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Displaying drugs 4751 - 4775 of 10226 in total
K-777
Investigational
Matched Synonyms: … 4-methylpiperazine-1-carboxylic acid [1-(3-benzenesufonyl-1-phenethylallyl-carbamoyl)-2-phenylethyl] ... 1-piperazinecarboxamide, 4-methyl-n-((1s)-2-oxo-2-(((1s)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen ... 4-methylpiperazine-1-carboxylic acid(1-((3-benzenesufonyl-1-phenethylallyl)carbamoyl)-2-phenylethyl)amide …
Matched Iupac: … (2S)-N-[(1E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-2-{[(E)-4-methylpiperazine-1-carbonyl]amino ... }-3-phenylpropanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2S)-N-[(1E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-2-{[(E)-4-methylpiperazine-1-carbonyl]amino ... }-3-phenylpropanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
3-Carbamimidamido-1,1-diphenylurea
Experimental
Matched Name: … 3-Carbamimidamido-1,1-diphenylurea …
Matched Iupac: … 3-[(diaminomethylidene)amino]-1,1-diphenylurea …
Matched Iupac: … 3-[(diaminomethylidene)amino]-1,1-diphenylurea …
N-phenyl-1H-pyrazole-3-carboxamide
Experimental
Matched Name: … N-phenyl-1H-pyrazole-3-carboxamide …
Matched Iupac: … N-phenyl-1H-pyrazole-3-carboxamide …
Matched Iupac: … N-phenyl-1H-pyrazole-3-carboxamide …
Dilmapimod
Dilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others. Dilmapimod (SB-681323) is a p38 MAP-kinase inhibitor that has potential uses in inflammatory conditions such as RA (Rheumatoid Arthritis). Previous p38 MAP-kinase inhibitors have been...
Investigational
Matched Iupac: … 8-(2,6-difluorophenyl)-2-[(1,3-dihydroxypropan-2-yl)amino]-4-(4-fluoro-2-methylphenyl)-7H,8H-pyrido[2,3 …
Matched Salts cas: … 937169-00-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 937169-00-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mibenratide
Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies).
Investigational
Matched Iupac: … )-34-(hydroxymethyl)-55-[(4-hydroxyphenyl)methyl]-10,19-dimethyl-3,6,9,12,15,18,21,24,27,30,33,36,39,42,48,51,54,57 ... 3-[(1R,4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R,40S,43S,49S,52S,55S)-40-(4-aminobutyl)-28-benzyl ... -4,7-bis(3-carbamimidamidopropyl)-22-(2-carbamoylethyl)-52-(carbamoylmethyl)-16,31,49-tris(carboxymethyl …
Aloxistatin
Investigational
Matched Synonyms: … Ethyl (+)-(2s,3s)-2,3-epoxy-n-((s)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate …
Matched Iupac: … ethyl (2S,3S)-3-{[(1S)-3-methyl-1-[(3-methylbutyl)carbamoyl]butyl]carbamoyl}oxirane-2-carboxylate …
Matched Iupac: … ethyl (2S,3S)-3-{[(1S)-3-methyl-1-[(3-methylbutyl)carbamoyl]butyl]carbamoyl}oxirane-2-carboxylate …
AV608
AV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Investigational
Matched Description: … AV608 is a NK-1 antagonist. …
MEDI-6469
MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies).
Investigational
VO659
VO659 is an antisense oligonucleotide being investigated for the treatment of Huntington's disease.
Investigational
4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine
Experimental
Matched Name: … 4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine …
Matched Iupac: … 4-{4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-2-amine …
Matched Iupac: … 4-{4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-2-amine …
4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine
Experimental
Matched Name: … 4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine …
Matched Iupac: … 4-{4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-2-amine …
Matched Iupac: … 4-{4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-2-amine …
Olvimulogene nanivacirepvec
Olvimulogene nanivacirepvec is under investigation in clinical trial NCT01443260 (A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis).
Investigational
1-Naphthyl-L-alanine
Experimental
Matched Synonyms: … (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid ... Naphthalen-2-yl-3-alanine ... L-beta-(1-Naphthyl)alanine …
Matched Name: … 1-Naphthyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid …
Matched Name: … 1-Naphthyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid …
Tavokinogene telseplasmid
Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE
Experimental
Matched Name: … (3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE …
Matched Iupac: … (1R,3R,5S)-8,8-dimethyl-3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yloxy}-8-azabicyclo …
Matched Iupac: … (1R,3R,5S)-8,8-dimethyl-3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yloxy}-8-azabicyclo …
Tideglusib
Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia...
Investigational
Withdrawn
Matched Synonyms: … 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … (GSK-3). ... anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … (GSK-3). ... anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …
PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE
Experimental
Matched Iupac: … {[(2S,3S,4R,5R)-3-amino-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxyoxolan-2-yl]methoxy}phosphonic acid …
UK-432097
UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … 6-[(2,2-diphenylethyl)amino]-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-N-[2-({[1- …
3-(cyclohexylamino)propanesulfonic acid
Experimental
Matched Synonyms: … 3-(Cyclohexylamino)-1-propanesulfonic acid ... 3-Cyclohexylaminopropane-1-sulphonic acid …
Matched Name: … 3-(cyclohexylamino)propanesulfonic acid …
Matched Iupac: … 3-(cyclohexylamino)propane-1-sulfonic acid …
Matched Name: … 3-(cyclohexylamino)propanesulfonic acid …
Matched Iupac: … 3-(cyclohexylamino)propane-1-sulfonic acid …
CLL1-CD33 compound chimeric antigen receptor T cells
Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …
4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine
Experimental
Matched Name: … 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine …
Matched Iupac: … 4-{1-[(2,6-dichlorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}pyrimidin-2-amine …
Matched Iupac: … 4-{1-[(2,6-dichlorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}pyrimidin-2-amine …
5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid
Experimental
Matched Name: … 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
(10E,12Z)-octadecadienoic acid
Experimental
Displaying drugs 4751 - 4775 of 10226 in total