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Displaying drugs 5801 - 5825 of 10413 in total
AGTC-402
AGTC-402 is a recombinant adeno-associated virus vector expressing the cyclic nucleotide gated channel alpha subunit (CNGA3).
Investigational
1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone
Experimental
Matched Name: … 1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone …
Matched Iupac: … 3-[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-4H-1lambda6,2,4-benzothiadiazine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-4H-1lambda6,2,4-benzothiadiazine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Skin-derived ABCB5-positive Mesenchymal Stem cells
Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).
Investigational
Ro 12-7310
Experimental
YK-4-279
Investigational
Matched Synonyms: … 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
ATN-161
ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. This approach targeting both the tumor vasculature and the cancer cells themselves, may be effective...
Investigational
Matched Iupac: … (2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-{[(2S)-1-acetylpyrrolidin-2-yl]formamido}-3-(1H-imidazol-5-yl)propanamido ... ]-3-hydroxypropanamido]-3-sulfanylpropanamido]butanediamide …
Matched Description: … ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. ... Since the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor …
Matched Description: … ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. ... Since the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor …
Esmirtazapine
Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. Merck has...
Investigational
Matched Synonyms: … (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine …
Matched Iupac: … (7S)-5-methyl-2,5,19-triazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors …
Matched Salts cas: … 680993-85-5 …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-2 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT3 Receptor Antagonists …
Matched Iupac: … (7S)-5-methyl-2,5,19-triazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors …
Matched Salts cas: … 680993-85-5 …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-2 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT3 Receptor Antagonists …
Oxyphenisatin
A laxative that undergoes enterohepatic circulation. It may cause jaundice.
Investigational
Withdrawn
Matched Synonyms: … 3,3-Bis(p-hydroxyphenyl)-2-indolinone ... 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-2H-indol-2-one …
Matched Iupac: … 3,3-bis(4-hydroxyphenyl)-2,3-dihydro-1H-indol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3,3-bis(4-hydroxyphenyl)-2,3-dihydro-1H-indol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Isatoic anhydride
Experimental
BMN-351
BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA. It is under investigation for the treatment of Duchenne Muscular Dystrophy (DMD).
Investigational
Matched Description: … BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to …
Veverimer
Veverimer is under investigation in clinical trial NCT03390842 (Long-term Safety Extension to Study TRCA-301).
Investigational
Matched Synonyms: … 1,3-propanediamine, n1,n3-di-2-propen-1-yl-, polymer with 1,2-dichloroethane and 2-propen-1-amine ... N1,n3-bis(prop-2-en-1-yl)propan-1,3-diamine copolymer with 1,2-dichloroethane and prop-2-en-1-amine …
2,5-Dimethylpyrimidin-4-Amine
Experimental
L-tartaric acid
Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Experimental
Matched Mixtures name: … E-Z-gas 2 Granules …
Danavorexton
Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)-, methyl ... Methyl (2r,3s)-3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate ... Methyl (2R,3S)-3-[(Methylsulfonyl)Amino]-2-{[(Cis-4-Phenylcyclohexyl)Oxy]Methyl}Piperidine-1-Carboxylate …
Matched Iupac: … methyl (2R,3S)-3-methanesulfonamido-2-({[(1s,4s)-4-phenylcyclohexyl]oxy}methyl)piperidine-1-carboxylate …
Matched Iupac: … methyl (2R,3S)-3-methanesulfonamido-2-({[(1s,4s)-4-phenylcyclohexyl]oxy}methyl)piperidine-1-carboxylate …
Gildeuretinol
Investigational
3,5-Difluorobenzenesulfonamide
Experimental
Beta-D-Glucopyranose Spirohydantoin
Experimental
4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID
Experimental
Matched Name: … 4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID …
Matched Iupac: … (3Z)-4-(2-methoxyphenyl)-2-oxobut-3-enoic acid …
Matched Iupac: … (3Z)-4-(2-methoxyphenyl)-2-oxobut-3-enoic acid …
L-threonic acid
Experimental
Nicotinamide Mononucleotide
3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]
Experimental
Matched Iupac: … 3-carbamoyl-1-[(2R,3R,4R,5S)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-1lambda5-pyridin-1-ylium …
Matched Description: … 3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. …
Matched Description: … 3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. …
(S)-Warfarin
Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Investigational
Matched Synonyms: … (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone ... 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Description: … S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] …
Matched Iupac: … 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Description: … S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] …
AZD-5153
Investigational
Matched Synonyms: … 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin ... -2-one …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin ... -2-one …
meso-Tartaric acid
Experimental
[(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron
Experimental
Matched Name: … [(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-2-(4-chlorophenyl)-1-acetamidoethyl]dihydroxyboranuide …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-2-(4-chlorophenyl)-1-acetamidoethyl]dihydroxyboranuide …
Eprenetapopt
Eprenetapopt has been used in trials studying the treatment of Prostatic Neoplasms, Hematologic Neoplasms, and Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53.
Investigational
Matched Synonyms: … 3-QUINUCLIDINONE, 2-(HYDROXYMETHYL)-2-(METHOXYMETHYL)- ... 1-Azabicyclo(2.2.2)octan-3-one, 2-(hydroxymethyl)-2-(methoxymethyl)- ... 2-hydroxymethyl-2-methoxymethyl-1-azabicyclo[2,2,2]octan-3-one …
Matched Iupac: … 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one …
Matched Iupac: … 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one …
Displaying drugs 5801 - 5825 of 10413 in total