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Displaying drugs 401 - 425 of 11963 in total
Cetalkonium
Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Salts cas: … 3529-04-2 …
Rhodotorula rubra
Rhodotorula rubra is a fungus which can provoke allergic reactions. Rhodotorula rubra is used in allergenic testing.
Approved
Butaperazine
Butaperazine was approved in 1967 , and possibly discontinued in the 1980s .
Approved
Matched Iupac: … 1-{10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazin-2-yl}butan-1-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Trilostane
Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's …
Mestranol
The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Approved
Matched Description: … The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. …
Acer rubrum pollen
Acer rubrum pollen is the pollen of the Acer rubrum plant. Acer rubrum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 2 Maple Pollen Mix ... 3 Maple Pollen Mix ... 2 Maple Pollen Mix …
Olea europaea pollen
Olea europaea pollen is the pollen of the Olea europaea plant. Olea europaea pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Western 3 Tree Pollen Mix ... Western 3 Tree Pollen Mix …
Ruxolitinib
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Iupac: … (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile …
Matched Products: … JAKAVI 5 MG (TABLETS) ... JAKAVI 5 MG TABLET, 168 TABLET ... JAKAVI 5 MG TABLET, 14 ADET …
Matched Products: … JAKAVI 5 MG (TABLETS) ... JAKAVI 5 MG TABLET, 168 TABLET ... JAKAVI 5 MG TABLET, 14 ADET …
Sulesomab
Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.
Approved
Ethambutol
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Iupac: … (2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl]amino}ethyl)amino]butan-1-ol …
Padeliporfin
Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer. It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland. Padeliporfin...
Approved
Experimental
Matched Iupac: … palladium(2+) (4S,5S,14R,15R)-10-acetyl-4-(2-carboxyethyl)-15-ethyl-2-(2-methoxy-2-oxoethyl)-5,9,14,19 ... -tetramethyl-20-[(2-sulfoethyl)carbamoyl]-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16 …
Matched Salts cas: … 698393-30-5 …
Matched Salts cas: … 698393-30-5 …
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Iupac: … (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-9-yl 4-{2-oxo-1H,2H,3H-imidazo …
Matched Salts cas: … 1374024-48-2 …
Matched Salts cas: … 1374024-48-2 …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Products: … BET-R-Prep …
Ezogabine
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate ... ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate ... N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 …
Regadenoson
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Iupac: … 1-{6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-2-yl}-N-methyl-1H-pyrazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Lexiscan(r) (regadenoson) …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Lexiscan(r) (regadenoson) …
Alternaria alternata
Alternaria alternata is a fungus which can provoke allergic reactions. Alternaria alternata extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 3 ... Mold Mix 3 ... Mold Mix 3 …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Description: … indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 ... (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma …
Rilonacept
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Relebactam
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Lumiracoxib
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B Virus B/massachusetts/2/2012 Nymc Bx-51b Antigen (Formaldehyde Inactivated) …
Matched Name: … Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Matched Name: … Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Posaconazole
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Iupac: … 4-{4-[4-(4-{[(3R,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methoxy}phenyl ... )piperazin-1-yl]phenyl}-1-[(2S,3S)-2-hydroxypentan-3-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one …
Displaying drugs 401 - 425 of 11963 in total