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Displaying drugs 5851 - 5875 of 10346 in total

Cinnamic acid

Investigational
Matched Synonyms: … 2-propenoic acid, 3-phenyl- ... 3-phenyl-2-propenoic acid ... 2-propenoic acid, 3-phenyl-, (2e)- …
Matched Iupac: … (2E)-3-phenylprop-2-enoic acid …

(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol

(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. This compound belongs to the benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. This substance is known to target disintegrin and metalloproteinase domain-containing protein 17.
Experimental
Matched Name: … (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol …
Matched Iupac: … (3S)-1-[4-(but-2-yn-1-yloxy)benzenesulfonyl]pyrrolidine-3-thiol …
Matched Description: … (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. …

Methylpropylpropanediol dinitrate

Experimental
Matched Synonyms: … 2-methyl-2-propylpropane-1,3-diyl dinitrate …
Matched Iupac: … 2-methyl-1-(nitrooxy)-2-[(nitrooxy)methyl]pentane …

Dimethyltryptamine

An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Experimental
Illicit
Matched Synonyms: … 2-(3-indolyl)ethyldimethylamine ... 3-(2-dimethylaminoethyl)indole ... 3-[2-(dimethylamino)ethyl]indole …
Matched Iupac: … [2-(1H-indol-3-yl)ethyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

(2E)-3-(4-CHLOROPHENYL)-N-HYDROXYACRYLAMIDE

Experimental
Matched Name: … (2E)-3-(4-CHLOROPHENYL)-N-HYDROXYACRYLAMIDE …
Matched Iupac: … (2E)-3-(4-chlorophenyl)-N-hydroxyprop-2-enamide …

Venadaparib

Investigational
Matched Synonyms: … 1(2h)-phthalazinone, 4-((3-((3-((cyclopropylamino)methyl)-1-azetidinyl)carbonyl)-4-fluorophenyl)methyl ... 4-((3-((3-((cyclopropylamino)methyl)-1-azetidinyl)carbonyl)-4-fluorophenyl)methyl)-1(2h)-phthalazinone …
Matched Iupac: … 4-[(3-{3-[(cyclopropylamino)methyl]azetidine-1-carbonyl}-4-fluorophenyl)methyl]-1,2-dihydrophthalazin …

(2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide

Experimental
Matched Name: … (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide …
Matched Iupac: … (2R)-N-hydroxy-3-(naphthalen-2-yl)-2-(naphthalene-2-sulfonamido)propanamide …

3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide

Experimental
Matched Name: … 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide …
Matched Iupac: … 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(4-sulfamoylphenyl)-1-benzofuran-6-sulfonamide …

Nezastomig

Nezastomig is under investigation in clinical trial NCT06085664 (A Pilot Presurgical Trial of REGN5678 (Anti-psma X CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy).
Investigational

N-{3-[(7ar,12as,12bs)-7-Oxo-1,3,4,6,7,7a,12a,12b-Octahydroindolo[2,3-a]Quinolizin-12(2h)-Yl]Propyl}Propane-2-Sulfonamide

Experimental
Matched Name: … -2-Sulfonamide ... N-{3-[(7ar,12as,12bs)-7-Oxo-1,3,4,6,7,7a,12a,12b-Octahydroindolo[2,3-a]Quinolizin-12(2h)-Yl]Propyl}Propane …
Matched Iupac: … N-{3-[(12bS)-7-oxo-1H,2H,3H,4H,6H,7H,12H,12bH-indolo[2,3-a]quinolizin-12-yl]propyl}propane-2-sulfonamide …

1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide

Experimental
Matched Name: … 1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen …
Matched Iupac: … -1-yl]pyrrolidine-2-carboxamide ... (2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)propanamido]butanoyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen …

{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid

Experimental
Matched Name: … {4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2- …
Matched Iupac: … 2-{4-[(2S)-2-{[(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl]carbamoyl}-2-acetamidoethyl]-2-phosphonophenoxy …

2-amino-3-(4-amino-1H-indol-3-yl)propanoic acid

Experimental
Matched Name: … 2-amino-3-(4-amino-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-amino-1H-indol-3-yl)propanoic acid …

PF-06842874

Investigational
Matched Synonyms: … 3-acetyl-1-cyclopentyl-7-(((3s,4r)-3-hydroxyoxan-4-yl)amino)-4-methyl-1,6-naphthyridin-2(1h)-one ... 3-Acetyl-1-cyclopentyl-7-{[(3S,4R)-3-hydroxyoxan-4-yl]amino }-4-methyl-1,6-naphthyridin-2(1H)-one …
Matched Iupac: … 3-acetyl-1-cyclopentyl-7-{[(3S,4R)-3-hydroxyoxan-4-yl]amino}-4-methyl-1,2-dihydro-1,6-naphthyridin-2- …

Tirapazamine

Tirapazamine, also known as SR-4233, is an experimental anticancer drug that is activated in hypoxic conditions. This activation is very useful as this hypoxic state is found in human solid tumors in a common phenomenon known as tumor hypoxia. Hence, tirapazamine is solely activated in those hypoxic areas of solid...
Investigational
Matched Synonyms: … 1,2,4-benzotriazin-3-amine, 1,4-dioxide ... 3-Amino-1,2,4-benzotriazine 1,4-dioxide …
Matched Iupac: … 3-amino-1,2,4-benzotriazine-1,4-diium-1,4-bis(olate) …

beta-2-Thienyl-L-alanine

Experimental
Matched Synonyms: … L-3-(2-thienyl)alanine ... beta-(2-Thienyl)-L-alanine …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …

Alvocidib

Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Experimental
Investigational
Matched Iupac: … 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one …
Matched Salts cas: … 131740-09-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

2,3-Difluorobenzyl Alcohol

Experimental

S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate

Experimental
Matched Name: … S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate …
Matched Iupac: … [(3S)-3-[(2-{[2-(hexanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy]phosphonic …

S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate

Experimental
Matched Name: … S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate …
Matched Iupac: … [(3S)-3-hydroxy-2,2-dimethyl-3-[(2-{[2-(octanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphonic …

3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one

Experimental
Matched Name: … 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one …
Matched Iupac: … 3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-3-yl]-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …

Olafertinib

Investigational
Matched Synonyms: … N-(3-(2-(2,3-difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenylamino)quinazolin-8-yl)phenyl)acrylamide …

1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide

Experimental
Matched Name: … 1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …

2-Amino-4-(4-Amino-Cyclohexa-2,5-Dienyl)-Butyric Acid

Experimental
Matched Name: … 2-Amino-4-(4-Amino-Cyclohexa-2,5-Dienyl)-Butyric Acid …
Matched Iupac: … (2S)-2-amino-4-(4-aminocyclohexa-2,5-dien-1-yl)butanoic acid …

Tenalisib

Tenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).
Investigational
Matched Synonyms: … (S)-2-(1-(9H-Purin-6-Ylamino)Propyl)-3-(3-Fluorophenyl)-4H-Chromen-4-One) ... 3-(3-FLUOROPHENYL)-2-((1S)-1-((7H-PURIN-6-YL)AMINO)PROPYL)-4H-1-BENZOPYRAN-4-ONE ... 4H-1-BENZOPYRAN-4-ONE, 3-(3-FLUOROPHENYL)-2-((1S)-1-(9H-PURIN-6-YLAMINO)PROPYL)- …
Matched Iupac: … 3-(3-fluorophenyl)-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphoinositide-3 Kinase Inhibitors …
Displaying drugs 5851 - 5875 of 10346 in total