Displaying drugs 4651 - 4675 of 5429 in total
Apremilast
Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Synonyms: … N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4- …
Matched Iupac: … N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl …
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and central ... [L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated …
Matched Mixtures name: … OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OTEZLA (30 MG) ... OTEZLA TABLET 30 MG ... OPRELAST 30 MG FİLM KAPLI TABLET …
Matched Iupac: … N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl …
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and central ... [L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated …
Matched Mixtures name: … OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OTEZLA (30 MG) ... OTEZLA TABLET 30 MG ... OPRELAST 30 MG FİLM KAPLI TABLET …
Alectinib
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting ... Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed …
Matched Salts name: … Alectinib hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting ... Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed …
Matched Salts name: … Alectinib hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 3-Ring …
Triciribine phosphate
Investigational
Matched Synonyms: … 3-AMINO-1,5-DIHYDRO-5-METHYL-1-.BETA. …
Matched Iupac: … pentaen-2-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … pentaen-2-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Befiradol
Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia).
Investigational
Matched Synonyms: … (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone …
Matched Description: … Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and …
Matched Description: … Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and …
PF-04447943
PF-04447943 has been investigated for the treatment of Alzheimer's Disease.
Investigational
Matched Synonyms: … 4H-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-6-((3S,4S)-4-methyl-1-(2-pyrimidinylmethyl)-3-pyrrolidinyl ... -4H-pyrazolo(3,4-d)pyrimidin-4-one ... 6-((3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-1-(oxan-4-yl)-1H,4H,5H-pyrazolo[3,4-d] …
Matched Description: … PF-04447943 has been investigated for the treatment of Alzheimer's Disease. …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-1-(oxan-4-yl)-1H,4H,5H-pyrazolo[3,4-d] …
Matched Description: … PF-04447943 has been investigated for the treatment of Alzheimer's Disease. …
(3S)-3-(dioxidosulfanyl)-N-[(1Z)-3-oxoprop-1-en-1-yl]-4-(1H-1,2,3-triazol-1-yl)-D-valine
Experimental
Matched Name: … (3S)-3-(dioxidosulfanyl)-N-[(1Z)-3-oxoprop-1-en-1-yl]-4-(1H-1,2,3-triazol-1-yl)-D-valine …
Matched Iupac: … (1S)-1-carboxy-2-methyl-1-{[(1Z)-3-oxoprop-1-en-1-yl]amino}-3-(1H-1,2,3-triazol-1-yl)propane-2-sulfinate …
Matched Iupac: … (1S)-1-carboxy-2-methyl-1-{[(1Z)-3-oxoprop-1-en-1-yl]amino}-3-(1H-1,2,3-triazol-1-yl)propane-2-sulfinate …
(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE
Experimental
Matched Name: … (1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE …
Matched Iupac: … (1S,5S,7R)-N7-({[1,1'-biphenyl]-4-yl}methyl)-N3-hydroxy-6,8-dioxa-3-azabicyclo[3.2.1]octane-3,7-dicarboxamide …
Matched Iupac: … (1S,5S,7R)-N7-({[1,1'-biphenyl]-4-yl}methyl)-N3-hydroxy-6,8-dioxa-3-azabicyclo[3.2.1]octane-3,7-dicarboxamide …
5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
Experimental
Matched Name: … 5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …
Matched Iupac: … 5-[(3R)-3-{5-methoxy-2',6'-dimethyl-[1,1'-biphenyl]-3-yl}but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …
Matched Iupac: … 5-[(3R)-3-{5-methoxy-2',6'-dimethyl-[1,1'-biphenyl]-3-yl}but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …
(2S)-1-(Dimethylamino)-3-(4-{[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinyl]amino}phenoxy)-2-propanol
Experimental
Matched Name: … (2S)-1-(Dimethylamino)-3-(4-{[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinyl]amino}phenoxy)-2-propanol …
Matched Iupac: … (2S)-1-(dimethylamino)-3-{4-[(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]phenoxy}propan …
Matched Iupac: … (2S)-1-(dimethylamino)-3-{4-[(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]phenoxy}propan …
3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone
Experimental
Matched Name: … 3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone …
Matched Iupac: … 4-{4-[(2-oxo-2,3-dihydro-1H-indol-3-yl)methyl]phenyl}piperazine-1-carbaldehyde …
Matched Iupac: … 4-{4-[(2-oxo-2,3-dihydro-1H-indol-3-yl)methyl]phenyl}piperazine-1-carbaldehyde …
N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate
Experimental
Matched Name: … N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate …
Matched Iupac: … dodecyldimethyl(3-sulfopropyl)azanium …
Matched Iupac: … dodecyldimethyl(3-sulfopropyl)azanium …
N-[2-(1-maleimidyl)ethyl]-7-diethylaminocoumarin-3-carboxamide
Experimental
Matched Name: … N-[2-(1-maleimidyl)ethyl]-7-diethylaminocoumarin-3-carboxamide …
Matched Iupac: … 7-(diethylamino)-N-[(1Z)-2-(2,5-dioxopyrrolidin-1-yl)ethenyl]-2-oxo-2H-chromene-3-carboxamide …
Matched Iupac: … 7-(diethylamino)-N-[(1Z)-2-(2,5-dioxopyrrolidin-1-yl)ethenyl]-2-oxo-2H-chromene-3-carboxamide …
3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol
Experimental
Matched Name: … 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol …
Matched Iupac: … (1E)-3-[(R)-prop-2-ene-1-sulfinyl]prop-1-ene-1-thiol …
Matched Iupac: … (1E)-3-[(R)-prop-2-ene-1-sulfinyl]prop-1-ene-1-thiol …
5-(1-Carboxy-1-Phosphonooxy-Ethoxyl)-Shikimate-3-Phosphate
Experimental
Matched Name: … 5-(1-Carboxy-1-Phosphonooxy-Ethoxyl)-Shikimate-3-Phosphate …
Matched Iupac: … acid ... (3R,4S,5R)-5-[(1S)-1-carboxy-1-(phosphonooxy)ethoxy]-4-hydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic …
Matched Iupac: … acid ... (3R,4S,5R)-5-[(1S)-1-carboxy-1-(phosphonooxy)ethoxy]-4-hydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic …
1-O-Octyl-2-Heptylphosphonyl-Sn-Glycero-3-Phosphoethanolamine
Experimental
Matched Name: … 1-O-Octyl-2-Heptylphosphonyl-Sn-Glycero-3-Phosphoethanolamine …
Matched Iupac: … (2-aminoethoxy)[(2R)-2-{[heptyl(hydroxy)phosphoryl]oxy}-3-(octyloxy)propoxy]phosphinic acid …
Matched Iupac: … (2-aminoethoxy)[(2R)-2-{[heptyl(hydroxy)phosphoryl]oxy}-3-(octyloxy)propoxy]phosphinic acid …
3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide
Experimental
Matched Name: … 3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide …
Matched Iupac: … 3-nitro-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide …
Matched Iupac: … 3-nitro-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide …
(5-BROMO-4-CHLORO-3-INDOLYL)-A-D-MANNOSE
Experimental
Matched Name: … (5-BROMO-4-CHLORO-3-INDOLYL)-A-D-MANNOSE …
Matched Iupac: … (2R,3S,4S,5S,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Iupac: … (2R,3S,4S,5S,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol …
N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE
Experimental
Matched Name: … N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE …
Matched Iupac: … 3-[3-(carbamimidamidooxy)propoxy]-5-chloro-N-cyclopentyl-N-(prop-2-en-1-yl)benzamide …
Matched Iupac: … 3-[3-(carbamimidamidooxy)propoxy]-5-chloro-N-cyclopentyl-N-(prop-2-en-1-yl)benzamide …
1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide
Experimental
Matched Name: … 1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
(3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE
Experimental
Matched Name: … (3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide …
Matched Iupac: … (3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide …
2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
Experimental
Matched Name: … 2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE …
Matched Iupac: … 2-cyclopropaneamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …
Matched Iupac: … 2-cyclopropaneamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …
N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine
Experimental
Matched Name: … N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine …
Matched Iupac: … acid ... (2S)-3-methyl-2-{8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene-5-sulfonamido}butanoic …
Matched Iupac: … acid ... (2S)-3-methyl-2-{8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene-5-sulfonamido}butanoic …
3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
Experimental
Matched Name: … 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL …
Matched Iupac: … 3-chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol …
Matched Iupac: … 3-chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol …
3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
Experimental
Matched Name: … 3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE …
Matched Iupac: … 3-chloro-2,2-dimethyl-N-[4-(trifluoromethyl)phenyl]propanamide …
Matched Iupac: … 3-chloro-2,2-dimethyl-N-[4-(trifluoromethyl)phenyl]propanamide …
1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL
Experimental
Matched Name: … 1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL …
Matched Iupac: … {[(2S)-1-(decyloxy)-3-(2,2,2-trifluoroethoxy)propan-2-yl]oxy}(methoxy)phosphinic acid …
Matched Iupac: … {[(2S)-1-(decyloxy)-3-(2,2,2-trifluoroethoxy)propan-2-yl]oxy}(methoxy)phosphinic acid …
Displaying drugs 4651 - 4675 of 5429 in total