Displaying drugs 4176 - 4200 of 4707 in total
Dihydroergotamine
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile.
Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … 5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman ... 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6] …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 …
Matched Description: … in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing intranasal ... use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and ... Delivery technology developed by Impel Neuropharma technology has correlated with an increase of 3-fold …
Matched Salts cas: … 5989-77-5 …
Matched Categories: … Ergot Alkaloids and Derivatives ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 …
Matched Description: … in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing intranasal ... use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and ... Delivery technology developed by Impel Neuropharma technology has correlated with an increase of 3-fold …
Matched Salts cas: … 5989-77-5 …
Matched Categories: … Ergot Alkaloids and Derivatives ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium
Experimental
Matched Name: … 3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl …
Matched Iupac: … ]phenanthridin-5-ium ... 3,8-diamino-6-phenyl-5-[6-(1-{2-[(1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl}-1H-1,2,3-triazol-5-yl)hexyl …
Matched Iupac: … ]phenanthridin-5-ium ... 3,8-diamino-6-phenyl-5-[6-(1-{2-[(1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl}-1H-1,2,3-triazol-5-yl)hexyl …
1-{[(1E)-(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXY-LAMBDA^5^-PHOSPHANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLIDENE]AMINO}UNDECAN-2-ONE
Experimental
Matched Name: … 1-{[(1E)-(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXY-LAMBDA^5^-PHOSPHANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLIDENE …
Matched Iupac: … 1-[(E)-[(3-hydroxy-2-methyl-5-{[(trihydroxy-lambda5-phosphanyl)oxy]methyl}pyridin-4-yl)methylidene]amino …
Matched Iupac: … 1-[(E)-[(3-hydroxy-2-methyl-5-{[(trihydroxy-lambda5-phosphanyl)oxy]methyl}pyridin-4-yl)methylidene]amino …
N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE
Experimental
Matched Name: … N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C] …
Matched Iupac: … 5-chloro-N-[(1R,2R)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]-1H-indole …
Matched Iupac: … 5-chloro-N-[(1R,2R)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]-1H-indole …
3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene
Experimental
Matched Name: … 3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene …
Matched Iupac: … benzyl N-[(1S)-2-phenyl-1-{[(3S)-1-phenyl-5-phenylmethanesulfonylpentan-3-yl]carbamoyl}ethyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-2-phenyl-1-{[(3S)-1-phenyl-5-phenylmethanesulfonylpentan-3-yl]carbamoyl}ethyl]carbamate …
5-(3-Amino-4,4-Dihyroxy-Butylsulfanylmethyl)-Tetrahydro-Furan-2,3,4-Triol
Experimental
Matched Name: … 5-(3-Amino-4,4-Dihyroxy-Butylsulfanylmethyl)-Tetrahydro-Furan-2,3,4-Triol …
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid …
1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene
Experimental
Matched Name: … 1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene …
Matched Iupac: … 5-(azidomethyl)-N1,N3-bis(3-{[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl …
Matched Iupac: … 5-(azidomethyl)-N1,N3-bis(3-{[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl …
1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID
Experimental
Matched Name: … 1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID …
Matched Iupac: … (1S,3R,4R,5S)-1,3,4-trihydroxy-5-(3-phenoxypropyl)cyclohexane-1-carboxylic acid …
Matched Iupac: … (1S,3R,4R,5S)-1,3,4-trihydroxy-5-(3-phenoxypropyl)cyclohexane-1-carboxylic acid …
[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
Experimental
Matched Name: … [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE …
Matched Iupac: … 2-[5-hydroxy-2-(4-hydroxyphenyl)-1-benzofuran-7-yl]acetonitrile …
Matched Iupac: … 2-[5-hydroxy-2-(4-hydroxyphenyl)-1-benzofuran-7-yl]acetonitrile …
2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
Experimental
Matched Name: … 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL …
Matched Iupac: … 2-(5-hydroxynaphthalen-1-yl)-1,3-benzoxazol-6-ol …
Matched Iupac: … 2-(5-hydroxynaphthalen-1-yl)-1,3-benzoxazol-6-ol …
(3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE
Experimental
Matched Name: … (3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide …
Matched Iupac: … (3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide …
1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE
Experimental
Matched Name: … 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE …
Matched Iupac: … (2S)-1-(2-amino-4-chloro-5-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-(2-amino-4-chloro-5-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
Experimental
Matched Name: … 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE …
Matched Iupac: … 4-[(5-benzenesulfonamido-1-methyl-1H-1,3-benzodiazol-2-yl)methyl]benzene-1-carboximidamide …
Matched Iupac: … 4-[(5-benzenesulfonamido-1-methyl-1H-1,3-benzodiazol-2-yl)methyl]benzene-1-carboximidamide …
(4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE
Experimental
Matched Name: … (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE …
Matched Iupac: … N-{[(2S,4R)-4-[(4-chlorophenyl)methoxy]pyrrolidin-2-yl]methyl}isoquinoline-5-sulfonamide …
Matched Iupac: … N-{[(2S,4R)-4-[(4-chlorophenyl)methoxy]pyrrolidin-2-yl]methyl}isoquinoline-5-sulfonamide …
3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one
Experimental
Matched Name: … 3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one …
Matched Iupac: … 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one …
Matched Iupac: … 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one …
N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine
Experimental
Matched Name: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
5-bromo-3-(pyrrolidin-1-ylsulfonyl)-1H-indole-2-carboxamide
Experimental
Matched Name: … 5-bromo-3-(pyrrolidin-1-ylsulfonyl)-1H-indole-2-carboxamide …
Matched Iupac: … 5-bromo-3-(pyrrolidine-1-sulfonyl)-1H-indole-2-carboxamide …
Matched Iupac: … 5-bromo-3-(pyrrolidine-1-sulfonyl)-1H-indole-2-carboxamide …
5-Imino-4-(2-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine
Experimental
Matched Name: … 5-Imino-4-(2-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine …
2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol
Experimental
Matched Name: … 2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol …
Matched Iupac: … 2-(methylsulfanyl)-5-[(thiophen-2-yl)methyl]-1H-imidazol-4-ol …
Matched Iupac: … 2-(methylsulfanyl)-5-[(thiophen-2-yl)methyl]-1H-imidazol-4-ol …
Velmupressin
Investigational
Matched Synonyms: … thienyl)-l-alanyl-l-valyl-l-asparaginyl-l-cysteinyl-n-(4-((aminoiminomethyl)amino)butyl)-, cyclic (1->5) …
4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
Experimental
Matched Name: … Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid …
Matched Iupac: … naphthalen-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl}methyl)phosphonic acid …
Matched Iupac: … naphthalen-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl}methyl)phosphonic acid …
Tilpisertib
Investigational
Matched Synonyms: … quinolinecarbonitrile, 6-(((s)-(1-bicyclo(1.1.1)pent-1-yl-1h-1,2,3-triazol-4-yl)(1,2-dihydro-2-methyl-1-oxo-5- …
(2S)-2-amino-6-[[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methylsulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl]amino]-6-oxohexanoic acid
Experimental
Matched Name: … )-1-[(1S)-1-carboxy-2-[(S)-methylsulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl]amino]-6-oxohexanoic acid …
Matched Iupac: … ]carbamoyl}pentanoic acid ... (2S)-2-amino-5-{[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methanesulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Matched Iupac: … ]carbamoyl}pentanoic acid ... (2S)-2-amino-5-{[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methanesulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Duvoglustat
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Investigational
Matched Synonyms: … 5-amino-1,5-dideoxy-D-glucopyranose …
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … An alpha-glucosidase inhibitor with antiviral action. …
Matched Salts cas: … 73285-50-4 …
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … An alpha-glucosidase inhibitor with antiviral action. …
Matched Salts cas: … 73285-50-4 …
Cefaloridine
Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
Experimental
Withdrawn
Matched Synonyms: … (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0 …
Matched Iupac: … 1-{[(6R,7R)-2-carboxylato-7-{[1-hydroxy-2-(thiophen-2-yl)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[ …
Matched Description: … It is derived from cephalosporin C and is a zwitterion at physiological pH. …
Matched Iupac: … 1-{[(6R,7R)-2-carboxylato-7-{[1-hydroxy-2-(thiophen-2-yl)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[ …
Matched Description: … It is derived from cephalosporin C and is a zwitterion at physiological pH. …
Displaying drugs 4176 - 4200 of 4707 in total