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Displaying drugs 426 - 450 of 648 in total
IR208
IR208 is a synthetic T-Cell receptor peptide
vaccine developed by Immune Response Corporation.
It contains three peptides (BV5S2, BV6S5
and BV13S1) expressed by T-Cells in over 90% of MS
patients. IR208 is currently undergoing Phase II
studies in a 200-patient trial.
Investigational
Matched Description: … It contains three peptides (BV5S2, BV6S5
and BV13S1) expressed by T-Cells in over 90% of MS
patients …
4SC-203
4SC-203 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
EU204
EU204 (EBViNT) is an Epstein-Barr virus (EBV)-positive T-cell therapy currently undergoing phase 1 and 2a clinical trials in Korea for patients with EBV-positive lymphoma and solid cancer.
Investigational
Matched Description: … 2a clinical trials in Korea for patients with EBV-positive lymphoma and solid cancer. ... EU204 (EBViNT) is an Epstein-Barr virus (EBV)-positive T-cell therapy currently undergoing phase 1 and …
NTLA-2002
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …
NTLA-2001
NTLA-2001 is a clustered regularly interspaced short palindromic repeats CRISPR/ Cas9-based gene therapy consisting of a single guide RNA targeting the human TTR gene and a messenger RNA encoding Cas9.
Investigational
Matched Description: … repeats CRISPR/ Cas9-based gene therapy consisting of a single guide RNA targeting the human TTR gene and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
LX201
LX201 is a silicone matrix ocular implant that provides sustained release of cyclosporine A (CsA) locally to the eye over the course of one year. LX201 is implanted subconjunctivally (beneath the transparent membrane covering the white of the eye) in a minimally invasive procedure. The implant is being developed clinically...
Investigational
4SC-202
4SC-202 has been used in trials studying the treatment of Advanced Hematologic Malignancies.
Investigational
BT200
BT200 (Rondoraptivon pegol) is a PEGylated anti-von Willebrand factor (VWF) aptamer targeted against the VWF A1 domain. It is under investigation for the treatment of von Willebrand disease and hemophilia A.
Investigational
Matched Description: … [A261491] It is under investigation for the treatment of von Willebrand disease and hemophilia A. …
PRGN-2012
PRGN-2012 is an adenoviral vector expressing human papillomavirus (HPV) 6 and HPV 11 antigens
Investigational
Matched Description: … PRGN-2012 is an adenoviral vector expressing human papillomavirus (HPV) 6 and HPV 11 antigens …
Aldosterone
A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Experimental
Investigational
Matched Description: … renal retention of sodium and the excretion of potassium. ... A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
CAM-GM201
Investigational
Matched Synonyms: … rAAV2/1 Hex alpha and beta ... Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta …
ALT-2074
An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, primarily because of its ability to mimic the function of glutathione peroxidase.
Investigational
GTI 2040
GTI-2040 is a substance that is being studied as a treatment for cancer. It belongs to the family of drugs called antisense oligonucleotides.
Investigational
GTI-2040
GTI-2040 is under investigation in clinical trial NCT00084643 (GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors).
Investigational
Matched Description: … GTI-2040 is under investigation in clinical trial NCT00084643 (GTI-2040, Oxaliplatin, and Capecitabine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
TNP-2092
TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).
Investigational
Matched Description: … TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and …
APR-2020
APR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein
Investigational
VTP-201227
VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment of psoriasis with potential extensions into other dermatological indications. It is being developed by Vitae Pharmaceuticals.
Investigational
Matched Description: … VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment …
AGN-201904
Agn 201904 has been used in trials studying the prevention of Peptic Ulcer.
Investigational
RP-L201
Investigational
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Description: … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, …
LY-2090314
Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Investigational
Matched Description: … Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic …
Displaying drugs 426 - 450 of 648 in total