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Displaying drugs 576 - 600 of 1840 in total
An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
Experimental
Illicit
Matched Synonyms: … (+)-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine ... D-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine ... 4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine …
Matched Iupac: … (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one …
Matched Description: … An opioid analgesic structurally related to methadone and used in the treatment of severe pain. …
Gandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Investigational
Matched Synonyms: … IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, 3-((4-CHLORO-2-FLUOROPHENYL)METHYL)-2-METHYL-N-(5- METHYL-1H-PYRAZOL ... 3-(4-CHLORO-2-FLUOROBENZYL)-2-METHYL-N-(5-METHYL-1H-PYRAZOL-3-YL)-8- (MORPHOLINOMETHYL)IMIDAZO(1,2-B) …
Matched Iupac: … N-{3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-8-[(morpholin-4-yl)methyl]imidazo[1,2-b]pyridazin-6-yl ... }-5-methyl-1H-pyrazol-3-amine …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and
Hydronidone has antifibrotic activity.
Investigational
Matched Synonyms: … N-(4-Hydroxyphenyl)-5-methyl-2-pyridone …
Matched Iupac: … 1-(4-hydroxyphenyl)-5-methyl-1,2-dihydropyridin-2-one …
Experimental
Matched Synonyms: … Deamino-methyl-phenylalanine …
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Experimental
Matched Synonyms: … 2-methyl-2-propylpropane-1,3-diyl dinitrate …
Matched Iupac: … 2-methyl-1-(nitrooxy)-2-[(nitrooxy)methyl]pentane …
Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions . Due to its antimicrobial properties following topical administration, minimal levels of iodoform may be found in disinfectants and it is more...
Approved
Experimental
Vet approved
Matched Synonyms: … methyl triiodide …
Matched Description: … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. ... dressing or powder for wounds and sores, however such clinical use to this date is limited. ... properties following topical administration, minimal levels of iodoform may be found in disinfectants and
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … -3-yl)methyl)-1-methyl-, inner salt ... (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane ... 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl ... }-3-methyl-1H-1,2,3-triazol-3-ium …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … Benzamides and benzamide derivatives …
Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and Winner. It is marketed as pest...
Vet approved
Matched Synonyms: … 1-((6-chloro-3-Pyridyl)methyl)-N-nitro-2-imidazolidinimine ... 1-((6-chloro-3-Pyridinyl)methyl)-N-nitro-2-imidazolidinimine ... (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine …
Matched Iupac: … 2-chloro-5-{[2-(nitroamino)-4,5-dihydro-1H-imidazol-1-yl]methyl}pyridine …
Matched Description: … under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and ... Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and ... It is marketed as pest control, seed treatment, an insecticide spray, termite control, flea control, and
Matched Mixtures name: … Advocate Spot-on Solution for Small Cats and Ferrets …
Experimental
Matched Name: … 5-(Hydroxy-Methyl-Amino)-3-Methyl-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5R)-5-[hydroxy(methyl)amino]-3-methylpyrrolidine-2-carboxylic acid …
Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.
Investigational
Matched Synonyms: … 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amine …
Matched Iupac: … 1-[({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl}oxy)methyl]cyclopropan-1-amine …
Matched Description: … Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal …
Investigational
Matched Synonyms: … N-hydroxy-4-((4-((((1R,2S)-2-phenylcyclopropyl) amino)methyl)-1H-pyrazol-1-yl)methyl)benzamide hydrogen …
Investigational
Matched Synonyms: … 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)benzoic acid ... Benzoic acid, 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)- …
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin ... 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine …
Matched Iupac: … 4-methyl-N-[2-(morpholin-4-yl)ethyl]-6-phenylpyridazin-3-amine …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and
Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of...
Experimental
Illicit
Matched Synonyms: … 3alpha-Ethyl-1-methyl-4-phenyl-4alpha-piperidyl propionat ... alpha-3-ethyl-1-methyl-4-phenyl-4-propionoxypiperidine ... alpha-3-Ethyl-1-methyl-4-phenyl-4-propionyloxypiperidine …
Matched Iupac: … (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … as well as itching, nausea, and respiratory depression. ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Approved
Illicit
Matched Synonyms: … 2α-Methyl-4,5-dihydrotestosterone propionate ... 17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate ... Testosterone, 4,5α-dihydro-2α-methyl-, propionate …
Matched Categories: … Testosterone and derivatives …
Investigational
Matched Synonyms: … 1-pyrrolidinecarboximidamide, n-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)- ... 1-Pyrrolidinecarboximidamide, N-[imino[[4-(trifluoromethoxy)phenyl]amino]methyl]- ... N-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)-1-pyrrolidinecarboximidamide …
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Synonyms: … alpha-Methyl-1-adamantanemethylamine …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
TIMBD is an azaresveratrol analog.
Experimental
Matched Synonyms: … 2-Methoxy-6-[[(4-methylphenyl)imino]methyl]phenol …
Matched Name: … 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol …
Matched Iupac: … 2-methoxy-6-[(1E)-[(4-methylphenyl)imino]methyl]phenol …
Investigational
Matched Synonyms: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]-indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Experimental
Investigational
Matched Synonyms: … 5-methyl-1,2,4-triazolo(3,4-b)benzothiazole ... 5-methyl-1,2,4-triazolo(3,4-b)(1,3)benzothiazole …
Matched Iupac: … 12-methyl-7-thia-2,4,5-triazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),3,5,8,10-pentaene …
WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of...
Experimental
Matched Synonyms: … (2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl …
Matched Iupac: … (11R)-2-methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12 …
Matched Description: … It activates p42 and p44 MAP kinase via receptor-mediated signaling. …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Investigational
Matched Synonyms: … 1h-benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfonyl)- …
Matched Iupac: … 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfonyl}-1H-1,3-benzodiazole …
Investigational
Matched Synonyms: … Methyl 4-{[2-(acetamino)ethyl]sulfanyl}-4-oxobutanoate ... Butanoic acid, 4-[[2-(acetylamino)ethyl]thio]-4-oxo-, methyl ester …
Matched Iupac: … methyl 4-[(2-acetamidoethyl)sulfanyl]-4-oxobutanoate …
Displaying drugs 576 - 600 of 1840 in total