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Displaying drugs 4476 - 4500 of 9475 in total

2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide

Experimental
Matched Name: … 2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluorobenzamide …

Cinolazepam

Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
Experimental
Matched Synonyms: … 1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one ... 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile ... 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propionitrile …
Matched Iupac: … 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]propanenitrile …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

3,20-Pregnanedione

Experimental

Ochromycinone

Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).
Investigational
Matched Synonyms: … Benz(a)anthracene-1,7,12(2h)-trione, 3,4-dihydro-8-hydroxy-3-methyl-, (s)- ... (3s)-3.beta.-methyl-8-hydroxy-1,2,3,4,7,12-hexahydrobenzo(a)anthracene-1,7,12-trione …
Matched Iupac: … (3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione …

LY-294002

Specific inhibitor of phosphatidylinositol 3-kinase.
Experimental
Matched Synonyms: … 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one …
Matched Iupac: … 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one …
Matched Description: … Specific inhibitor of phosphatidylinositol 3-kinase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …

SB-269970

SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]
Investigational
Matched Iupac: … 3-{[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonyl}phenol …

Inositol-(1,3,4,5,6)-Pentakisphosphate

Experimental
Matched Iupac: … {[(1S,2R,3S,4R,5S,6R)-2-hydroxy-3,4,5,6-tetrakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …

Scriptaid

Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.
Investigational
Matched Synonyms: … 1h-benz(de)isoquinoline-2(3h)-hexanamide, n-hydroxy-1,3-dioxo- ... N-hydroxy-1,3-dioxo-1h-benz(de)isoquinoline-2(3h)-hexan amide …
Matched Iupac: … 6-{2,4-dioxo-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(12),5,7,9(13),10-pentaen-3-yl}-N-hydroxyhexanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE

Experimental
Matched Name: … 5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H ... -1,2,4-TRIAZOLE-3-SULFONAMIDE …
Matched Iupac: … 5-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]- ... 1H-1,2,4-triazole-3-sulfonamide …

Tecadenoson

Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. It is being developed by CV Therapeutics, Inc.
Investigational
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(3R)-oxolan-3-yl]amino}-9H-purin-9-yl)oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Rabacfosadine

Rabacfosadine has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin's Lymphoma, and Chronic Lymphocytic Leukemia.
Investigational
Matched Iupac: … ethyl (2S)-2-{[({2-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]ethoxy}methyl)({[(2S)-1-ethoxy-1-oxopropan ... -2-yl]amino})phosphoryl]amino}propanoate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

L-2-amino-3-butynoic acid

Experimental
Matched Synonyms: … (2S)-2-Amino-3-butynoic acid …
Matched Name: … L-2-amino-3-butynoic acid …
Matched Iupac: … (2S)-2-aminobut-3-ynoic acid …

BG-P400-TAT

Investigational
Matched Synonyms: … [4-(4-{1-[2-(2-{2-[2-(2-{2-[2-(4-guanidinomethyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy ... 2-[4-[4-[[1-[2-[2-[2-[2-[2-[2-[2-[4-[(Diaminomethylideneamino)methyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy …
Matched Iupac: … 2-(4-{4-[(1-{20-[4-(carbamimidamidomethyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol …

AVL-3288

Investigational
Matched Synonyms: … (z)-3-(4-chloroanilino)-n-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide …
Matched Iupac: … (2Z)-N-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide …

Pantothenoylaminoethenethiol

Experimental
Matched Synonyms: … 2,4-Dihydroxy-N-[2-(2-mercapto-vinylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide …
Matched Iupac: … (2R)-2,4-dihydroxy-3,3-dimethyl-N-(2-{[(1Z)-2-sulfanylethenyl]carbamoyl}ethyl)butanamide …

2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine

Experimental
Matched Synonyms: … N-1,2,3,4-Tetrahydronaphth-1-yl-2'-[3,5-dimethoxybenzamido]-2'-deoxy-adenosine …
Matched Name: … 2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine …
Matched Iupac: … N-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-(6-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-9H-purin ... -9-yl)oxolan-3-yl]-3,5-dimethoxybenzamide …

COTI-2

Investigational
Matched Synonyms: … 1-piperazinecarbothioic acid, 4-(2-pyridinyl)-, 2-(6,7-dihydro-8(5h)-quinolinylidene)hydrazide …
Matched Name: … COTI-2 …
Matched Iupac: … 4-(pyridin-2-yl)-N-{[(8E)-5,6,7,8-tetrahydroquinolin-8-ylidene]amino}piperazine-1-carbothioamide …

LM-609

LM-609 (Vitaxin) is an artificial antibody that targets a protein on the surface of newly forming blood vessels, as well as on certain tumors. In addition to cancer, the protein has been implicated in bone destruction in rheumatoid arthritis and the inflammatory process in psoriasis.
Investigational

RI 624

RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain. RI 624 is being developed by Rinat and is currently in Phase I clinical trials.
Investigational

N-6022

N6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis.
Investigational
Matched Iupac: … 3-[1-(4-carbamoyl-2-methylphenyl)-5-[4-(1H-imidazol-1-yl)phenyl]-1H-pyrrol-2-yl]propanoic acid …

(2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid

Experimental
Matched Name: … (2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene …
Matched Iupac: … (2R)-2-[(1R)-1-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene …

D-pantetheine 4'-phosphate

Experimental
Matched Synonyms: … (2R)-2-Hydroxy-N-(3-((2-mercaptoethyl)amino)-3-oxopropyl)-3,3-dimethyl-4-(phosphonooxy)butanamide …
Matched Iupac: … [(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphonic acid …

2,3-Dimercapto-1-propanesulfonic acid

Experimental

Soquelitinib

Investigational
Matched Synonyms: … N-{5-[(5-{[(3R)-4-(prop-2-enoyl)-3-methyl-1,4-diazepan-1-yl]carbonyl}-4-methoxy-2-methylphenyl)sulfanyl ... Cyclopropanecarboxamide, N-[5-[[5-[[(3R)-hexahydro-3-methyl-4-(1-oxo-2-propen-1-yl)-1H-1,4-diazepin-1 ... -yl]carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]- …

1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one

Experimental
Matched Name: … 1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one …
Matched Iupac: … 1-{3-oxo-3-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propyl}-3-phenyl-1,2-dihydroquinoxalin-2-one …
Displaying drugs 4476 - 4500 of 9475 in total