
Matched Name: … 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol …
Matched Iupac: … (1E)-3-[(R)-prop-2-ene-1-sulfinyl]prop-1-ene-1-thiol …

Olitigaltin

Olitigaltin has been investigated for the treatment of Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Bis-(3-deoxy-3-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-B-D-galactopyranosyl) sulfane …
Matched Iupac: … (2S,3R,4S,5R,6R)-4-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-2-{[(2S,3R,4S,5R,6R)-4-[4-(3-fluorophenyl ... )-1H-1,2,3-triazol-1-yl]-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}-6-(hydroxymethyl)oxane-3,5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dazcapistat

Investigational
Matched Synonyms: … 5-oxazolecarboxamide, n-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl- ... N-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl-5-oxazolecarboxamide ... N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide …
Matched Iupac: … 3-{[4-(2-fluorophenyl)-2-methyl-1,3-oxazol-5-yl]formamido}-2-oxo-4-phenylbutanamide …

Indoximod

Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid ... 1-methyl-D-tryptophan ... D-1-methyltryptophan …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …

6-(4-{[2-(3-iodobenzyl)-3-oxocyclohex-1-en-1-yl]amino}phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Experimental
Matched Synonyms: … (4R)-3-[4-[[2-[(3-Iodophenyl)methyl]-3-oxocyclohexen-1-yl]amino]phenyl]-4-methyl-4,5-dihydro-1H-pyridazin …
Matched Name: … 6-(4-{[2-(3-iodobenzyl)-3-oxocyclohex-1-en-1-yl]amino}phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one …
Matched Iupac: … (5R)-6-[4-({2-[(3-iodophenyl)methyl]-3-oxocyclohex-1-en-1-yl}amino)phenyl]-5-methyl-2,3,4,5-tetrahydropyridazin ... -3-one …
Displaying drugs 4051 - 4075 of 10054 in total