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Displaying drugs 526 - 550 of 756 in total

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … who require larger and more frequent doses. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... an improved safety profile with a lower risk of overdose and respiratory depression. …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Products: … BUPRE-HEXAL 7 T 5 UG/H ... BUPRE-HEXAL 4 T 35 UG/H ... BUPRE-HEXAL 4 T 70 UG/H …

Ropinirole

Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and …
Matched Products: … ROPINIROL HEXAL 1MG ... ROPINIROL-HEXAL 1MG ... ROPINIROL-HEXAL 2MG …

Ibandronate

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and …
Matched Categories: … ibandronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … IBANDRONSAEURE HEXAL 2MG ... IBANDRONSAEURE HEXAL 4MG ... IBANDRONSAEURE HEXAL 6MG …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Synonyms: … 2-methyl-3β-hydroxy-1αH,5αH-tropane-2β-carboxylate benzoate (ester) …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... the eye, ear, nose, and throat. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Categories: … Analgesics and Anesthetics …

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and …
Matched Categories: … morphine and antispasmodics …
Matched Products: … MORPHIN HEXAL 20MG RET ... MORPHIN HEXAL 45MG RET ... MORPHIN HEXAL 100MG RET TA …

Selegiline

A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Matched Products: … SELEGILIN HEXAL 5MG TABL ... SELEGILIN HEXAL 10MG TABL …

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior ... abuse, and can significantly impact the quality of life of patients and caregivers. ... [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to …
Matched Products: … ZIPRASIDON HEXAL 20MG ... ZIPRASIDON HEXAL 40MG ... ZIPRASIDON HEXAL 60MG …

Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and ... mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... metoprolol and felodipine ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers …
Matched Products: … FELODIPINA HEXAL ... Felodipin Hexal retard 5 mg - Filmtabletten ... Felodipin Hexal retard 10 mg - Filmtabletten …

2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate

Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate …

Sumatriptan

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … sumatriptan and naproxen ... Genito Urinary System and Sex Hormones ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN-HEXAL 50MG ... SUMATRIPTAN-HEXAL 100MG ... SUMATRIPTAN-HEXAL N 50MG …

Pravastatin

Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … PRAVASTATIN HEXAL 10MG ... PRAVASTATIN HEXAL 20MG ... PRAVASTATIN HEXAL 30MG …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Categories: … Benzamides and benzamide derivatives ... Benzoates …
Matched Products: … SULPIRID HEXAL 50MG ... SULPIRID HEXAL 100MG TABL ... SULPIRID HEXAL 200MG TABL …

Dabigatran etexilate

Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Matched Description: … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Dabigatranetexilat Hexal 75 mg - Hartkapseln ... Dabigatranetexilat Hexal 110 mg - Hartkapseln ... Dabigatranetexilat Hexal 150 mg - Hartkapseln …

Temozolomide

Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Description: … malignant brain tumours with poor prognosis and limited treatment options. ... guanine bases leading to DNA lesions and eventual apoptosis. ... Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TEMOZOLOMIDE HEXAL ... Temozolomide Hexal ... TEMOZOLOMID HEXAL 5MG …

Alfacalcidol

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … malabsorptive rickets and osteomalacia, vitamin D-dependent rickets and osteomalacia, and hypophosphataemic ... vitamin D resistant rickets and osteomalacia. ... [A234044] It plays an essential function in calcium homeostasis and bone metabolism. …
Matched Categories: … Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and alfacalcidol, sequential …
Matched Products: … ALFACALCIDOL HEXAL 1 UG ... ALFACALCIDOL HEXAL 0.5 UG ... ALFACALCIDOL HEXAL 0.25 UG …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and …
Matched Products: … PAROXETINA HEXAL ... Paroxat Hexal 10 mg - Filmtabletten ... Paroxat Hexal 20 mg - Filmtabletten …

Propiverine

Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) . Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the...
Approved
Investigational
Matched Description: … prevalence in men and women. ... OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents ... condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … PROPIVERIN HEXAL 15MG FTBL ... PROPIVERIN HEXAL 5MG FILMT …

Tamoxifen

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TAMOXIFEN 10MG HEXAL ... TAMOXIFEN 20MG HEXAL ... TAMOXIFEN 30MG HEXAL …

Delorazepam

Delorazepam is a benzodiazepine which, like other drugs in its class, possesses anxiolytic, skeletal muscle relaxant, hypnotic and anticonvulsant properties. It may have adverse effects such as drowsiness, and cognitive impairments such as short term memory impairment. Delorazepam is an active metabolite of the benzodiazepine known as cloxazolam. It is...
Experimental
Illicit
Matched International brands: … Delorazepam Hexal …
Matched Description: … benzodiazepine which, like other drugs in its class, possesses anxiolytic, skeletal muscle relaxant, hypnotic and ... It may have adverse effects such as drowsiness, and cognitive impairments such as short term memory impairment …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Products: … DELORAZEPAM HEXAL …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Products: … TOPIRAMATO HEXAL ... TOPIRAMAT-HEXAL 25MG ... TOPIRAMAT-HEXAL 100MG FILM …

Cavrotolimod

Investigational
Matched Synonyms: … -CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53 …

1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol

Experimental
Matched Name: … 1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol …

1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole

Experimental
Matched Name: … 1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole …

5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE

Experimental
Matched Name: … 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …

3-(4-carbamoyl-1-carboxy-2-methylsulfonyl-buta-1,3-dienylamino)-indolizine-2-carboxylic acid

Experimental
Matched Name: … 3-(4-carbamoyl-1-carboxy-2-methylsulfonyl-buta-1,3-dienylamino)-indolizine-2-carboxylic acid …
Displaying drugs 526 - 550 of 756 in total