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Displaying drugs 451 - 475 of 677 in total
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. …
Matched Products: … Sooryehan Pure Whitening Spot Treatment …
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … Anti-VEGF monoclonal antibody ... Anti-VEGF Humanized Monoclonal Antibody
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Synonyms: … 5F11 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
Matched Synonyms: … Monoclonal antibody B43.13 …
Matched Description: … Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Experimental
Matched Synonyms: … Monoclonal antibody anti-SSEA-1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … O-sulfo-L-serine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … O2-Sulfo-Glucuronic Acid …
Cardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human health. Cardamonin's name comes from the fact that it can be found in cardamom spice.
Experimental
Matched Products: … Isaknox White Symphony Multi Laser Spot
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and bladder cancers.
Investigational
Matched Synonyms: … ANTI-PSCA MONOCLONAL ANTIBODY AGS-1C4D4 …
Matched Description: … significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and ... MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Recombinant anti-CD40 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody 5c8 …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies).
Investigational
Matched Synonyms: … Agonistic anti-OX40 monoclonal antibody MEDI6469 …
Matched Description: … and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies) ... MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety …
Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational
Matched Synonyms: … Anti-OX40 Antibody PF-04518600 …
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Synonyms: … Anti-CD20/CD3 monoclonal antibody REGN1979 …
Matched Description: … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, ... Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody
Investigational
Matched Synonyms: … antibody-drug conjugate DP303c …
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.
Investigational
Matched Synonyms: … Recombinant anti-claudin 18.2 monoclonal antibody
Matched Description: … HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2. …
2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Investigational
Matched Synonyms: … Anti-TGF-beta antibody 2G7 ... Anti-TGF-beta monoclonal antibody 2G7 ... Anti-transforming growth factor-beta monoclonal antibody 2G7 …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational
Matched Synonyms: … Anti-egfr/c-met bispecific antibody emb-01 ... Anti-egfr/anti-c-met bispecific antibody emb-01 …
Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.
Investigational
Matched Synonyms: … Anti-CD80 monoclonal antibody
Matched Description: … Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … Anti-tgf-beta monoclonal antibody nis793 …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … GENTULIZUMAB (anti-CD47 Humanized Monoclonal Antibody) …
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Synonyms: … Monoclonal antibody hMN-14 ... MN14 monoclonal antibody to carcinoembryonic antigen …
Matched Description: … Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 451 - 475 of 677 in total