Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 4926 - 4950 of 5753 in total

Entrectinib

Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. ... FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and ... This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET …

4'-Thio-fac

4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Synonyms: … 4-Amino-1-[(2R,3S,4S,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrothiophen-2-Yl] Pyrimidin-2(1H) …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and …

BR101801

Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …

Indotecan

Investigational
Matched Synonyms: … 5h-(1,3)dioxolo(4',5':5,6)indeno(1,2-c)isoquinoline-5,12(6h)-dione, 2,3-dimethoxy-6-(3-(4-morpholinyl …
Matched Salts name: … Indotecan hydrochloride …

Dazcapistat

Investigational
Matched Synonyms: … 5-oxazolecarboxamide, n-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl- ... N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide ... N-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl-5-oxazolecarboxamide …
Matched Iupac: … 3-{[4-(2-fluorophenyl)-2-methyl-1,3-oxazol-5-yl]formamido}-2-oxo-4-phenylbutanamide …

Ropsacitinib

Investigational
Matched Synonyms: … Cyclobutaneacetonitrile, 3-cyano-1-(4-(6-(1-methyl-1h-pyrazol-4- yl)pyrazolo(1,5-a)pyrazin-4-yl)-1h-pyrazol ... Trans-3-cyano-1-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrazolo(1,5-a)pyrazin-4-yl)- 1h-pyrazol-1-yl)-cyclobutaneacetonitrile …
Matched Iupac: … (1r,3r)-3-(cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl …

Selonsertib

Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
Investigational
Matched Synonyms: … 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin ... BENZAMIDE, 5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-(6-(4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL-3- ... 5-(4-Cyclopropyl-1H-imidazol-l-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide …
Matched Iupac: … 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin …
Matched Description: … Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib ... in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis). …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Protein Kinase Inhibitors …

5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine

Experimental
Matched Name: … 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine …

3-Amino-N-{4-[2-(2,6-Dimethyl-Phenoxy)-Acetylamino]-3-Hydroxy-1-Isobutyl-5-Phenyl-Pentyl}-Benzamide

Experimental
Matched Name: … 3-Amino-N-{4-[2-(2,6-Dimethyl-Phenoxy)-Acetylamino]-3-Hydroxy-1-Isobutyl-5-Phenyl-Pentyl}-Benzamide …
Matched Iupac: … N-[(2S,3S,5S)-5-[(4-aminophenyl)formamido]-3-hydroxy-7-methyl-1-phenyloctan-2-yl]-2-(2,6-dimethylphenoxy …

3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE

Experimental
Matched Name: … 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE …
Matched Iupac: … 3-fluoro-5-(morpholin-4-yl)-N-{3-[2-(pyridin-4-yl)ethyl]-1H-indol-5-yl}benzamide …

(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE

Experimental
Matched Name: … (3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE …
Matched Iupac: … (3R,4S)-1-[6-(6-methoxypyridin-3-yl)pyrimidin-4-yl]-4-(2,4,5-trifluorophenyl)pyrrolidin-3-amine …

2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[2N-METHYL-2H-TETRAZOL-5-YL]-PHENOL

Experimental
Matched Name: … 2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[2N-METHYL-2H-TETRAZOL-5-YL]-PHENOL …
Matched Iupac: … 5-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-2-methyl-2H-1,2,3,4-tetrazole …

N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide

Experimental
Matched Synonyms: … N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide ... D-Gluconamide, N,N'-((((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propanediyl ... N,N'-((((3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propandiyl)bis-D-gluconamide …
Matched Name: … N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide …
Matched Iupac: … (2R,3S,4R,5R)-N-{3-[(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro ... -1H-cyclopenta[a]phenanthren-1-yl]-N-{3-[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanamido]propyl}pentanamido …

(3s)-3-Amino-1-(Cyclopropylamino)Heptane-2,2-Diol

Experimental
Matched Name: … (3s)-3-Amino-1-(Cyclopropylamino)Heptane-2,2-Diol …
Matched Iupac: … (3S)-3-amino-1-(cyclopropylamino)heptane-2,2-diol …

N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide

Experimental
Matched Name: … N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)benzamide …

(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. [PubChem]
Experimental
Matched Name: … (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium …
Matched Iupac: … [(2R)-3-carboxy-2-hydroxypropyl]trimethylazanium …
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …

1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate

Experimental
Matched Name: … 1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate …
Matched Iupac: … [(2S)-3-(hexanoyloxy)-2-hydroxypropoxy]phosphonic acid …

5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol

Experimental
Matched Name: … 5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol …
Matched Iupac: … 5-[(1E)-3,3-dihydroxyprop-1-en-1-yl]-3-methoxybenzene-1,2-diol …

1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Experimental
Matched Name: … 1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE …
Matched Iupac: … [(2S)-3-(acetyloxy)-2-hydroxypropoxy](2-azaniumylethoxy)phosphinic acid …

N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide

Experimental
Matched Name: … N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide …
Matched Iupac: … (2S)-N-[(3-chlorophenyl)methyl]-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide …

N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide

N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.
Experimental
Matched Name: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-(3-phenylpropanoyl)pyrrolidine-2-carboxamide …
Matched Description: … These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin. ... This compound belongs to the alpha amino acid amides. ... N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. …

3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC

Experimental
Matched Name: … 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC …
Matched Iupac: … 2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid …

PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE

Experimental
Matched Name: … PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE …
Matched Iupac: … 2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole …

3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE

Experimental
Matched Name: … 3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE …
Matched Iupac: … (2Z)-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-4,6-dihydroxy-2,3-dihydro-1-benzofuran-3-one …

2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide

Experimental
Matched Name: … 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide …
Matched Iupac: … 2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide …
Displaying drugs 4926 - 4950 of 5753 in total