Displaying drugs 476 - 500 of 2456 in total
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Conestat alfa …
Matched Name: … Conestat alfa …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... conestat alfa ... Blood and Blood Forming Organs …
Matched Name: … Conestat alfa …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... conestat alfa ... Blood and Blood Forming Organs …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Susoctocog alfa …
Matched Name: … Susoctocog alfa …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... B domain replaced with a twenty-four amino acid linker. …
Matched Categories: … Blood and Blood Forming Organs ... susoctocog alfa …
Matched Name: … Susoctocog alfa …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... B domain replaced with a twenty-four amino acid linker. …
Matched Categories: … Blood and Blood Forming Organs ... susoctocog alfa …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Efmoroctocog alfa …
Matched Name: … Efmoroctocog alfa …
Matched Description: … Other drug products with similar structure and function to Efmoroctocog alfa include [DB13999], which ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. …
Matched Name: … Efmoroctocog alfa …
Matched Description: … Other drug products with similar structure and function to Efmoroctocog alfa include [DB13999], which ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. …
Beroctocog alfa
Approved
Investigational
Matched Name: … Beroctocog alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pegvorhyaluronidase alfa
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … Pegvorhyaluronidase alfa ... (36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA …
Matched Name: … Pegvorhyaluronidase alfa …
Matched Description: … Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). ... Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … Pegvorhyaluronidase alfa …
Matched Description: … Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). ... Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single …
Matched Categories: … Enzymes and Coenzymes …
Pabinafusp alfa
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Pabinafusp alfa ... HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID ... receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa …
Matched Name: … Pabinafusp alfa …
Matched Description: … Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With …
Matched Categories: … pabinafusp alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Pabinafusp alfa …
Matched Description: … Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With …
Matched Categories: … pabinafusp alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Alunacedase alfa
Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Investigational
Matched Synonyms: … Alunacedase alfa …
Matched Name: … Alunacedase alfa …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Name: … Alunacedase alfa …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Agalsidase alfa
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … Agalsidase alfa ... Agalsidase alfa (genetical recombination) …
Matched Name: … Agalsidase alfa …
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] ... [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after …
Matched Categories: … Amino Acids, Peptides, and Proteins ... agalsidase alfa ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Name: … Agalsidase alfa …
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] ... [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after …
Matched Categories: … Amino Acids, Peptides, and Proteins ... agalsidase alfa ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Onfekafusp alfa …
Matched Name: … Onfekafusp alfa …
Matched Description: … Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal …
Matched Name: … Onfekafusp alfa …
Matched Description: … Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Efineptakin alfa …
Matched Name: … Efineptakin alfa …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Efineptakin alfa …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Efmitermant alfa
Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial NCT03124459 (Study of ACE-083 in Patients With Charcot-marie-tooth Disease).
Investigational
Matched Name: … Efmitermant alfa …
Matched Description: … Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial …
Matched Description: … Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial …
Nanrilkefusp alfa
Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity binding sushi+ domain of IL-15 receptor alpha (IL-15Ra).
Investigational
Matched Name: … Nanrilkefusp alfa …
Matched Description: … Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity …
Matched Description: … Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity …
Retlirafusp alfa
Investigational
Matched Synonyms: … 136-type II transforming growth factor .beta. receptor (human isoform 1), disulfide with (85-glutamic acid …
Matched Name: … Retlirafusp alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Retlirafusp alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Clervonafusp alfa
Investigational
Matched Synonyms: … -glucosidase fragment, glycoform alfa …
Matched Name: … Clervonafusp alfa …
Matched Name: … Clervonafusp alfa …
Reveglucosidase alfa
Investigational
Matched Synonyms: … maltase, aglucosidase alfa) produced in chinese hamster ovary (cho) cells, glycoform alfa ... insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid …
Matched Name: … Reveglucosidase alfa …
Matched Name: … Reveglucosidase alfa …
Dalcinonacog alfa
Dalcinonacog alfa is a recombinant human factor IX (FIX) variant. It is being investigated for the treatment of hemophilia B.
Investigational
Matched Name: … Dalcinonacog alfa …
Matched Description: … Dalcinonacog alfa is a recombinant human factor IX (FIX) variant. …
Matched Description: … Dalcinonacog alfa is a recombinant human factor IX (FIX) variant. …
Cinrebafusp alfa
Investigational
Matched Synonyms: … ) (HUMAN-MUS MUSCULUS MONOCLONAL PRS-343 .GAMMA.4-CHAIN) FUSION PROTEIN PEPTIDE (SYNTHETIC 15-AMINO ACID …
Matched Name: … Cinrebafusp alfa …
Matched Name: … Cinrebafusp alfa …
Troplasminogen alfa
Troplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in Acute Ischaemic Stroke).
Investigational
Matched Name: … Troplasminogen alfa …
Matched Description: … Troplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Troplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Flufenamic acid
An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
Approved
Matched Synonyms: … Flufenamic acid ... acide flufénamique ... Acidum flufenamicum …
Matched Name: … Flufenamic acid …
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid …
Matched Description: … An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. ... It is used in musculoskeletal and joint disorders and administered by mouth and topically. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... flufenamic acid …
Matched Name: … Flufenamic acid …
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid …
Matched Description: … An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. ... It is used in musculoskeletal and joint disorders and administered by mouth and topically. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... flufenamic acid …
Betamethasone
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream ... AXCEL FUSIDIC ACID-B CREAM ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics ... betamethasone and antibiotics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... BETAMETHASON ACIS CRINALE …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream ... AXCEL FUSIDIC ACID-B CREAM ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics ... betamethasone and antibiotics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... BETAMETHASON ACIS CRINALE …
Interferon alfa
Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13...
Investigational
Matched Synonyms: … Interferon alfa …
Matched Name: … Interferon alfa …
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa …
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Elosulfase alfa …
Matched Name: … Elosulfase alfa …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim ... Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Matched Categories: … elosulfase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Matched Name: … Elosulfase alfa …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim ... Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Matched Categories: … elosulfase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Poractant alfa
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Name: … Poractant alfa …
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... phospholipids) and 1% hydrophobic low molecular weight proteins (surfactant associated proteins SP-B …
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... phospholipids) and 1% hydrophobic low molecular weight proteins (surfactant associated proteins SP-B …
Antithrombin Alfa
Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.
Approved
Investigational
Matched Synonyms: … Antithrombin Alfa …
Matched Name: … Antithrombin Alfa …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Name: … Antithrombin Alfa …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin alfa …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... and the placebo treatment in patient subjects, thrombin alfa is not currently approved by certain organizations …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... and the placebo treatment in patient subjects, thrombin alfa is not currently approved by certain organizations …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Displaying drugs 476 - 500 of 2456 in total