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Displaying drugs 6101 - 6125 of 11078 in total

AR-42

AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and Vestibular Schwannoma, among others.
Investigational
Matched Synonyms: … (S)-(+)-N-HYDROXY-4-(3-METHYL-2-PHENYL-BUTYRYLAMINO)-BENZAMIDE ... N-Hydroxy-4-(3-methyl-2-(S)phenyl-butyrylamino)benzamide ... N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide …
Matched Iupac: … N-hydroxy-4-[(2S)-3-methyl-2-phenylbutanamido]benzamide …

Caprospinol

Caprospinol (SP-233) is the first drug ever to demonstrate the correlation of clearing beta-amyloid from the brain. It also improves the brain histopathology and recovers memory function.
Investigational
Matched Iupac: … (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,16'S)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …

Surinabant

Surinabant has been investigated for the treatment of Smoking Cessation.
Investigational
Matched Iupac: … 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

7,10,13-Tri(Carboxymethyl)-5,15-Dioxo-4,7,10,13,16-Pentaaza-1,19-Dithianonadecane

Experimental
Matched Iupac: … 2-[bis({2-[(carboxymethyl)({[(2-sulfanylethyl)carbamoyl]methyl})amino]ethyl})amino]acetic acid …

GBR-12783

A selective inhibitor of dopamine uptake.
Investigational
Matched Iupac: … 1-[2-(diphenylmethoxy)ethyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-chloroethyl-3-sarcosinamide-1-nitrosourea

2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Synonyms: … 2-chloroethyl-3-sarcosinamide-1-nitrosourea ... ACETAMIDE, 2-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)METHYLAMINO)- …
Matched Name: … 2-chloroethyl-3-sarcosinamide-1-nitrosourea …
Matched Iupac: … 2-{[N-(2-chloroethyl)-N'-oxohydrazinecarbonyl](methyl)amino}acetamide …
Matched Description: … 2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal …

3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid

Experimental
Matched Name: … 3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid …
Matched Iupac: … 3-{[(Z)-[(2-methoxyphenyl)methylidene]amino]oxy}propanoic acid …

3'-beta-Sialyl-beta-lactose

Experimental
Matched Synonyms: … O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose …
Matched Name: … 3'-beta-Sialyl-beta-lactose …
Matched Iupac: … -2-(hydroxymethyl)oxan-3-yl]oxy}oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl ... ]oxane-2-carboxylic acid ... (2S,4S,5R,6R)-2-{[(2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy …

Ipafricept

Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors).
Investigational

2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide

Experimental
Matched Name: … 2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluorobenzamide …

2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid

Experimental
Matched Name: … 2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid …
Matched Iupac: … 2-{[3,5-dichloro-4-(hydroxyperoxy)phenyl]amino}benzoic acid …

KB-141

An anticholesteremic agent.
Experimental
Matched Synonyms: … 3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)phenylacetic acid …
Matched Iupac: … 2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl}acetic acid …

Cilansetron

Cilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase in the EU and US.
Investigational
Matched Iupac: … (12R)-12-[(2-methyl-1H-imidazol-1-yl)methyl]-1-azatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5(16), …
Matched Description: … Cilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

3,6,9,12,15-Pentaoxaheptadecane

Experimental

1-(c14-c18 esteroyl)-2-docosahexanoyl-sn-glycero-3-phosphoethanolamine

Experimental
Matched Name: … 1-(c14-c18 esteroyl)-2-docosahexanoyl-sn-glycero-3-phosphoethanolamine …

6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE

Experimental
Matched Name: … 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)pyridin-2-amine …

(3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE

Experimental
Matched Name: … (3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE …
Matched Iupac: … ({4-[(3aS,4R,8aS,8bR)-2-[(4-fluorophenyl)methyl]-1,3-dioxo-decahydropyrrolo[3,4-a]pyrrolizin-4-yl]phenyl …

Cordycepin Triphosphate

Experimental
Matched Iupac: … ({[({[(2S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Rivanicline

Rivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. It has subsequently been developed...
Investigational
Matched Synonyms: … (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine ... (E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine ... N-methyl-4-(3-pyridinyl)-(3E)-3-buten-1-amine …
Matched Iupac: … methyl[(3E)-4-(pyridin-3-yl)but-3-en-1-yl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bersanlimab

Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Anti-icam-1 monoclonal antibody bi-505 ... Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), ... .1-chain), disulfide with monoclonal bi-505 light-chain, dimer …
Matched Description: … (ICAM-1). ... Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 …

Retlirafusp alfa

Investigational
Matched Synonyms: … phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human programmed death-ligand 1) ... ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor (human isoform 1) …

(2R)-2-ETHYL-1-HEXANESULFONIC ACID

Experimental
Matched Name: … (2R)-2-ETHYL-1-HEXANESULFONIC ACID …
Matched Iupac: … {[(2R)-2-ethylhexyl]oxy}sulfonic acid …

N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE

Experimental
Matched Name: … N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE …
Matched Iupac: … benzyl N-[(1S)-1-{[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamoyl}-3-methylbutyl]carbamate …

Piclozotan

Piclozotan has been investigated for the treatment of Parkinson's Disease.
Investigational
Matched Iupac: … 3-chloro-4-(4-{1',2',3',6'-tetrahydro-[2,4'-bipyridine]-1'-yl}butyl)-4,5-dihydro-1,4-benzoxazepin-5-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists …

1,1'-BIPHENYL-2-SULFINIC ACID

Experimental
Matched Name: … 1,1'-BIPHENYL-2-SULFINIC ACID …
Matched Iupac: … (R)-[1,1'-biphenyl]-2-sulfinic acid …
Displaying drugs 6101 - 6125 of 11078 in total