L-threonic acid
Star2
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Brand Names
- EnBrace HR, EnLyte
- Generic Name
- L-threonic acid
- DrugBank Accession Number
- DB11192
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 136.1033
Monoisotopic: 136.037173366 - Chemical Formula
- C4H8O5
- Synonyms
- (2R,3S)-2,3,4-trihydroxy-butanoic acid
- L-threonate
- L-threonic acid
- Threonate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Magnesium L-threonate 1Y26ZZ0OTM 778571-57-6 YVJOHOWNFPQSPP-BALCVSAKSA-L - Active Moieties
Name Kind UNII CAS InChI Key Threonic acid unknown NTD0MI8XRT 3909-12-4 JPIJQSOTBSSVTP-GBXIJSLDSA-N - Unapproved/Other Products
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group.
- Kingdom
- Organic compounds
- Super Class
- Organic oxygen compounds
- Class
- Organooxygen compounds
- Sub Class
- Carbohydrates and carbohydrate conjugates
- Direct Parent
- Sugar acids and derivatives
- Alternative Parents
- Short-chain hydroxy acids and derivatives / Beta hydroxy acids and derivatives / Monosaccharides / Fatty acids and conjugates / Alpha hydroxy acids and derivatives / Secondary alcohols / Polyols / Monocarboxylic acids and derivatives / Carboxylic acids / Primary alcohols show 3 more
- Substituents
- Alcohol / Aliphatic acyclic compound / Alpha-hydroxy acid / Beta-hydroxy acid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative / Fatty acid / Hydrocarbon derivative / Hydroxy acid show 8 more
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- threonic acid (CHEBI:15908)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 75B0PMW2JF
- CAS number
- 7306-96-9
- InChI Key
- JPIJQSOTBSSVTP-STHAYSLISA-N
- InChI
- InChI=1S/C4H8O5/c5-1-2(6)3(7)4(8)9/h2-3,5-7H,1H2,(H,8,9)/t2-,3+/m0/s1
- IUPAC Name
- (2R,3S)-2,3,4-trihydroxybutanoic acid
- SMILES
- [H][C@](O)(CO)[C@@]([H])(O)C(O)=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0062620
- ChemSpider
- 4573940
- BindingDB
- 50392477
- 1547558
- ChEBI
- 15908
- ChEMBL
- CHEMBL2152047
- ZINC
- ZINC000000901061
- PDBe Ligand
- LTH
- Wikipedia
- Threonic_acid
- PDB Entries
- 4pe6
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data4 Withdrawn Treatment Menstrual Related Mood Disorder / Premenstrual Dysphoric Disorder (PMDD) / Premenstrual Syndrome (PMS) / Premenstrual tension with edema 1 somestatus stop reason just information to hide 2 Completed Treatment Attention Deficit Hyperactivity Disorder (ADHD) 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule, liquid filled Oral Capsule, delayed release pellets Oral Capsule Oral Tablet, chewable Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 488.0 mg/mL ALOGPS logP -2.1 ALOGPS logP -2.1 Chemaxon logS 0.55 ALOGPS pKa (Strongest Acidic) 3.4 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 97.99 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 26.35 m3·mol-1 Chemaxon Polarizability 11.61 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 122.7421756 predictedDarkChem Lite v0.1.0 [M-H]- 123.7691756 predictedDarkChem Lite v0.1.0 [M-H]- 122.8303756 predictedDarkChem Lite v0.1.0 [M-H]- 124.7687756 predictedDarkChem Lite v0.1.0 [M-H]- 122.25959 predictedDeepCCS 1.0 (2019) [M+H]+ 123.5465756 predictedDarkChem Lite v0.1.0 [M+H]+ 124.2725756 predictedDarkChem Lite v0.1.0 [M+H]+ 123.5619756 predictedDarkChem Lite v0.1.0 [M+H]+ 126.9797756 predictedDarkChem Lite v0.1.0 [M+H]+ 126.1245 predictedDeepCCS 1.0 (2019) [M+Na]+ 122.1962756 predictedDarkChem Lite v0.1.0 [M+Na]+ 123.2097756 predictedDarkChem Lite v0.1.0 [M+Na]+ 122.3049756 predictedDarkChem Lite v0.1.0 [M+Na]+ 125.0860756 predictedDarkChem Lite v0.1.0 [M+Na]+ 135.17473 predictedDeepCCS 1.0 (2019)
Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53